Results 11 to 20 of about 4,036 (208)

Radical-mediated C-C cleavage of unstrained cycloketones and DFT study for unusual regioselectivity

Nature Communications, 2020
C-C bond scission of unstrained cycloketones with high regioselectivity is a challenging synthetic task. Here, the authors show a facile C-C cleavage of cyclohexanones and cyclopentanones with unusual selectivity under mild conditions with the aid of an ...
Mingyang Wang, Man Li, Shan Yang, Xiao-Song Xue, Xinxin Wu, Chen Zhu   +5 more
doaj   +1 more source

Enantio- and Diastereoconvergent Cyclocondensation Reactions: Synthesis of Enantiopure cis-Decahydroquinolines. [PDF]

, 2016
Up to four stereocenters with a well-defined configuration are generated in a single synthetic step by the cyclocondensation of (R)-phenylglycinol or (1S,2R)-1-amino-2-indanol with stereoisomeric mixtures (racemates, meso forms, diastereoisomers) of ...
Amat Tusón, Mercedes, Bosch Cartes, Joan, Ghirardi, Elena, Griera Farres, Rosa, Llor Brunés, Núria, Molins i Grau, Elies, Navío, Laura   +6 more
core   +1 more source

One-pot and metal-free synthesis of 3-arylated-4-nitrophenols via polyfunctionalized cyclohexanones from β-nitrostyrenes

Beilstein Journal of Organic Chemistry, 2020
β-Nitrostyrenes underwent a Diels–Alder reaction with Danishefsky’s diene to afford cyclohexenes together with the corresponding hydrolyzed products, 3-arylated-5-methoxy-4-nitrocyclohexanones.
Haruyasu Asahara, Minami Hiraishi, Nagatoshi Nishiwaki   +2 more
doaj   +1 more source

Reactive organoallyl species generated from aryl halides and allene: allylation of alpha,beta-unsaturated aldehydes and cyclic ketones employing Pd/In transmetallation processes [PDF]

, 2008
Allylation of α,β-unsaturated aldehydes and cyclic ketones promoted by Pd/In transmetallation processes has been studied. The unsaturated aldehydes underwent regioselective 1,2-addition to afford secondary homoally alcohols.
Anwar, Araki, Araki, Araki, Araki, Brase, Cacchi, Chan, Cleghorn, Cleghorn, Cooper, Cooper, Cooper, Denmark, Dupont, Fontana, Gai, Gomez, Grigg, Han, Hirashita, Hopkins, Howell, Kang, Kimura, Kless, Knodler, Larock, Laura A.T. Cleghorn, Law, Lee, Li, Littke, Liu, Marshall, Milena Simic, Miles, Miura, Miyabe, Nakahara, Norsikian, Ohno, Pardoe, Parrill, Podlech, Quan, Ronald Grigg, Sole, Tamaru, Tang, Tietze, Tsuji, Vladimir Savic, Wang, Zanoni, Zanoni, Zhou   +56 more
core   +2 more sources

A Benchmark of Density Functional Approximations For Thermochemistry and Kinetics of Hydride Reductions of Cyclohexanones

ChemistryOpen, 2019
The performance of density functionals and wavefunction methods for describing the thermodynamics and kinetics of hydride reductions of 2‐substituted cyclohexanones has been evaluated for the first time.
Xavier Deraet, Tatiana Woller, Ruben Van Lommel, Prof. Frank De Proft, Prof. Guido Verniest, Prof. Mercedes Alonso   +5 more
doaj   +1 more source

Sulfur‐Directed Construction of Vinyl Cyclopropanes from 1,3‐Dienes

Angewandte Chemie, EarlyView.
Sulfur takes control. A pending thioether acts as a molecular compass, directing carbene addition to the 1,3‐diene scaffold with exceptional regio‑ and diastereocontrol to forge sulfur‐substituted vinyl cyclopropanes (S‐VCPs) — molecular architectures inaccessible via conventional cyclopropanation strategies.
Anna Keimer, Jonas Rettig, Tim‐Niclas Streit, Bob Barthel, Mélissa Calmels, Moritz Malischewski, Franz‐Lucas Haut   +6 more
wiley   +2 more sources

Synthesis of ketones from biomass-derived feedstock

Nature Communications, 2017
Conversion of biomass-derived chemicals to industrially relevant products can allow sustainable production of organic compounds. Here the authors report that aromatic ethers, which can be derived for biomass, can be converted into various cyclohexanones ...
Qinglei Meng, Minqiang Hou, Huizhen Liu, Jinliang Song, Buxing Han   +4 more
doaj   +1 more source

A Diastereoselective Synthesis of Dispiro[oxindole-cyclohexanone]pyrrolidines by 1,3-Dipolar Cycloaddition

Molecules, 2017
For the first time, arylmethylidene cyclohexanones that are non-symmetrical due to the presence of peripheral substituents were studied in 1,3-dipolar cycloaddition reactions.
Alexander Anis’kov, Irina Klochkova, Roman Tumskiy, Alevtina Yegorova   +3 more
doaj   +1 more source

Efficient methods for enol phosphate synthesis using carbon-centred magnesium bases [PDF]

, 2015
Efficient conversion of ketones into kinetic enol phosphates under mild and accessible conditions has been realised using the developed methods with di-tert-butylmagnesium and bismesitylmagnesium.
Kerr, William J., Lindsay, David M., Patel, Vipulkumar K., Rajamanickam, Muralikrishnan   +3 more
core   +1 more source

Continuous production of biorenewable, polymer-grade lactone monomers through Sn-β-catalyzed baeyer-villiger oxidation with H2 O2 [PDF]

, 2017
The Baeyer-Villiger oxidation is a key transformation for sustainable chemical synthesis, especially when H2O2 and solid materials are employed as oxidant and catalyst, respectively.
Al-Nayili, Baeyer, Boronat, Cavani, Chai, Conrad, Corma, Corma, Criegee, Dijkmans, Gambarotti, Grimme, Hammond, Hammond, Hammond, Hiljanen-Vainio, Imada, Li, Llevot, Lowe, Padovan, Park, Pérez-Ramírez, Quilter, Reyes, Scalmani, Schutyser, Vilela, Wang, Watts, Yakabi, Zhao   +31 more
core   +1 more source