Results 31 to 40 of about 26,778 (245)

Entropy Effects in Intermolecular Associations of Crown-Ethers and Cyclodextrins with Amino Acids in Aqueous and in Non-Aqueous Media

Entropy, 2021
The analysis of the ratios of entropy and enthalpy characteristics and their contributions to the change in the Gibbs energy of intermolecular interactions of crown ethers and cyclodextrins with amino acids is carried out.
Tatyana Usacheva, Irina Terekhova, Diana Alister, Mikhail Agafonov, Natalya Kuranova, Dmitry Tyurin, Valentin Sharnin   +6 more
doaj   +1 more source

Investigation of the Interactions between the Hydrophobic Cavities of Cyclodextrins and Pullulanase

Molecules, 2011
The effects of cyclodextrins and derivatives on the activity and structure of pullulanase were investigated in this study. Our results showed that cyclodextrins and derivatives decreased the activity of pullulanase.
Zhengyu Jin, Bo Yu, Jinpeng Wang, Huanxin Zhang   +3 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Rapid Study on Mefloquine Hydrochloride Complexation with Hydroxypropyl-β-Cyclodextrin and Randomly Methylated β-Cyclodextrin: Phase Diagrams, Nuclear Magnetic Resonance Analysis, and Stability Assessment

Pharmaceutics, 2023
This study investigates the complexation of mefloquine hydrochloride by cyclodextrins to improve its solubility in order to design an oral solution.
Amaury Durand, David Mathiron, Sébastien Rigaud, Florence Djedaini-Pilard, Frédéric Marçon   +4 more
doaj   +1 more source

Protein‐Polymer Dynamic Hydrogels Utilizing Native Ligand Binding for Injectable Therapeutic Delivery and 3D Printing

Advanced Healthcare Materials, EarlyView.
Dynamic nanocolloidal hydrogels were synthesized via the co‐assembly of ligand‐modified spheroidal hyperbranched poly(glycerol) (HPG) and soluble albumin nanoparticles (SANs). Co‐assembly occurred through self‐association of the HPG, as well as its interaction with SANs via native ligand binding.
S. Cem Millik, Yonghui Wang, Kefan Song, Jessica M. Snyder, LeAnn Le, Lauren G. Brown, Shanny Hsuan Kuo, Ashleigh B. Theberge, Suzie H. Pun, Alshakim Nelson   +9 more
wiley   +1 more source

Topically Delivered Treg‐Attracting Microparticle‐Hydrogel Composites Recruit Regulatory T Cells and Limit Cardiac Injury After Severe Ischemia

Advanced Healthcare Materials, EarlyView.
CCL22‐releasing PLGA microparticles (MP) suspended in topically applied hydrogels (HEART) establish a sustained chemokine gradient at the injured myocardium. HEART recruits CCR4+ regulatory T cells, reduces infarct size and graft fibrosis, and improves cardiac function.
Matthew A. Borrelli, Alexis T. Reese, Jordan J. P. Warunek, Betsy Ann Varghese, Canxing Lin, Jeffery J. Baust, Brenda McMahon, Steven R. Little, Hēth R. Turnquist   +8 more
wiley   +1 more source

Recent progress in encapsulation and controlled release of pesticides based on cyclodextrin derivative carriers

Advanced Agrochem, 2022
In the context of the continuous increase in global grain production, accompanied by a large amount of investment in various pesticides, herbicides, fungicides, and other chemical pesticides.
Zhisheng Liu, Weiwei Xu, Elena G. Kovaleva, Jing Cheng, Haibing Li   +4 more
doaj   +1 more source

Cyclodextrins in Asymmetric and Stereospecific Synthesis

, 2015
Since their discovery, cyclodextrins have widely been used as green and easily available alternatives to promoters or catalysts of different chemical reactions in water.
Veaceslav Boldescu, Fliur Macaev
core   +1 more source

“Smelltronics”—From Gas to Smell Sensing

Advanced Materials, EarlyView.
The emerging field of smelltronics, encompassing sensing technologies for complex volatile organic compounds, holds significant potential for extracting valuable chemical information. It facilitates the noninvasive, real‐time monitoring of humans, food, and the environment.
Takeshi Ono, Tsunaki Takahashi, Jiangyang Liu, Haruka Honda, Zeng Jing, Wataru Tanaka, Takuro Hosomi, Takeshi Yanagida   +7 more
wiley   +1 more source

Polyanionic Cyclodextrin Induced Supramolecular Nanoparticle

Scientific Reports, 2016
Ionizable cyclodextrins have attracted increasing attention in host–guest chemistry and pharmaceutical industry, mainly due to the introduction of favorable electrostatic interactions. The ionizable cyclodextrins could not only enhance its own solubility
He-Lue Sun, Ying-Ming Zhang, Yong Chen, Yu Liu   +3 more
doaj   +1 more source