Results 91 to 100 of about 2,071 (135)

Pharmacokinetics and pharmacodynamics of valproate analogs in rats. II. Pharmacokinetics of octanoic acid, cyclohexanecarboxylic acid, and 1‐methyl‐1‐cyclohexanecarboxylic acid

Biopharmaceutics & Drug Disposition, 1993
AbstractThe pharmacokinetics of valproic acid (VPA) and three structural analogs, octanoic acid (OA), cyclohexanecarboxylic acid (CCA), and 1‐methyl‐1‐cyclohexanecarboxylic acid (MCCA), were examined in female Sprague‐Dawley rats. All four carboxylic acids evidenced dose‐dependent disposition.
M J, Liu, G M, Pollack
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The metabolism of cyclohexanecarboxylic acid and 3-cyclohexenecarboxylic acid by Pseudomonas putida

Canadian Journal of Microbiology, 1982
A strain of Pseudomonas putida grew rapidly on cyclohexanecarboxylic acid as a sole source of carbon. A CoA-mediated β-oxidation pathway was induced for the metabolism of the compound. The organism could not utilize 3-cyclohexenecarboxylic acid as a sole source of carbon for growth, but cells grown on gluconate in the presence of 3 ...
Blakley, E. R., Papish, B.
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The metabolism of cyclohexanecarboxylic acid in phaseolus vulgaris

Phytochemistry, 1970
Abstract Cyclohexanecarboxylic acid is converted to 1-cyclohexanecarbonyl-β- d -glucose and N -cyclohexanecarbonyl- l -aspartic acid when administered to leaf disks of Phaseolus vulgaris in the light.
J.G. Severson, B.A. Bohm, C.E. Seaforth
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The Metabolism of Cyclohexanecarboxylic Acid in the Isolated Perfused Rat Liver

Xenobiotica, 1977
1. Cyclohexanecarboxylic acid in isolated perfused rat livers was eliminated from the perfusion system by a first-order process. 2. After 6 h, 16% was excreted in bile as cyclohexylcarbonyl beta-D-glucuronide. The remainder was present in the perfusate as unchanged cyclohexanecarboxylic acid (10%), hippuric acid (50%), hexahydrohippuric acid (2%), 3,4 ...
D, Brewster, R S, Jones, D V, Parke
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Pharmacokinetics and Pharmacodynamics of Valproate Analogues in Rats. IV. Anticonvulsant Action and Neurotoxocity of Octanoic Acid, Cyclohexanecarboxylic Acid, and 1‐Methyl‐1 ‐Cyclohexanecarboxylic Acid

Epilepsia, 1994
Summary: We examined the pharmacodynamics of valproate (VPA) and three structural analogues, octanoic acid (OA), cyclohexanecarboxylic acid (CCA), and 1‐methyl‐1‐cyclohexanecarboxylic acid (MCCA) in rats. A pentylenetetrazol (PTZ) infusion seizure model was used to determine threshold convulsive doses of PTZ; the increase in PTZ threshold dose after ...
M J, Liu, G M, Pollack
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The aromatization of cyclohexanecarboxylic acid to hippuric acid: substrate specificity and species differences

Molecular and Cellular Biochemistry, 1985
The ability to convert cyclohexanecarboxylic acid to hippuric acid has been studied in liver from guinea pigs, rabbits, rats and mice using a gas chromatographic - mass spectrometric method employing selected ion monitoring. Guinea pig liver showed the highest activity, giving values double of those found in rabbit liver and five times those in rat ...
A M, Svardal, R R, Scheline
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Kinetics and mechanism of coupled synthesis of cyclohexanecarboxylic acid

Russian Journal of Physical Chemistry A, 2015
The effect of the nature of the anion in a palladium salt on a coupled process involving the oxidation of CO and hydrocarboxylation of cyclohexene in the PdX2-CuBr2-THF-H2O system was studied. The kinetics was investigated under the steady-state conditions.
A. Yu. Putin, E. Yu. Bychkova, K. V. Trunilina, A. Yu. Zakgeim, E. A. Katsman, O. N. Shishilov, N. S. Akhmadullina, I. V. Oshanina, O. N. Temkin, L. G. Bruk   +9 more
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Diversions of the Shikimate Pathway — The Biosynthesis of Cyclohexanecarboxylic Acid

1992
The shikimic acid pathway1 has evolved in plants and microorganisms to provide for the synthesis of the aromatic amino acids, phenylalanine, tyrosine and tryptophan, as well as a number of other essential aromatic compounds, e.g., jo-aminobenzoic acid, the precursor of folic acid, or]D-hydroxybenzoic acid, the precursor of ubiquinone.
H. G. Floss, H. Cho, R. Casati, K. A. Reynolds, E. Kennedy, B. S. Moore, J. M. Beale, U. M. Mocek, K. Poralla   +8 more
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ChemInform Abstract: MIXED ANHYDRIDES OF CYCLOHEXANECARBOXYLIC ACID WITH SULPHONIC ACIDS

Chemischer Informationsdienst, 1974
AbstractDas durch Pyrolyse von Cyclohexancarbonsäureanhydrid erhaltene" Pentamethylenketen (I) reagiert mit den Sulfonsäuren (II) zu den gemischten Anhydriden (III), die als Acylierungsmittel geeignet sind, wie am Beispiel ihrer Umsetzung mit β‐Naphthol zu dem Ester (IV) (98, 91 bzw. 89% Ausbeute) bewiesen wird.
EZIO TEMPESTI, LUIGI GIUFFRE, GIANCARLO SIOLI, MIRCO FORNAROLI, GIUSEPPI AIROLDI   +4 more
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Biosynthetic studies on ansatrienin A. Formation of the cyclohexanecarboxylic acid moiety

Journal of the American Chemical Society, 1993
The formation of the cyclohexanecarboxylic acid moiety in the biosynthesis of ansatrienin (mycotrienin) has been studied. [sup 13]C- and [sup 2]H-labeled samples of shikimic acid were used to probe the stereochemistry of processing the cyclohexane ring of shikimic acid and to establish the fate of all the precursor hydrogens in this transformation.
Bradley S. Moore, Hyeongjin Cho, Rosangela Casati, Eileen Kennedy, Kevin A. Reynolds, Ursula Mocek, John M. Beale, Heinz G. Floss   +7 more
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