Results 181 to 190 of about 112,794 (342)

Indole Derivatives as Cyclooxygenase Inhibitors: Synthesis, Biological Evaluation and Docking Studies. [PDF]

Molecules, 2018
Bhat MA, Al-Omar MA, Raish M, Ansari MA, Abuelizz HA, Bakheit AH, Naglah AM.   +6 more
europepmc   +1 more source

Somatostatin inhibits colon cancer cell growth through cyclooxygenase‐2 downregulation

, 2008
Rocchina Colucci, Corrado Blandizzi, Narcisa Ghisu, Tullio Florio, Mario Del Tacca   +4 more
openalex   +2 more sources

Study of analgesic activity and effects of new dipharmacophores – nebracetam and cyclooxygenase-2 inhibitors derivatives on the cognitive abilities of rats [PDF]

, 2021
Vitaliy S. Slyusarenko, Ivan S. Koklin, Sergiy М. Kovalenko, В. П. Чуев, Alexey A. Shabalin, Vladimir V. Gureev, М. В. Корокин   +6 more
openalex   +1 more source

A Radioresistant‐Tumor‐Targeted Nanoparticle for X‐Ray‐Controlled Nitric Oxide Release to Potentiate Radiotherapy

Advanced Science, EarlyView.
The PBTN targets GRP78 and, upon X‐ray irradiation, generates ONOO− to induce immunogenic cell death, thereby activating CD8+ T cells and establishing a systemic antitumor immune response. ABSTRACT Nitric oxide (NO) treated radioresistant tumors by relieving hypoxia and blocking DNA repair, but its nonselective toxicity has precluded therapeutic use ...
Wanze Zhang, Xiaoyan Yin, Ting Wang, Hongfu Zhao, Zhipeng Zhao, Jinbao Wang, Cheng Tao, Xuanchu Ge, Yanze Li, Linlin Liu, Fuxin Xue   +10 more
wiley   +1 more source

Cyclooxygenase inhibitors potentiate receptor tyrosine kinase therapies in bladder cancer cells in vitro. [PDF]

Drug Des Devel Ther, 2018
Bourn J, Cekanova M.
europepmc   +1 more source

Roles of Opioid Receptor Subtype in the Spinal Antinociception of Selective Cyclooxygenase 2 Inhibitor

, 2010
Cheol Hun Choi, Woong Mo Kim, Hyung Gon Lee, Cheol Won Jeong, Chang Mo Kim, Seong Heon Lee, Myung Ha Yoon   +6 more
openalex   +2 more sources

Polymer Matrix‐Based 3D Culture Significantly Enhances the Differentiation and Immunomodulatory Functions of Human Adipose‐Derived Stem Cells

Advanced Science, EarlyView.
The 3D culture of human adipose‐derived stem cells (hADSCs) on a crosslinked cyclosiloxane‐based poly‐Z matrix platform enables the formation of spheroid structures enriched with extracellular matrix (ECM). These ECM‐enriched hADSC spheroids cultured on poly‐Z exhibit enhanced differentiation potential, immunomodulatory capacity, and in vivo ...
Changjin Seo, Dohyeon Kim, Junhyuk Song, Sun‐Young Kim, Youngju Son, Afia Tasnim Rahman, Sangyong Jon   +6 more
wiley   +1 more source

Differential effects of selective and non-selective cyclooxygenase inhibitors on fecal microbiota in adult horses. [PDF]

PLoS One, 2018
Whitfield-Cargile CM, Chamoun-Emanuelli AM, Cohen ND, Richardson LM, Ajami NJ, Dockery HJ.   +5 more
europepmc   +1 more source

Proton FLASH Exposure Preserves Gut Commensal Microbiomes and Spares Intestinal Stem Cells

Advanced Science, EarlyView.
This study highlights the role of Proton FLASH abdominal irradiation in sparing of intestinal stem cells and preservation of key gut microbial population resulting minimization of radiation toxicity in intestinal epithelium in mice. Our findings support the potential of Proton FLASH to improve the therapeutic ratio for abdominal radiation exposure ...
Rishi Man Chugh, Payel Bhanja, Emily Schueddig, Jufri Setianegara, Yuting Lin, Kenny Guida, Shujah Rehman, Stacey Krepel, Devin Koestler, Ronald C. Chen, Katherine L. Cook, Subhrajit Saha   +11 more
wiley   +1 more source

Network modeling of sporadic colorectal cancer reveals the importance of off-target effects of Cyclooxygenase inhibitors. [PDF]

NPJ Syst Biol Appl
Gebhart AR, Berns MMM, Snoeys J, Elassaiss-Schaap J, de Lange ECM.   +4 more
europepmc   +1 more source