Results 61 to 70 of about 1,766 (177)

Pharmaceuticals Made with Hydrogen: A Sustainable and Efficient Approach Using Flow Synthesis

open access: yesChemistry – A European Journal, Volume 32, Issue 28, 25 July 2026.
We demonstrate a sustainable strategy for pharmaceutical manufacturing by combining hydrogen, heterogeneous catalysis, and continuous flow synthesis. The development of novel catalysts and their application in a multi‐step synthesis of donepezil enabled a highly productive process with no intermediate purification.
Shū Kobayashi, Haruro Ishitani
wiley   +1 more source

A Hoveyda–Grubbs‐Type Olefin Metathesis Catalyst Bearing a Fluorinated Unsymmetrical NHC Ligand

open access: yesEuropean Journal of Inorganic Chemistry, Volume 29, Issue 21, 25 July 2026.
A fluorinated unsymmetrical NHC ruthenium complex was synthesised and employed as a catalyst for olefin metathesis reactions. The modification of the steric and electronic properties of the NHC ligand through the introduction of fluorine substituents results in improved activity but lower selectivity compared to the analogous non‐fluorinated NHC ...
Rubina Troiano   +3 more
wiley   +1 more source

Lithium tri-sec-butylborodeuteride: a new reagent for the stereoselective deuterium addition to cyclohexanones with single chair conformations

open access: yesARKIVOC, 2001
Peter Gärtner   +3 more
doaj   +1 more source

To PLP or Not to PLP: Stereodivergent Transaminase-Catalyzed Reactions Directed by Kinetic and Thermodynamic Control. [PDF]

open access: yesJ Org Chem
Fitzgerald MJ   +8 more
europepmc   +1 more source

Cascade Grignard Addition: Propargyl Claisen Rearrangement for the Stereoselective Synthesis of α-Allene Quaternary Centers in Cyclohexanones. [PDF]

open access: yesOrg Lett
Armendariz-Gonzalez E   +8 more
europepmc   +1 more source

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