Results 271 to 280 of about 236,794 (382)

The Contribution of Cholesterol and Squalene Synthase in Cancer: Molecular Mechanisms, Lipid Rafts and Therapeutic Approaches

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT A plethora of cellular signaling pathways are dysregulated in cancer cells, promoting carcinogenesis and migration. Cholesterol has recently been linked to cancer by several subcellular mechanisms, especially by its involvement in the formation of lipid rafts, which promote oncogenic signaling and cancer cell invasion. Squalene synthase (SQS),
Danai Mavridi   +2 more
wiley   +1 more source

Validation of a UV spectrophotometric method for determining trans-dehydrocrotonin in inclusion complexes with hydroxypropyl-β-cyclodextrin [PDF]

open access: green, 2012
Nereide Stela Santos-Magalhães   +4 more
openalex  

Plasmodesmata‐located proteins: The molecular hubs in noncell‐autonomous immunity

open access: yesNew Plant Protection, EarlyView.
Plasmodesmata serve as critical battlefields for plant immunity, regulated by diverse proteins. This article provides a comprehensive review of the regulatory mechanisms, challenges, and future directions concerning proteins located within plasmodesmata and their roles in plant defense responses.
Zheng Wu, Xiaoyi Shan
wiley   +1 more source

Structural Basis of the Light‐Switchable Interaction between an Azobenzene Side Chain in a Biosynthetic Protein and α‐Cyclodextrin

open access: yesChemistryOpen, EarlyView.
X‐ray crystallographic analysis of super‐folder green fluorescent protein (sfGFP), a common reporter protein, displaying p‐(phenylazo)‐L‐phenylalanine (Pap) at amino acid position 39 on its surface in complex with α‐cyclodextrin (α‐CD) reveals an unexpected conformation of the photoswitchable side chain and illustrates its light‐dependent ...
Andreas Eichinger   +4 more
wiley   +1 more source

Diverse reactivity of maleimides in polymer science and beyond

open access: yesPolymer International, Volume 74, Issue 4, Page 296-306, April 2025.
This mini‐review provides a thorough overview of maleimide chemistry, highlighting its diverse reactivity in polymer and materials science applications. Abstract Maleimides are remarkably versatile functional groups, capable of participating in homo‐ and copolymerizations, Diels–Alder and (photo)cycloadditions, Michael additions, and other reactions ...
Bruce E Kirkpatrick   +2 more
wiley   +1 more source

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