Results 71 to 80 of about 4,999,268 (231)

FDA‐approved drugs featuring macrocycles or medium‐sized rings

Archiv der Pharmazie, Volume 358, Issue 1, January 2025.
This review presents 17 macrocyclic drugs approved by the U.S. Food and Drug Administration during the past 5 years, highlighting their importance and critical role in modern therapeutics, and the innovative synthetic approaches for the construction of these macrocycles.
Youlong Du, Anas Semghouli, Qian Wang, Haibo Mei, Loránd Kiss, Daniel Baecker, Vadim A. Soloshonok, Jianlin Han   +7 more
wiley   +1 more source

Cobalt‐Mediated [3+1] Fragmentation of White Phosphorus: Access to Acylcyanophosphanides

Angewandte Chemie, Volume 136, Issue 6, February 5, 2024.
White phosphorus (P4) can be selectively activated and functionalized via low‐valent cobalt complexes. Subsequent treatment of the acylated P4 ligands with cyanide induces a rare [3+1] fragmentation and yields cyanophosphanides (P1) and triphosphido cobaltate (P3).
Sebastian Hauer, Thomas M. Horsley Downie, Gábor Balázs, Kai Schwedtmann, Jan J. Weigand, Robert Wolf   +5 more
wiley   +2 more sources

The conjugated process of carbon monoxide oxidation and cyclohexene hydrocarboxylation to cyclohexanecarboxylic acid

Тонкие химические технологии, 2014
The kinetic regularities of the conjugated process of the oxidation of carbon monoxide and the hydrocarboxylation of cyclohexene to cyclohexanecarboxylic acid have been studied.
E. A. Timashova, A. Yu. Putin, E. Yu. Bychkova, L. G. Bruk, O. N. Temkin, I. V. Oshanina   +5 more
doaj  

Carbonylation Reactions Using Single‐Atom Catalysts

ChemCatChem, Volume 16, Issue 24, December 20, 2024.
This minireview explores recent advances in tailoring solid supports for single‐atom catalysts (SACs) to enhance their catalytic performance in carbonylation reactions, including hydroformylation, methanol carbonylation, and oxidative carbonylation as the main reactions.
Lole Jurado, Sergio Posada‐Pérez, M. Rosa Axet   +2 more
wiley   +1 more source

Shikimic Acid Inhibits Osteoclastogenesis in Vivo and in Vitro by Blocking RANK/TRAF6 Association and Suppressing NF-κB and MAPK Signaling Pathways

Cellular Physiology and Biochemistry, 2018
Background/Aims: Bone homeostasis is associated with the balance between bone-resorbing osteoclasts and bone-forming osteoblasts. Unbalanced bone homeostasis as a result of reduced osteogenesis or excessive osteoclastogenesis can lead to disorders such ...
Xiao Chen, Xiaoqun Li, Xiao Zhai, Xin Zhi, Liehu Cao, Longjuan Qin, Jiacan Su   +6 more
doaj   +1 more source

Pembuatan Biodiesel Dari Minyak Nyamplung (Calophyllum Inophyllum L) Dengan Reaksi Transesterifikasi Menggunakan Katalis K2O/H-Za Berbasis Zeolit Alam [PDF]

, 2013
Kebutuhan dunia akan minyak bumi telah mencapai 10.000 juta ton pertahun. Eksploitasi secara berlebihan dan berkepanjangan mengakibatkan cadangan minyak bumi terus berkurang, dimana hal tersebut dapat diatasi dengan sumber energi alternatif terbarukan ...
Gunardi, I. (Ignatius), Mayangsari, W. (Wahyu), Permatasari, A. (Archita)   +2 more
core   +1 more source

KAEMPFEROL-3-O-SAMBUBIOSIDE DARI BUNGA Hibiscus sabdariffa MAMPU MENGHAMBAT PROTEIN BINDING GALACTOSE (LecA) DAN TRANSCRIPTIONAL ACTIVATOR (LasR) Pseudomonas aeruginosa : STUDI IN SILICO [PDF]

, 2022
ABSTRAK Pendahuluan: Infeksi nosokomial karena P. aeruginosa terjadi akibat pembentukan adhesi dan biofilm yang diperantarai protein binding galactose (LecA) dan transcriptional activator LasR. Senyawa aktif bunga H.
Bintari, Yoni Rina, Mochsen, Iqbal Ismail, Risandiansyah, Rio   +2 more
core   +1 more source

Spring nitrogen and plant growth regulator effects on seed yield of orchardgrass

Crop Science, Volume 64, Issue 6, Page 3533-3540, November/December 2024.
Abstract Orchardgrass (Dactylis glomerata L.) is an important forage seed crop, but unlike other cool‐season grasses, seed yields have not increased over time. Seed yield increases in orchardgrass may be possible with plant growth regulators (PGRs) such as trinexapac‐ethyl (TE) and chlormequat chloride (CCC).
Nicole P. Anderson, Mohammed M. Morad, Thomas G. Chastain   +2 more
wiley   +1 more source

Prophylactic tranexamic acid for reducing blood loss in pregnant females undergoing cesarean section: A systematic review and meta‐analysis

Journal of Obstetrics and Gynaecology Research, Volume 50, Issue 9, Page 1439-1458, September 2024.
Abstract Objective We aim to assess the efficacy of prophylactic tranexamic acid (TXA) in reducing blood loss after cesarean section (CS). Methods We systematically searched PubMed and Embase for randomized controlled trials published between 1990 and 2023 to conduct a meta‐analysis on adult women undergoing CS and receiving prophylactic TXA.
Ammar Al Naimi, Haobo Ma, Abarna Pearl, Greg Yungtum, Valluvan Rangasamy   +4 more
wiley   +1 more source

The Itinerant Position of Yttrium as Evidenced by Carboxylic Acid Extractions [PDF]

, 2012
The rare-earth elements Y and La-Lu share many similar physical and chemical properties. These similarities are reflected by the difficulty in the complete separation of the rare earths, often requiring hundreds to thousands of stages for the production ...
Collier, Dustin C
core   +1 more source