Results 21 to 30 of about 26,778 (245)

β-Cyclodextrins as affordable antivirals to treat coronavirus infection [PDF]

open access: yes, 2023
The SARS-CoV-2 pandemic made evident that there are only a few drugs against coronavirus. Here we aimed to identify a cost-effective antiviral with broad spectrum activity and high safety profile.
Roca, Núria   +60 more
core   +1 more source

Building up cyclodextrins from scratch - templated enzymatic synthesis of cyclodextrins directly from maltose

open access: yes, 2021
Cyclodextrins (CDs) are commercially produced via enzymatic breakdown of starch or amylose. In contrast, we show that cyclodextrins can be synthesised directly from the disaccharide maltose in good yields by exploiting the use of templates to favour the ...
Larsen, Dennis   +3 more
core   +1 more source

Biological Studies on Cyclodextrins

open access: yes, 2020
In recent years, our knowledge of the biological effects of cyclodextrins has grown significantly. Cellular actions of cyclodextrins originate in their ability to form complexes with lipophilic biomolecules.
Ferenc Fenyvesi
core   +1 more source

Molecular insights to the anti-COVID-19 potential of α-, β- and γ-cyclodextrins

open access: yes, 2023
SARS-CoV-2 viral infection is regulated by the host cell receptors ACE2 and TMPRSS2, and therefore the effect of various natural and synthetic compounds on these receptors has recently been the subject of investigations.
Dharmender Gupta (17683406)   +8 more
core   +1 more source

Cyclodextrin in Vaccines: Enhancing Efficacy and Stability

open access: yesFuture Pharmacology, 2023
Cyclodextrins, a family of cyclic oligosaccharides, have received considerable interest in the field of pharmaceuticals due to their unique molecular structure and versatile properties.
Gamze Varan
doaj   +1 more source

Cyclodextrins as Multi-Functional Ingredients in Dentistry

open access: yesPharmaceutics, 2023
Cyclodextrins are present in a variety of oral hygiene compositions. The present work describes the role of cyclodextrins in several toothpastes and mouthwashes that are already available in the market, as well as their prospective use in other ...
Susana Santos Braga
doaj   +1 more source

Targeted Cyclodextrins.

open access: yes, 2011
Since 1970s cyclodextrins (CDs) and their derivatives, in virtue of their peculiar inclusion properties, have been proposed as pharmaceutical excipients and have found application in several marketed products.
SALMASO, STEFANO   +7 more
core   +1 more source

Dissolution Studies of Physical Mixtures of Indomethacin with Alpha- and Gamma-Cyclodextrins

open access: yesBiomolecules & Biomedicine, 2010
Oral administration of indomethacin has been limited by its poor water solubility. Cyclodextrins have been recognized as potential candidates to overcome the poor solubility of indomethacin through the formation of inclusion complexes.
Edina Vranić, Alija Uzunović
doaj   +1 more source

Cyclodextrin-Based Nanosponges: Overview and Opportunities

open access: yesFrontiers in Chemistry, 2022
Nanosponges are solid cross-linked polymeric nano-sized porous structures. This broad concept involves, among others, metal organic frameworks and hydrogels. The focus of this manuscript is on cyclodextrin-based nanosponges.
Gianluca Utzeri   +3 more
doaj   +1 more source

Direct Correlation between Complex Conformation and Chiral Discrimination upon Inclusion of Amino Acid Derivatives by β- and γ-Cyclodextrins

open access: yes, 2016
A correlation between the conformation and chiral recognition characteristics of a series of modified amino acid complexes with β- and γ-cyclodextrins has been determined, using titration microcalorimetry and 1H NMR techniques.
Yoshihisa Inoue (1271280)   +3 more
core   +1 more source

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