Stereodivergent Access to Aliphatic Nitro Compounds Bearing Multi-Contiguous Stereocenters via Sequential Catalysis. [PDF]
Adv Sci (Weinh)Herein, we report a highly efficient synthesis of aliphatic nitro compounds bearing multi‐contiguous stereocenters in good yields with excellent diastereo‐ and enantio‐selectivities by combining copper‐catalyzed asymmetric conjugate addition of dialkylzinc reagents to nitroalkenes with iridium‐catalyzed asymmetric allylic substitution reaction ...
Xie JH, Hou YM, Wu ZJ, Zheng C, You SL.
europepmc +2 more sources
Efficient methods for enol phosphate synthesis using carbon-centred magnesium bases [PDF]
, 2015 Efficient conversion of ketones into kinetic enol phosphates under mild and accessible conditions has been realised using the developed methods with di-tert-butylmagnesium and bismesitylmagnesium.
Kerr, William J. +3 more
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Enantio- and Diastereoconvergent Cyclocondensation Reactions: Synthesis of Enantiopure cis-Decahydroquinolines. [PDF]
, 2016 Up to four stereocenters with a well-defined configuration are generated in a single synthetic step by the cyclocondensation of (R)-phenylglycinol or (1S,2R)-1-amino-2-indanol with stereoisomeric mixtures (racemates, meso forms, diastereoisomers) of ...
Amat Tusón, Mercedes +6 more
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ChemistryOpen, 2019 The performance of density functionals and wavefunction methods for describing the thermodynamics and kinetics of hydride reductions of 2‐substituted cyclohexanones has been evaluated for the first time.
Xavier Deraet +5 more
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Molecules, 2017 For the first time, arylmethylidene cyclohexanones that are non-symmetrical due to the presence of peripheral substituents were studied in 1,3-dipolar cycloaddition reactions.
Alexander Anis’kov +3 more
doaj +1 more source
Camphor pathway redux: functional recombinant expression of 2,5- and 3,6-diketocamphane monooxygenases of Pseudomonas putida ATCC 17453 with their cognate flavin reductase catalyzing Baeyer-Villiger reactions [PDF]
, 2013 Whereas the biochemical properties of the monooxygenase components that catalyze the oxidation of 2,5-diketocamphane and 3,6-diketocamphane (2,5-DKCMO and 3,6-DKCMO, respectively) in the initial catabolic steps of (+) and (−) isomeric forms of camphor ...
Bergeron Helene +7 more
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Synthesis of ketones from biomass-derived feedstock
Nature Communications, 2017 Conversion of biomass-derived chemicals to industrially relevant products can allow sustainable production of organic compounds. Here the authors report that aromatic ethers, which can be derived for biomass, can be converted into various cyclohexanones ...
Qinglei Meng +4 more
doaj +1 more source
Molecules, 2003 The reaction of 3-phenyl-2,4-diacetyl(diethoxycarbonyl)-5-hydroxy-5-methylcyclohexanones with ethanolamine and ethylene glycol proceeds regioselectively using the carbonyl group of the alicycle to produce the corresponding cyclohexenylethanolamines and ...
Vitaly V. Sorokin +3 more
doaj +1 more source
Reactive organoallyl species generated from aryl halides and allene: allylation of alpha,beta-unsaturated aldehydes and cyclic ketones employing Pd/In transmetallation processes [PDF]
, 2008 Allylation of α,β-unsaturated aldehydes and cyclic ketones promoted by Pd/In transmetallation processes has been studied. The unsaturated aldehydes underwent regioselective 1,2-addition to afford secondary homoally alcohols.
Anwar +56 more
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Chiral Sulfinamide/Achiral Sulfonic Acid Cocatalyzed Enantioselective Protonation of Enol Silanes [PDF]
, 2011 The application of chiral sulfinamides and achiral sulfonic acids as a co-catalyst system for enantioselective protonation reactions is described. Structurally simple, easily accessible sulfinamides were found to induce moderate-to-high eeʼs in the ...
Beck, Elizabeth M. +2 more
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