Results 71 to 80 of about 2,800 (171)

Comprehensive in vitro profiling of traditional and emerging stimulants at monoamine transporters and the 5‐HT2A receptor

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 19, Page 5871-5894, October 2026.
A pharmacological profiling of 58 synthetic stimulants of various classes at dopamine, norepinephrine, and serotonin transporters and the 5‐HT2A receptor, most showing distinct class‐dependent profiles, with some indicating a high abuse potential. Background and Purpose New psychoactive substances (NPSs) often emerge on the illicit drug market with ...
Darta Stalberga   +9 more
wiley   +1 more source

Hindered organoboron groups in organic synthesis 16. preparation and use of lithium ditripylethylhydroborate for the diastereoselective reduction of cyclohexanones

open access: yes, 1991
Preparations of lithium and potassium ditripylethylhydroborates are outlined. The lithium salt reduces substituted cyclohexanones with diastereoselectivities comparable with the most selective reagents known, but with the advantages that low temperatures
Pelter, A., Smith, Keith, Norbury, A.
core   +1 more source

Toward the Synthesis of Pestalustaine A: Structural Revision and Formation of Original Strained Tricyclic Architectures

open access: yesAngewandte Chemie, Volume 138, Issue 37, 7 September 2026.
Our synthetic endeavor toward the total synthesis of the reported unprecedented tricyclic skeleton of the sesquiterpene pestalustaine A allowed us to perform divergent cyclizations of a bicyclo[4.4.1]undec‐3‐ene into complex tricyclic architectures and to revise the structure of the natural product.
Wei Cao   +12 more
wiley   +2 more sources

Fabrication of Silicon–Ceramic (SiCer) Composite Multilayer Modules With Embedded NTC Thermistor Sensors

open access: yesInternational Journal of Applied Ceramic Technology, Volume 23, Issue 5, October 2026.
• Integration of functional materials in silicon–ceramic (SiCer) composite multilayer substates is demonstrated. • We developed the cofiring of Ni–Mn–Zn–Co‐based thermistor formulations and BCT6 LTCC tapes. • Integration of printed NTC thermistor films in LTCC and SiCer multilayer architectures ABSTRACT Silicon–ceramics composite substrates (SiCer) are
Manuel Heidenreich   +5 more
wiley   +1 more source

π‐Extended Silyl Enolates as Emerging Platforms in Radical Chemistry

open access: yesEuropean Journal of Organic Chemistry, Volume 29, Issue 36, 24 September 2026.
This review covers the emerging role of π‐extended silyl polyenol ethers in radical chemistry. It highlights their versatile roles as electron‐rich SOMOphiles, silyl radical cation precursors, and nucleophilic partners in radical–polar crossover manifolds, while considering recent advances in photoredox catalysis, electrochemistry, and transition metal‐
Debora Guazzetti   +3 more
wiley   +1 more source

Photochemical Ring Opening of Cyclopropyl Silyl Ethers Enables β–β Coupling, Radical‐Polar Crossover and Annulation

open access: yesAngewandte Chemie, Volume 138, Issue 37, 7 September 2026.
A photochemical platform enables β–β coupling of cyclopropyl silyl ethers with electron‐deficient alkenes. The resulting adducts serve as entry points into annulative and radical–polar crossover pathways, providing rapid access to fused, bridged, and spirocyclic architectures, including late‐stage scaffold diversification to diterpene‐like carbocyclic ...
Jacop Rydén   +5 more
wiley   +2 more sources

Remapping the Synthetic Landscape of α‐Tertiary Alkylamines via Dual‐Functional Catechol

open access: yesAngewandte Chemie, Volume 138, Issue 37, 7 September 2026.
A three‐component assembly strategy has been developed for the modular synthesis of hindered α‐tertiary aliphatic amines from readily available precursors through unlocking the dual role of catechol. The practicality of this methodology has been demonstrated in over 90 examples, including compounds that are otherwise difficult to access, along with ...
Chen‐Yan Cai, Yuzuru Kanda, Tian Qin
wiley   +2 more sources

External Chiral Ligand-Mediated Enantioselective Peterson Reaction of α-Trimethylsilanylacetate with Substituted Cyclohexanones

open access: yes, 2016
The asymmetric Peterson reaction of an α-trimethylsilanylacetate with 4-substituted and 3,5-disubstituted cyclohexanones was mediated by an external chiral tridentate ligand to give the corresponding olefins with an axial chirality in high yields and ...
Mayu Iguchi (2716744)   +1 more
core   +1 more source

Titanium‐Catalyzed Diastereoselective Keto‐ and Iminonitrile Cyclizations

open access: yesChemistry – A European Journal, Volume 32, Issue 35, 19 September 2026.
The titanium(III)‐catalyzed diastereoselective cyclization of readily‐available substituted ketonitriles gives cyclopentanones in good yield and stereoselectivity. Subsequent 1,2‐addition allows the preparation of cyclopentyls with three consecutive stereocenters.
Christoph Kern   +4 more
wiley   +1 more source

Palladium-Catalyzed [1,3]-O-to-C Rearrangement of Pyrans toward Functionalized Cyclohexanones

open access: yes, 2016
Functionalized cyclohexanones are prepared from cyclic enol ethers via a Pd-catalyzed [1,3]-O-to-C rearrangement reaction. α-Arylketones are generated with excellent diastereocontrol when basic phosphine ligands are used.
Julien C. R. Brioche (2254657)   +4 more
core   +1 more source

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