Results 1 to 10 of about 154,726 (192)
BMJ, 1963 Cyclophosphamide, a recently-developed alkylating agent that may be administered orally, intramuscularly, and intravenously, was given to 135 patients with a wide variety of malignant diseases. Significant benefit was obtained in patients with lymphomas and leukemias as well as malignant melanoma, multiple myeloma, and carcinoma of the ovaries ...
G. Hamilton Fairley
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Post-transplant cyclophosphamide-induced cardiotoxicity: A comprehensive review [PDF]
Journal of Cardiovascular and Thoracic ResearchCyclophosphamide-induced cardiotoxicity, associated with its toxic metabolite acrolein, is a significant concern and unresolved issue, especially when cyclophosphamide is administrated in high doses.
Azin Alizadehasl +9 more
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Cyclophosphamide and the kidney [PDF]
Cancer, 1974 The effect of cyclophosphamide on renal function was studied in 17 normally hydrated patients with cancer. No nephrotoxic effects were observed. High-dose cyclophosphamide (⩾50 mg/kg body weight) did, however, impair water excretion as manifested by weight gain, hyponatremia, and inappropriately concentrated urine.
Ralph A. DeFronzo +4 more
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Food & Nutrition Research, 2021 Background: Lupus nephritis (LN) is one of the most severe organ that damages the systemic lupus erythematosus (SLE). Cyclophosphamide is one of the main drugs used in the treatment of LN.
Chi Zhang +3 more
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Cytochrome P450 Oxidoreductase Influences CYP2B6 Activity in Cyclophosphamide Bioactivation. [PDF]
PLoS ONE, 2015 Cyclophosphamide is commonly used as an important component in conditioning prior to hematopoietic stem cell transplantation, a curative treatment for several hematological diseases.
Ibrahim El-Serafi +4 more
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Pharmaceuticals, 2021 Infants and young children represent an important but much understudied childhood cancer patient population. The pharmacokinetics and pharmacogenetics of the widely used anticancer prodrug cyclophosphamide were investigated in children
Shelby Barnett +6 more
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A Study on the Alteration of Endoplasmic Reticulum Stress-related Proteins in Cyclophosphamide-induced Damage to Urothelium [PDF]
Pharmaceutical and Biomedical Research, 2023 Background: Cyclophosphamide is widely prescribed as an anti-cancer drug and used as an immunosuppressant. Hemorrhagic cystitis is one of the common complications of cyclophosphamide intake.
Hemalatha R +3 more
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The therapeutic effects of curcumin and capsaicin against cyclophosphamide side effects on the uterus in rats [PDF]
Acta Cirúrgica Brasileira, 2018 Purpose: To evaluate the impact of systemic cyclophosphamide treatment on the rat uterus and investigate the potential therapeutic effects of natural antioxidant preparations curcumin and capsaicin against cyclophosphamide side effects.
Ercan Yilmaz +5 more
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Nephrotoxicity Risk of Cyclophosphamide in Lupus Model
Journal of Tropical Pharmacy and Chemistry, 2021 Cyclophosphamide is one of the standard therapies for lupus, especially lupus nephritis based on its immunosuppressive effect. However, cyclophosphamide is also known as a nephrotoxic agent.
Niken Indriyanti
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