Results 81 to 90 of about 23,800,079 (261)
The Role of PPARgamma in the Cyclooxygenase Pathway in Lung Cancer. [PDF]
, 2008 Decreased expression of peroxisome proliferator activated receptor-gamma (PPARgamma) and high levels of the proinflammatory enzyme cyclooxygenase-2 (COX-2) have been observed in many tumor types.
Dubinett, Steven M +4 more
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Arquivos de Gastroenterologia, 2008 BACKGROUND: Crohn's disease accompanied by nonspecific or idiopathic ulcerative proctocolitis corresponds to a condition called intestinal inflammatory disease.
Mônica Romero +5 more
doaj +1 more source
Cyclooxygenase in biology and disease [PDF]
, 1998 Cyclooxygenase (COX), the key enzyme required for the conversion of arachidonic acid to prostaglandins was first identified over 20 years ago. Drugs, like aspirin, that inhibit cyclooxygenase activity have been available to the public for about 100 years.
Abramson, Steven B. +6 more
core +1 more source
Expression of Cyclooxygenase-1 and Cyclooxygenase-2 in normal and pathological human oral mucosa
Folia Histochemica et Cytobiologica, 2010 Cyclooxigenase (COX) is the rate-limiting enzyme for the conversion of arachidonic acid (AA) to prostaglandins(PGs). Two isoforms of COX have been identified: COX-1 is constitutively expressed in many cells and is involved in cellhomeostasis ...
Annamaria Mauro +7 more
doaj
Mediators of Inflammation, 1995 It has been demonstrated that lysolecithin (lysophosphatidyl choline, LPC) produces experimental cholecystitis in cats mediated by arachidonic acid metabolites. LPC is a cytolytic agent that has been postulated as a contributing factor in the development
M. K. Nag +4 more
doaj +1 more source
Detection of non-melanoma skin cancer by in vivo fluorescence imaging with fluorocoxib A. [PDF]
, 2015 Non-melanoma skin cancer (NMSC) is the most common form of cancer in the US and its incidence is increasing. The current standard of care is visual inspection by physicians and/or dermatologists, followed by skin biopsy and pathologic confirmation.
Ali-Khan, Irfan +8 more
core +2 more sources
Expression of cyclooxygenase‐1 and cyclooxygenase‐2 in bronchial epithelium and nonsmall cell lung carcinoma [PDF]
Cancer, 2002 AbstractBACKGROUNDCyclooxygenase (Cox) is the main target enzyme for the nonsteroidal antiinflammatory drugs that have been shown to suppress carcinogenesis in both experimental models and epidemiologic studies.METHODSTo evaluate its utility as an intermediate biomarker in bronchial chemoprevention trials, the authors examined Cox 1 and Cox 2 ...
Shyla K. Kalapurakal +5 more
openaire +3 more sources
Role of Cyclooxygenase Pathway and Risk Associated with Non-Steroidal Anti-inflammatory Drugs Therapy in Cardiovascular Diseases [PDF]
, 2018 Non-steroidal anti-inflammatory drugs (NSAIDs) inhibit the cyclooxygenase enzyme activity through differentmechanisms and prevent inflammation. But they all have different risks associated with them.
Ganju, Lilly, Garg, Iti, Kumar, Vinay
core +2 more sources
, 2010 Our conclusion that “poor clinical outcomes of aspirin-treated patients is due in part to incomplete cyclooxygenase-1 (COX-1) inhibition, but is also due in part to COX-1–independent platelet hyperreactivity” is based on the independent association of ...
A. Frelinger +7 more
semanticscholar +1 more source
Neurobiology of Disease, 2007 Epidemiological and experimental data implicate maternal–fetal infection and an associated increase in circulating cytokines in the etiology of cerebral palsy.
Géraldine Favrais +3 more
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