Results 21 to 30 of about 257,826 (338)

Paravasation with cyclophosphamide - Case report of tissue necrosis in a patient with primary breast cancer [PDF]

, 2007
Background: Paravasation is a rare but severe complication of treatment with cytotoxic agents. Some anticancer drugs are considered to be of high toxicity (vesicant), some are merely irritant, and some are regarded as nearly non-toxic to healthy tissue ...
Adami NP, Bertelli G, Boyle DM, Dorr RT, Goolsby TV, Jordan K, Reich B, Tsavaris NB   +7 more
core   +1 more source

Tumors That Acquire Resistance to Low-Dose Metronomic Cyclophosphamide Retain Sensitivity to Maximum Tolerated Dose Cyclophosphamide

Neoplasia: An International Journal for Oncology Research, 2011
Low-dose metronomic (LDM) chemotherapy is emerging as an alternative or supplemental dosing strategy to conventional maximum tolerated dose (MTD) chemotherapy. It is characterized primarily, but not exclusively, by antiangiogenic mechanisms of action and
Urban Emmenegger, Giulio Francia, Annabelle Chow, Yuval Shaked, Andrew Kouri, Shan Man, Robert S. Kerbel   +6 more
doaj   +1 more source

What is new in the management of rapidly progressive glomerulonephritis? [PDF]

, 2015
Rapidly progressive glomerulonephritis (RPGN) results from severe crescentic damage to glomeruli and leads to irreversible kidney failure if not diagnosed and managed in a timely fashion.
Greenhall, GHB, Salama, AD
core   +1 more source

Post-transplant cyclophosphamide-induced cardiotoxicity: A comprehensive review [PDF]

Journal of Cardiovascular and Thoracic Research
Cyclophosphamide-induced cardiotoxicity, associated with its toxic metabolite acrolein, is a significant concern and unresolved issue, especially when cyclophosphamide is administrated in high doses.
Azin Alizadehasl, Bita Shahrami, Reza Rahbarghazi, Azam Yalameh Aliabadi, Seyedeh Fatemeh Hosseini Jebelli, Yasamin Afsari Zonooz, Hoda Hakimian, Farzaneh Fathi, Sara Forati, Aysa Rezabakhsh   +9 more
doaj   +1 more source

N-acetylcysteine modulates cyclophosphamide-induced immunosuppression, liver injury, and oxidative stress in miniature pigs

Journal of Animal Science and Technology, 2020
Cyclophosphamide, a cytotoxic anticancer agent, induces immunosuppression and has several adverse effects. N-acetylcysteine alleviates oxidative stress, liver injury, and intestinal tissue damage. The present study
Kyung Soo Kang, Sangsu Shin, Sang In Lee
doaj   +1 more source

Cognitive impairment and elevated peripheral cytokines in breast cancer patients receiving chemotherapy

Arquivos de Neuro-Psiquiatria, 2022
Background Anthracyclines-based regimen (5-fluorouracil, doxorubicin, and cyclophosphamide (FAC); cyclophosphamide, epirubicin, and 5-fluorouracil [CEF]) and non-anthracycline based regimens (cyclophosphamide, methotrexate, and 5-fluorouracil [
Mohd Ashif Khan, Dinesh Bhurani, Ubedul Hoda, Nouroz Sehar, Nidhi Agarwal   +4 more
doaj   +1 more source

Rapamycin Prevents cyclophosphamide-induced Over-activation of Primordial Follicle pool through PI3K/Akt/mTOR Signaling Pathway in vivo

Journal of Ovarian Research, 2017
Background Primordial follicular depletion has thought to be a common adverse effect of chemotherapy especially for female of reproductive age. The study aimed to evaluate the protective effect of rapamycin on the primordial follicles and its potential ...
Linyan Zhou, Yanqiu Xie, Song Li, Yihua Liang, Qi Qiu, Haiyan Lin, Qingxue Zhang   +6 more
doaj   +1 more source

Hamster-to-rat heart and liver xenotransplantation with FK506 plus antiproliferative drugs [PDF]

, 1993
Heterotopic hamster hearts transplanted to unmodified LEW rats underwent humoral rejection in 3 days. Survival was prolonged to a median of 4 days with 2 mg/kg/day FK506.
Cramer, D, Demetris, AJ, Makowka, L, Murase, N, Starzl, TE, Tanabe, M, Valdivia, L   +6 more
core   +1 more source

The Effect of Cyclophosphamide Chemotherapy on Ovarian AntiMüllerian Hormone Levels in Breast Cancer Patients

Indonesian Journal of Obstetrics and Gynecology, 2018
Objective: To evaluate cyclophosphamide effects on Anti- Müllerian hormone (AMH) levels in breast cancer patients treated with cyclophosphamide chemotherapy. Methods: This cohort prospective study was conducted in Dr.
Elisabeth G.K. Liga, Nusratuddin Abdullah, Eddy Tiro, St. Maisuri T. Chalid   +3 more
doaj   +1 more source

Effects of Koumiss on Intestinal Immune Modulation in Immunosuppressed Rats

Frontiers in Nutrition, 2022
Koumiss is a traditional fermented dairy product with health and medicinal benefits. It is very popular in the Inner Mongolia Autonomous Region of China.
Qinyu Li, Chunjie Zhang, Chunjie Zhang, Tuya Xilin, Mingyue Ji, Xiangxi Meng, Yulian Zhao, Bateer Siqin, Na Zhang, Minhui Li, Minhui Li, Minhui Li, Minhui Li   +12 more
doaj   +1 more source