Results 121 to 130 of about 12,599 (260)

Chlorfenapyr Induces Hepatotoxicity Associated With Oxidative Stress and Mitochondrial Dysfunction Involving Keap1/Nrf2 Signaling

Journal of Applied Toxicology, EarlyView.
ABSTRACT Chlorfenapyr (CHL) is a widely used pyrrole insecticide, but its hepatotoxic effects and underlying mechanisms remain incompletely understood. This study investigated the toxic effects of CHL on rat liver and BRL‐3A hepatocytes and explored the involvement of the Keap1/Nrf2 signaling pathway. Rats were administered CHL (10, 20, or 30 mg/kg) by
Dongquan Zhao, Jia Li, Cheng Li, Hua He, Lipu Deng   +4 more
wiley   +1 more source

Cyclodextrins as Modulators of Regulated Cell Death: Implications for Immunometabolism and Therapeutic Innovation. [PDF]

Pharmaceutics
Trasca DM, Mocanu AG, Pluta ID, Popescu C, Stoica GA, Varut RM, Preoteasa D, Vintilescu ȘB, Stepan MD, Singer CE, Pirscoveanu DFV.   +10 more
europepmc   +1 more source

Hybrid Quatsome‐Encapsulated Silver Nanoparticles as Stable Plasmonic Substrates for Surface‐Enhanced Raman Scattering

Journal of Raman Spectroscopy, EarlyView.
In this work, silver nanoparticles encapsulated within quatsome membranes have shown to preserve their plasmonic properties for at least 165 days without aggregation. These hybrid nanostructures enable strong SERS enhancement of pyrene and Prodan by confining the molecules within a few nanometers from the silver surface.
Renato Cezar Peramezza Ribeiro, Caio Hiroaki Miyake, Pedro Henrique Figueiredo Backes Costa, Jhenifer Hallen Braga Mauricio, Ana Luiza Correa Januário, Diogo Soga, Evandro Luiz Duarte, Márcia de Almeida Rizzutto, Rômulo Augusto Ando, Antonio Rodrigues da Cunha, Erix Alexander Milán‐Garcés   +10 more
wiley   +1 more source

Cyclodextrins improve grape must fermentability through their detoxifying effect on medium-chain fatty acids. [PDF]

Food Chem X
Galán NG, Sabaté AC, Borràs AJ, Yoldi DG, Rozès N, Fort F, Canals JM, Zamora F, Gombau J.   +8 more
europepmc   +1 more source

Controllable DNA Condensation by Mixed Cationic Gemini/Nonionic Surfactant Systems: Structure, Thermodynamics, and Cytotoxicity

Journal of Surfactants and Detergents, EarlyView.
ABSTRACT Controllable DNA condensation is important for nucleic‐acid packaging and non‐viral gene‐delivery systems. This study aimed to determine how the composition of mixed nonionic C12E10 and cationic gemini C12C6C12Br2 surfactants regulates DNA condensation, structure, thermodynamics, and cytotoxicity.
Bo Wang, Linyi Zhu, Yaxun Fan, Yilin Wang   +3 more
wiley   +1 more source

Cyclodextrin-Based Strategies for Brain Drug Delivery: Mechanistic Insights into Blood-Brain Barrier Transport and Therapeutic Applications. [PDF]

Pharmaceutics
Vasilica PDF, Dorin PI, Vladulescu C, Popescu C, Trasca DM, Radivojevic K, Varut RM, Vintilescu ȘB, Stepan MD, Stoica GA.   +9 more
europepmc   +1 more source

From nature to nanoscale: advances, challenges, and preclinical translation of nanofiber drug delivery systems containing plant‐derived active ingredients

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Since the early 1960s, nanotechnology has been a critical area of science, allowing for the development of sophisticated nanomaterials. Nanofibers, one of the most widely used nanotechnological drug delivery systems, have emerged as a highly versatile platform within modern pharmaceutical sciences.
Heybet Kerem Polat, Yasin Turanlı, Nihat Kurt, Sefa Gözcü, Emre Tunçel, Hilal Bacanak, Eren Aytekin, Sedat Ünal   +7 more
wiley   +1 more source

Organic supramolecular assemblage-confined photoluminescence. [PDF]

Chem Sci
Zhang H, Liu Y.
europepmc   +1 more source

Crystallization in Poly(Ethylene Oxide) Thin Films: Roles of Shear, Confinement, and Homoepitaxy

Macromolecular Rapid Communications, EarlyView.
A comprehensive three‐mechanism framework governing PEO crystallization orientation in thin films was established using GIWAXS and molecular‐level PM‐IRRAS analysis. We demonstrate systematic switching between shear‐induced edge‐on and confinement‐ or homoepitaxy‐induced flat‐on alignment.
Cong Liu, Sinan Feng, Shuntaro Uenuma, Atsushi Takahara, Kohzo Ito   +4 more
wiley   +1 more source

Computational Investigation of 4‑Nitrophenol Inclusion Complexes with α‑, β‑, and γ‑Cyclodextrins. [PDF]

ACS Omega
Vendrame LFO, Tonel MZ, da Rocha JAP, Zanella I, Rhoden CRB, Fagan SB.   +5 more
europepmc   +1 more source