Results 51 to 60 of about 4,036 (208)

The search for tolerant Lewis acid catalysts. Part2: enantiopure cycloalkyldialkylsilyl triflimide catalysts [PDF]

, 2007
A series of 2-aryl-and arylmethyl-3-dialkylphenylsilyl cycloalkanones have been prepared and resolved. The pure enantiomers were reduced to the corresponding cycloalkane derivatives.
Dive, Georges, Ghosez, Léon, Mathieu, Benoît, Tang Zilong,, Tinant, Bernard   +4 more
core   +1 more source

1,2‐Diazetidines − Structure, Synthesis, and Functionalization

European Journal of Organic Chemistry, EarlyView.
1,2‐Diazetidines are saturated four‐membered heterocycles featuring two adjacent nitrogen atoms. Despite recent advances in their synthesis and promising potential in medicinal chemistry, the chemistry of these cyclic hydrazines remains underexplored.
Stefan Roesner
wiley   +1 more source

Identification and evaluation of antiviral activity of novel compounds targeting SARS-CoV-2 virus by enzymatic and antiviral assays, and computational analysis

Journal of Enzyme Inhibition and Medicinal Chemistry
The viral genome of the SARS-CoV-2 coronavirus, the aetiologic agent of COVID-19, encodes structural, non-structural, and accessory proteins. Most of these components undergo rapid genetic variations, though to a lesser extent the essential viral ...
Ivana Nemčovičová, Katarína Lopušná, Iveta Štibrániová, Fabio Benedetti, Federico Berti, Fulvia Felluga, Sara Drioli, Mattia Vidali, Jaroslav Katrlík, Lucia Pažitná, Alena Holazová, Jana Blahutová, Simona Lenhartová, Monika Sláviková, Boris Klempa, Miroslav Ondrejovič, Daniela Chmelová, Barbora Legerská, Stanislav Miertuš, Mária Klacsová, Daniela Uhríková, Lukáš Kerti, Vladimír Frecer   +22 more
doaj   +1 more source

Catalytic Asymmetric Transfer Hydrogenation of Imines: Recent Advances [PDF]

, 2015
In this review article recent developments in the asymmetric transfer hydrogenation of imines from 2008 up to today are presented. The main methodology involves either metal-catalyzed procedures in the presence of a chiral ligand or organocatalyzed ...
Foubelo, Francisco, Yus, Miguel
core   +2 more sources

Divergent Synthesis of Polycyclic Derivatives via Gold Catalysis

European Journal of Organic Chemistry, EarlyView.
Gold(I)‐catalyzed cycloisomerization enables the formation of complex 3D structures from simple enyne precursors. This study presents a divergent strategy to synthesize functionalized bicyclic and tricyclic scaffolds from a common alkynyl ketone.
Emilie Gentilini, Vincent Davenel, Pierre Ligonès, Jean‐Marie Fourquez, Véronique Michelet   +4 more
wiley   +1 more source

Strategies for the synthesis of enantiopure compounds focused on organocatalysis [PDF]

, 2012
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/32393The preparation of enantiomerically pure compounds (EPC) is a continuous social demand due to the clinical advantages that enantiopure drugs offer over the racemic forms. Here, the best
Arróniz, Carlos, Escolano Mirón, Carmen   +1 more
core  

Mapping the internal recognition surface of an octanuclear coordination cage using guest libraries [PDF]

, 2014
Size and shape criteria for guest binding inside the cavity of an octanuclear cubic coordination cage in water have been established using a new fluorescence displacement assay to quantify guest binding.
Adams H., Adriaenssens L., Ajami D., Ajami D., Ajami D., Alvarez S., Amenta V., Amenta V., Amenta V., Amouri H., Amouri H., Ams M. R., Andrews P. R., Asadi A., Barry N. P. E., Bolliger J. L., Bradshaw D., Breiner B., Brown C. J., Browne C., Brumaghim J. L., Buurma N. J., Chakrabarty R. J., Chang J. C., Chekmeneva E., Christopher A. Hunter, Cisse L., Clever G. H., Clever G. H., Clever G. H., Coles S. J., Collet A., Comby S., Conn M. M., Corbellini F., Cram D. J., Cram D. J., Cram D. J., Custelcean R., Desmarets C., Dolomanov O. V., Fiedler D., Fujita M., Galan A., Ha J.-H., Hamilton T. D., Han M., Harris K., Hastings C. J., Hastings C. J., Hatakeyama Y., Hof F., Hooley R. J., Horiuchi S., Houk K. N., Hummer G., Hunter C. A., Hunter C. A., Hunter C. A., Hunter C. A., Hunter C. A., Hunter C. A., Ichihara H., Inokuma Y., Inokuma Y., Inokuma Y., Jiang W., Jin P., Jinks M. A., Kawano M., Kerckhoffs J. M. C. A., Kishi N., Kishi N., Kopilevich S., Laughrey Z., Lewis J. E. M., Livingstone J. R., Mal P., Martina Whitehead, Mecozzi S., Metherell A. J., Meyer E. A., Michael D. Ward, Moerkerke S., Murase T., Nakamura T., Nassimbeni L. R., Nau W. M., Nishioka Y., O’Neil E. J., Perry J. J., Pluth M. D., Pratt L. R., Purse B. W., Rebek J., Rebek J., Reynolds J. A., Rieth S., Ronson T. K., Samanta D., Sawada T., Seidel S. R., Serrano L., Serrano L., Sheldrick G. M., Shenoy S. R., Sherman J. C., Simon Turega, Slovak S., Smulders M. M. J., Smulders M. M. J., Snyder P. W., Southall N. T., Spolar R. S., Spolar R. S., Spolar R. S., Sun H., Takano K., Tanford C., Therrien B., Tidmarsh I. S., Turega S., Turega S., Vallone B., Vannoy C. H., Ward M. D., Ward M. D., Whitehead M., William Cullen, Williams A. F., Yamauchi Y., Yi J. W., Yoshizawa M., Yoshizawa M., Yoshizawa M., Yoshizawa M.   +135 more
core   +3 more sources

Solubilities of CL‐20 and MDNT in Organic Solvents for Technical Cocrystallization

Propellants, Explosives, Pyrotechnics, EarlyView.
ABSTRACT The 1:1 molar cocrystal of 2,4,6,8,10,12‐hexanitro‐2,4,6,8,10,12‐hexaazaisowurtzitane (CL‐20) and 1‐methyl‐3,5‐dinitro‐1,2,4‐triazole (MDNT) is reported to show a detonation velocity 100 m/s faster than β‐HMX. To establish a scalable synthesis method, the solubility of ε‐CL‐20 and MDNT was investigated.
Eduard Wegert, Peter Schultz, Thomas M. Klapötke   +2 more
wiley   +1 more source

Vibrational Excitons in CH-Stretching Fundamental and Overtone Vibrational Circular Dichroism Spectra [PDF]

, 2005
A set of vibrational circular dichroism (VCD) spectra in the CH-stretching fundamental region for about twenty compounds belonging to the class of essential oils was empirically analyzed by the use of a sort of vibrational exciton mechanism, involving ...
ABBATE S, GANGEMI R, LAUX L, LEBON F, LONGHI G   +4 more
core   +1 more source

Ligand‐Controlled Tunable Distal C(sp2)–H Functionalization of Aryl and Benzyl Phosphonates

Transformative Chemistry, EarlyView.
The switchable borylation of aryl and benzyl phosphonates with good to excellent regioselectivity was demonstrated. Through orthogonal transformation of Horner–Wadsworth–Emmons olefination and Suzuki–Miyaura cross coupling, a variety of styrene derivatives were obtained with precise site control.
Han Ang, Yajun Wang, Jiawei Ma, Shengmeng Qin, Shuo Lu, Wenju Chang, Yong Liang   +6 more
wiley   +1 more source