Results 141 to 150 of about 207,862 (335)

Alternative splicing of human prostaglandin G/H synthase mRNA and evidence of differential regulation of the resulting transcripts by transforming growth factor beta 1, interleukin 1 beta, and tumor necrosis factor alpha. [PDF]

, 1992
Prostaglandin G/H synthase (PGG/HS) is the rate-limiting enzyme in the conversion of arachidonic acid to prostaglandins and thromboxanes. We screened a human lung fibroblast cDNA library with an ovine PGG/HS cDNA and isolated a 2.3-kilobase clone (HCO-T9)
Diaz, Arturo, Jimenez, Sergio A., Reginato, Anthony M.   +2 more
core   +1 more source

Heterogeneity of Rheumatoid Arthritis‐Associated Interstitial Lung Disease by Longitudinal Forced Vital Capacity Trajectory and Associations with Disease Outcomes

Arthritis Care &Research, Accepted Article.
Objective We aimed to identify unique disease trajectories within rheumatoid arthritis‐associated interstitial lung disease (RA‐ILD) based on longitudinal forced vital capacity (FVC) values and their associated clinical outcomes. Methods We performed a cohort study of RA‐ILD within the Veterans Health Administration from 1999‐2021. RA‐ILD patients were
Bryant R. England, Yangyuna Yang, Punyasha Roul, Tate M. Johnson, Scott M. Matson, Grant W. Cannon, Brian C. Sauer, Jeffrey R. Curtis, Joshua F. Baker, Ted R. Mikuls   +9 more
wiley   +1 more source

1,2-Diarylimidazoles as Inhibitors of Cyclooxygenase-2: A Quantitative Structure-Activity Relationship Study [PDF]

, 1999
Prithvi Singh, Rajesh Kumar
openalex   +1 more source

Serum uric acid levels in older adults: Associations with clinical outcomes and implications for reference intervals in those aged 70 years and over

Arthritis Care &Research, Accepted Article.
Objectives Reports have linked both high and low serum uric acid (SUA) levels to adverse health outcomes. This study aimed to establish a reference interval for SUA in older adults and assessed its association with clinically relevant outcomes in relatively healthy, community‐dwelling individuals aged 70 and older.
Amanda J Rickard, Cammie Tran, Hans G Schneider, Flavia M Cicuttini, Anita E Wluka, Ego Seeman, Johannes T Neumann, Md Nazmul Karim, Zhen Zhou, Sultana Monira Hussain, David P Q Clark, Daniel Clayton‐Chubb, Andrew M Tonkin, Lawrence J Beilin, Robyn L Woods, John J McNeil   +15 more
wiley   +1 more source

Chronic Opioids in Gout: A Matched Cohort Study from the Veteran's Health Administration

Arthritis Care &Research, Accepted Article.
Objective Though used frequently to treat flare, risk of chronic opioid exposure in gout has not been well defined. In this study, we examined the hypothesis that people with gout are more likely than individuals without gout to be prescribed chronic opioids over time.
Lindsay N. Helget, Bryant R. England, Punyasha Roul, Harlan Sayles, Tuhina Neogi, James R. O'Dell, Joshua F. Baker, Ted R. Mikuls   +7 more
wiley   +1 more source

The inhibitory effect of bis(2-((E)-2-octenoylamino)ethyl) disulfide on the cyclooxygenase pathway.

, 1989
TSUTOMU MIMURA, Hiroshi Nakajima, Kazutake Tsujikawa, Naohiro Yasuda, Munetada Haruyama, Masaru Okabe, Masakazu Iwai, Kazumasa Yokoyama   +7 more
openalex   +2 more sources

Expression of Cyclooxygenase-1 and Cyclooxygenase-2 in Human Breast Cancer [PDF]

, 1998
Daniel Hwang, Deborah A. Scollard, James V. Byrne, E.L. Levine   +3 more
openalex   +1 more source

The Regulation of Trace Metal Elements in Cancer Ferroptosis

Advanced Biology, EarlyView.
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang, Yuanyuan Xue, Lei Chang, Xuena Zhu, Wenjun Liu, Tingbo Liang   +5 more
wiley   +1 more source

Demonstration of an inducible cyclooxygenase in human endothelial cells using antibodies raised against the carboxyl-terminal region of the cyclooxygenase-2.

, 1993
Aı̈da Habib, Christophe Créminon, Yveline Frobert, Jacques Grassi, P. Pradelles, Jacques Maclouf   +5 more
openalex   +1 more source

Expression of cyclooxygenase-2 in human hepatocellular carcinoma: Relevance to tumor dedifferentiation [PDF]

, 1999
Hironori Koga, Shotaro Sakisaka, Masahito Ohishi, Takumi Kawaguchi, Eitaro Taniguchi, Kurumi Sasatomi, Masaru Harada, Taku Kusaba, Masatoshi Tanaka, Rina Kimura, Yutaka Nakashima, Osamu Nakashima, Masamichi Kojiro, Toshihiko Kurohiji, Michio Sata   +14 more
openalex   +1 more source