Results 121 to 130 of about 88,849 (292)

Enhanced stability of sulfamethoxazole and trimethoprim against oxidation using hydroxypropyl-B-cyclodextrin

, 2005
The effect of hydroxypropyl-β-cyclodextrin (HPβCD) on the chemical stability of sulfamethoxazole and trimethoprim (co-trimoxazole) under oxidation stress at 50 ± 2 °C was investigated.
Glenn Jacobson (14740078), Pourmokhtar, M (15504083)   +1 more
core  

Recent advances in chiral organic room‐temperature phosphorescence with circularly polarized luminescence

FlexMat, EarlyView.
This review systematically summarizes representative recent advances in organic circularly polarized room‐temperature phosphorescence materials toward optoelectronic and information security applications. Abstract Circularly polarized room‐temperature phosphorescence (CPRTP) materials combine the dual advantages of long‐lived triplet emission and ...
Liang Zhang, Ming‐Jun Ji, Chuan‐Feng Chen   +2 more
wiley   +1 more source

Thermophoresis of cyclodextrins and cyclodextrin-drug-complexes

, 2017
The behaviour of biomolecules in a temperature gradient, known as thermodiffusion, changes when a ligand binds. In recent years, this effect has been used to gain detailed information on binding dynamics, although the physicochemical processes are still unclear [1].
Niether, Doreen, Kawaguchi, Tsubasa, Hovancova, Jana, Eguchi, Kazuja, Dhont, Jan K.G., Kita, Rio, Wiegand, Simone   +6 more
openaire   +1 more source

Structural Properties and Hydrogen-Bond Dynamics of Water Confined in Cyclodextrin-Based Hydrogel

, 2013
Cyclodextrin nanosponges (CDNS) are a very promising class of cross-linked polymers, made up of cyclodextrins, which can swell in aqueous solution giving rise to an interesting gel-like behavior. These cyclodextrin-based materials show notable properties
B Rossi, F Castiglione, L Melone, A Mele, C Punta, F TrottaV Crupi, D Majolino, V Venuti, W Liang, Y Inoue, A Fontana, W Panzeri, F Rossi, C Yang   +13 more
core  

Chemistry Underlying the Behavior of Food and Agricultural Components During Industrial Manufacturing Processes and Its Implications in Quality Assurance, Food Quality, and Food Safety Management: A Systematic Review

Food Safety and Health, EarlyView.
Industrial manufacturing processes have transformative effects on the components of food matrix. These transformations in food matrix and components have direct implications for quality assurance (QA), food quality (e.g., nutritional profile and texture), and food safety management (e.g., pathogen control and toxin mitigation). ABSTRACT This systematic
Chinaza Godswill Awuchi
wiley   +1 more source

Hepatocyte‐Centered Regulation of MASH Fibrosis: From Animal Models to Molecular Mechanisms and Targeted Therapies

iNew Medicine, EarlyView.
This review highlights hepatocytes as active regulators of MASH fibrosis through secreted proteins, metabolites, and extracellular vesicles that modulate hepatic stellate cell activation. These hepatocyte–stellate cell communication pathways provide a mechanistic framework for developing targeted antifibrotic therapies, including hepatocyte‐directed ...
Eui Jung Jung, Xiaobo Wang
wiley   +1 more source

Specific peptide enrichment strategies for neuropsychiatric disorders: From material design to diagnostic applications

Interdisciplinary Medicine, EarlyView.
This review outlines specific peptide enrichment strategies, including metal, magnetic oxides, functional polymers, and antibody‐based approaches, and their mechanisms, highlighting applications in biomarker discovery for major neurological and psychiatric disorders.
Xue Zhang, Yejiao Shi, Minghui Guo, Yang Huang, Yirong Wang, Leping Huang, Helena S. Azevedo, Honggang Hu, Xin Dong   +8 more
wiley   +1 more source

Chlorfenapyr Induces Hepatotoxicity Associated With Oxidative Stress and Mitochondrial Dysfunction Involving Keap1/Nrf2 Signaling

Journal of Applied Toxicology, EarlyView.
ABSTRACT Chlorfenapyr (CHL) is a widely used pyrrole insecticide, but its hepatotoxic effects and underlying mechanisms remain incompletely understood. This study investigated the toxic effects of CHL on rat liver and BRL‐3A hepatocytes and explored the involvement of the Keap1/Nrf2 signaling pathway. Rats were administered CHL (10, 20, or 30 mg/kg) by
Dongquan Zhao, Jia Li, Cheng Li, Hua He, Lipu Deng   +4 more
wiley   +1 more source

Illuminating Streptomyces: Raman Spectroscopy for Antibiotic Detection and Monitoring

Journal of Raman Spectroscopy, EarlyView.
Raman spectroscopy provides a non‐destructive, label‐free approach for studying the chemical diversity of Streptomyces. This review presents its application from detection to chemical characterization of secondary metabolites and monitoring of biosynthetic processes.
Adéla Mikulová, Jan Bobek, Martin Kizovský, Markéta Benešová, Ota Samek, Pavlína Modlitbová, Zdeněk Pilát   +6 more
wiley   +1 more source

From nature to nanoscale: advances, challenges, and preclinical translation of nanofiber drug delivery systems containing plant‐derived active ingredients

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Since the early 1960s, nanotechnology has been a critical area of science, allowing for the development of sophisticated nanomaterials. Nanofibers, one of the most widely used nanotechnological drug delivery systems, have emerged as a highly versatile platform within modern pharmaceutical sciences.
Heybet Kerem Polat, Yasin Turanlı, Nihat Kurt, Sefa Gözcü, Emre Tunçel, Hilal Bacanak, Eren Aytekin, Sedat Ünal   +7 more
wiley   +1 more source