Results 21 to 30 of about 22,561 (204)

Ex Vivo Drug Screening Assay with Artificial Membranes: Characterizing Cholesterol Desorbing Competencies of Beta-Cyclodextrins

open access: yes, 2023
Despite advancements in contemporary therapies, cardiovascular disease from atherosclerosis remains a leading cause of mortality worldwide. Supported lipid bilayers (SLBs) are membrane interfaces that can be constructed with varying lipid compositions ...
Peter A. Chiarelli   +13 more
core   +1 more source

Galactosylation of Cyclodextrins and Branched Cyclodextrins by α-Galactosidases

open access: yesBioscience, Biotechnology, and Biochemistry, 1994
Transgalactosylated derivatives of cyclodextrins (CDs) and glucosyl and maltosyl CDs (G1- and G2-CDs) were synthesized by alpha-galactosidases from coffee bean and Mortierella vinacea (M. vinacea). The structures of the transfer products were analyzed by FAB-mass, 13C-NMR and methylation. Coffee bean alpha-galactosidase transferred a galactosyl residue
Hara, Koji   +6 more
openaire   +2 more sources

Melarsoprol cyclodextrin inclusion complexes as promising oral candidates for the treatment of human African trypanosomiasis [PDF]

open access: yes, 2011
Human African trypanosomiasis (HAT), or sleeping sickness, results from infection with the protozoan parasites <i>Trypanosoma brucei</i> (<i>T.b.</i>) <i>gambiense</i> or <i>T.b.rhodesiense</i> and is ...
Jones, A.   +35 more
core   +1 more source

Cyclodextrin in Vaccines: Enhancing Efficacy and Stability

open access: yesFuture Pharmacology, 2023
Cyclodextrins, a family of cyclic oligosaccharides, have received considerable interest in the field of pharmaceuticals due to their unique molecular structure and versatile properties.
Gamze Varan
doaj   +1 more source

Cyclodextrin nanofibers by electrospinning [PDF]

open access: yesChemical Communications, 2010
We have demonstrated that cyclodextrin (CD) (a non-polymeric system) can be electrospun into nanofibers by itself; methyl-beta-cyclodextrin (MbetaCD) nanofibers were electrospun and it was observed that the success of the electrospinning of the CD nanofibers strongly depends on (i) type of solvent, (ii) CD solution concentration and (iii ...
Celebioglu, A., Uyar, T.
openaire   +5 more sources

Phosphated cyclodextrins as water-soluble chiral NMR solvating agents for cationic compounds

open access: yesBeilstein Journal of Organic Chemistry, 2017
The utility of phosphated α-, β- and γ-cyclodextrins as water-soluble chiral NMR solvating agents for cationic substrates is described. Two sets of phosphated cyclodextrins, one with degrees of substitution in the 2–6 range, the other with degrees of ...
Cira Mollings Puentes, Thomas J. Wenzel
doaj   +1 more source

Cyclodextrins as Multi-Functional Ingredients in Dentistry

open access: yesPharmaceutics, 2023
Cyclodextrins are present in a variety of oral hygiene compositions. The present work describes the role of cyclodextrins in several toothpastes and mouthwashes that are already available in the market, as well as their prospective use in other ...
Susana Santos Braga
doaj   +1 more source

Cyclodextrin-Based Nanosponges: Overview and Opportunities

open access: yesFrontiers in Chemistry, 2022
Nanosponges are solid cross-linked polymeric nano-sized porous structures. This broad concept involves, among others, metal organic frameworks and hydrogels. The focus of this manuscript is on cyclodextrin-based nanosponges.
Gianluca Utzeri   +3 more
doaj   +1 more source

Cyclodextrins in Parkinson’s Disease [PDF]

open access: yesBiomolecules, 2018
Parkinson’s disease is a movement disorder characterized by a progressive degeneration of dopaminergic neurons that has been object of study by the scientific community through the last decades. However, nowadays there is still no treatment to cure it, although there are drugs available, with limited efficacy, to relieve the symptoms or replenish the ...
Barros, Marisa C. F.   +2 more
openaire   +4 more sources

Biological Studies on Cyclodextrins

open access: yes, 2020
In recent years, our knowledge of the biological effects of cyclodextrins has grown significantly. Cellular actions of cyclodextrins originate in their ability to form complexes with lipophilic biomolecules.
Ferenc Fenyvesi
core   +1 more source

Home - About - Disclaimer - Privacy