Results 121 to 130 of about 827 (152)
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Role of cyclophilin a during oncogenesis
Archives of Pharmacal Research, 2010Cyclophilins (Cyps) are ubiquitously expressed proteins that are evolutionarily conserved. CypA is the most abundant among the Cyps and is expressed in the cytosol. With its chaperone and PPIase activities, CypA contributes to the maintenance of correct conformation of nascent or denatured proteins and also provides protection against environmental ...
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Cyclophilin A as a Target of Cisplatin Chemosensitizers
Current Cancer Drug Targets, 2014Platinum-based chemotherapeutics are the mainstay of treatment of a range of tumors achieving high response rates but limited in the course of disease by appearance of drug resistance. Tumor cells respond with reduced uptake and increased intracellular inactivation of the drugs, as well as increased DNA repair and general resistance to ...
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Cyclophilin A/CD147 Interaction: A Promising Target for Anticancer Therapy
International Journal of Molecular Sciences, 2022Hye Jin Jung, Jang Mi Han, Jung Hye Jin
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Delicate regulation of IL-1β-mediated inflammation by cyclophilin A
Cell Reports, 2022Wenjun Liu, Wei Liu, Lei Sun
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Cyclophilin D Modulates Mitochondrial Acetylome
Circulation Research, 2013Charles Steenbergen +2 more
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Cyclophilin A regulates HIV-1 infectivity, as demonstrated by gene targeting in human T cells
EMBO Journal, 2001Jeremy Luban, Douglas Braaten
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Cyclophilin A Is Secreted by a Vesicular Pathway in Vascular Smooth Muscle Cells
Circulation Research, 2006Bradford Berk, Tetsuya Matoba
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