Results 171 to 180 of about 108,418 (353)

An agent that releases basophil and mast cell histamine but blocks cyclooxygenase and lipoxygenase metabolism of arachidonic acid inhibits immunoglobulin E-mediated asthma in rhesus monkeys

, 1981
R PATTERSON, J PRUZANSKY, K HARRIS
openalex   +1 more source

Basic biology and clinical application of specific cyclooxygenase-2 inhibitors [PDF]

, 2000
Leslie J. Crofford, Peter E. Lipsky, Peter C. Brooks, Steven B. Abramson, Lee S. Simon, Leo B. A. Van De Putte   +5 more
openalex   +1 more source

H3K36me3‐Guided m6A Modification of Oncogenic L1CAM‐AS1 Drives Macrophage Polarization and Immunotherapy Resistance in Hepatocellular Carcinoma

Advanced Science, EarlyView.
L1CAM‐AS1 is identified as a novel H3K36me3‐guided, m6A‐modified long noncoding RNA (lncRNA) in hepatocellular carcinoma (HCC) cells. L1CAM‐AS1 stabilizes RAN protein, enhances M2 macrophages‐released CCL5‐induced nuclear import of RELA, activates the NF‐κB signaling, up‐regulates CCL2 expression and secretion from HCC cells, and enhances M2 ...
Teng Wang, Linyu Han, Yanfei Huo, Long Zhang, Yizhou Huang, Nasha Zhang, Ming Yang   +6 more
wiley   +1 more source

Effects of TZI-41127, inhibitor of 5-1ipoxygenase, and TZI-41078,dual inhibitor of 5-1ipoxygenase and cyclooxygenase, on active oxygen production

, 1988
Motohiro Kobayashi, Masakatsu Nozaki, Kaito Tsurumi, Takashi Mikami, Katsuhiko Miyasaka   +4 more
openalex   +1 more source

Cyclooxygenase-2–selective inhibitors impair glomerulogenesis and renal cortical development [PDF]

, 2000
Martin Kömhoff, Junling Wang, Huifang Cheng, Robert Langenbach, James A. McKanna, Raymond C. Harris, Matthew D. Breyer   +6 more
openalex   +1 more source

The Non‐Coding Regulatory Variant rs2863002 at chr11p11.2 Increases Neuroblastoma Risk by Affecting HSD17B12 Expression and Lipid Metabolism

Advanced Science, EarlyView.
The SNP rs2863002 at the 11p11.2 locus, identified through GWAS, is associated with an increased risk of neuroblastoma. The rs2863002‐C allele impairs the binding of the transcription factor GATA3, resulting in upregulation of the HSD17B12 gene.
Teresa Maiorino, Marianna Avitabile, Vincenzo Aievola, Annalaura Montella, Vito A. Lasorsa, Ferdinando Bonfiglio, Mariagrazia Cantalupo, Sueva Cantalupo, Gilda Estinto, Matilde Tirelli, Martina Morini, Martina Ardito, Alessandra Eva, Vincenza Cerbone, Lucia Mauriello, Marianna Caterino, Margherita Ruoppolo, John M. Maris, Sharon J. Diskin, Achille Iolascon, Mario Capasso   +20 more
wiley   +1 more source

Preoperative oral treatment with cyclooxygenase‐2 inhibitor for cystitis glandularis

IJU Case Reports
Introduction A previous report has shown that cyclooxygenase‐2 inhibitors can prevent the recurrence of cystitis glandularis postoperatively. Herein, we present a case of cystitis glandularis in which the tumor volume was markedly reduced by preoperative
Masato Yanagi, Norio Motoda, Akifumi Katsu, Hiroyoshi Kono, Ryoji Kimata, Tsutomu Hamasaki, Yukihiro Kondo   +6 more
doaj   +1 more source

INFLUENCE OF CYCLOOXYGENASE INHIBITORS ON PLASMA VOLUME AND PROTEIN DURING PROGRESSIVE EXERCISE

, 1984
James M. Pivarnik, Thomas Kayrouz, L. C. Senay   +2 more
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Mesenchymal Stromal Cell Secretome and Its Key Bioactive Metabolites Induce Long‐Term Neuroprotection After Traumatic Brain Injury in Mice

Advanced Science, EarlyView.
Pischiutta F and coworkers identify prostaglandins and kynurenine as key mediators of the mesenchymal stromal cells‐derived secretome's neuroprotective effects. A synthetic cocktail composed of these factors promotes long‐term functional recovery, reduces brain structural damage, and modulates neuroinflammation after traumatic brain injury, supporting ...
Francesca Pischiutta, Francesca Tribuzio, Marta Magatti, Giulia De Simone, Federico Moro, Giovanni Nattino, Fabiola Signorini, Luther Loose, Enrico Caruso, Costanza Bertani, Edoardo Mazzone, Rosaria Pascente, Edoardo Micotti, Antonietta Rosa Silini, Fabrizio Ortolano, Maria Chiara Trolese, Marco Bolis, Luca Guarrera, Martina Bruna Violatto, Paolo Bigini, Cristina Banfi, Roberta Pastorelli, Ornella Parolini, Laura Brunelli, Elisa R Zanier   +24 more
wiley   +1 more source

Piperazinealkanol Ester Derivatives of Indomethacin as Dual Inhibitors of 5-Lipoxygenase and Cyclooxygenase.

, 1994
Ichiro Yamawaki, Masataka Suzuki, Kazumi Ogawa   +2 more
openalex   +2 more sources