Faecal and urine metabolites, but not gut microbiota, may predict response to low FODMAP diet in irritable bowel syndrome [PDF]
, 2023 BackgroundThe low FODMAP diet (LFD) leads to clinical response in 50%–80% of patients with irritable bowel syndrome (IBS). It is unclear why only some patients respond.AimsTo determine if differences in baseline faecal microbiota or faecal and urine ...
Irving, Peter M. +8 more
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Acta Chimica Slovenica, 2020 A series of new solid esters was synthesized by using greener chemistry strategy involving simple reaction of an alcohol with sulfonamide ligand.
Muhammad Danish +5 more
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Microwave Spectroscopy of Cyclohexanecarboxylic Acid, Chlorosulfonic Acid, and Its Interaction with Water [PDF]
, 2021 This study combines computational chemistry and microwave spectroscopy to simulate the behavior of two molecules: cyclohexanecarboxylic acid and chlorosulfonic acid. In this thesis, cyclohexanecarboxylic acid will be observed on its own.
Rodriguez, Diego Erik
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Bulletin of the National Research Centre, 2021 Background The Himalaya hotspot, habitat to numerous indigenous species, harbours an endemic and endangered, cucurbit climber Herpetospermum darjeelingense (C.B.Clarke) H.Schaef. & S.S.Renner [Edgaria darjeelingensis C.B.Clarke]. Seeds of this plant have
Sourav Chakraborty +4 more
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Quinic Acid Derivatives as Inhibitors of Glucosyltransferase Si, A Virulence Factor of Streptococcus Mutans in The Pathogenesis of Dental Caries [PDF]
, 2023 The important prerequisite for the formation of dental caries is the ability of Streptococcus mutans to form the biofilm. It has been proved that the formation of biofilm is mediated mainly by the enzymatic action of the Glucosyltransferase (GTF) enzymes.
Kannan I +3 more
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A Novel Gβγ-Subunit Inhibitor Selectively Modulates μ-Opioid- Dependent Antinociception and Attenuates Acute Morphine-Induced Antinociceptive Tolerance and Dependence [PDF]
, 2008 The Gβγ subunit has been implicated in many downstream signaling events associated with opioids. We previously demonstrated that a small molecule inhibitor of Gβγ-subunit-dependent phospholipase (PLC) activation potentiated morphine-induced analgesia ...
Bidlack, Jean M +2 more
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Fermentation, 2023 Doramectin is a macrolide antiparasitic that is widely used in the treatment of mammalian parasitic diseases. Doramectin is usually produced by Streptomyces avermitilis fermentation using cyclohexanecarboxylic acid (CHC) as a precursor; however, the ...
Xiaojun Pan, Jun Cai
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Second-generation sulfonamide inhibitors of D-glutamic acid-adding enzyme: activity optimisation with conformationally rigid analogues of D-glutamic acid. [PDF]
, 2011 peer reviewedD-Glutamic acid-adding enzyme (MurD) catalyses the essential addition of d-glutamic acid to the cytoplasmic peptidoglycan precursor UDP-N-acetylmuramoyl-l-alanine, and as such it represents an important antibacterial drug-discovery target ...
Amoroso, Ana Maria +12 more
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Non-Natural Linker Configuration in 2,6-Dipeptidyl-Anthraquinones Enhances the Inhibition of TAR RNA Binding/Annealing Activities by HIV-1 NC and Tat Proteins [PDF]
, 2018 The HIV-1 nucleocapsid (NC) protein represents an excellent molecular target for the development of antiretrovirals by virtue of its well-characterized chaperone activities, which play pivotal roles in essential steps of the viral life cycle. Our ongoing
Caliendo, Giuseppe +16 more
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Antioxidants, 2023 Due to its high nutritional value and broad beneficial effects, the artichoke plant (Cynara cardunculus L.) is an excellent healthy food candidate.
Mirco Vacca +7 more
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