Cyclopia: A Rare Congenital Malformation
Journal of Nobel Medical College, 2018 Cyclopia is a rare and lethal congenital anomaly of the forebrain system, resulting from incomplete cleavage of prosencephalon into right and left hemispheres occurring between the 18th and the 28th day of gestation.
Sunil Kumar Yadav +2 more
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Shortened primary cilium length and dysregulated Sonic hedgehog signaling in Niemann-Pick C1 disease [PDF]
, 2017 The Niemann-Pick type C1 (NPC1) disease is a neurodegenerative lysosomal storage disorder due to mutations in the NPC1 gene, encoding a transmembrane protein related to the Sonic hedgehog receptor, Patched, and involved in intracellular trafficking of ...
Canterini, Sonia +7 more
core +1 more source
The Birth of the Eye Vesicle: When Fate Decision Equals Morphogenesis
Frontiers in Neuroscience, 2018 As the embryonic ectoderm is induced to form the neural plate, cells inside this epithelium acquire restricted identities that will dictate their behavior and progressive differentiation.
Florence A. Giger, Corinne Houart
doaj +1 more source
Horizontal Transfer of Symbiosis Genes within and Between Rhizobial Genera : Occurrence and Importance [PDF]
, 2018 Rhizobial symbiosis genes are often carried on symbiotic islands or plasmids that can be transferred (horizontal transfer) between different bacterial species. Symbiosis genes involved in horizontal transfer have different phylogenies with respect to the
Baraúna +16 more
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The Biochemical and Genetic Odyssey to the Function of a Nicastrin-Like Protein [PDF]
, 2004 gamma-Secretase is a high-molecular-weight protein complex required for the proteolytic processing of various transmembrane proteins including the Alzheimer's disease-associated amyloid precursor protein and the signaling receptor Notch. One of the gamma-
Haass, Christian, Haffner, Christof
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A novel six3 mutation segregates with holoprosencephaly in a large family [PDF]
, 2009 Holoprosencephaly is the most common structural malformation of the forebrain in humans and has a complex etiology including chromosomal aberrations, single gene mutations and environmental components.
Abecasis +40 more
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Saudi medical journal, 2004 True cyclopia is a rare anomaly in which the organogenetic development of the 2 separate eyes is suppressed. We report a fetus with an association of cyclopia with other anomalies. The possible mechanism of the histogenesis is discussed, together with a review of the relevant literature.
Yilmaz, F, Kilinc, N
+7 more sources
Evaluation of the phytoestrogenic activity of Cyclopia genistoides (honeybush) methanol extracts and relevant polyphenols [PDF]
, 2007 The original publication is available at http://pubs.acs.org/Unfermented C. genistoides methanol extracts of different harvestings and selected polyphenols were evaluated for phytoestrogenic activity by comparing binding to both ER subtypes ...
Joubert, Elizabeth +2 more
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Experimental and modeling studies on microwave-assisted extraction of mangiferin from Curcuma amada [PDF]
, 2013 Mangiferin, a bioactive compound having potent nutraceutical, strong antioxidant and pharmacological significance has been extracted using microwave-assisted extraction (MAE) technique from Curcuma amada, commonly known as mango ginger.
Chaudhuri, Surabhi +4 more
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Mangiferin has an additive effect on the apoptotic properties of hesperidin in Cyclopia sp. tea extracts. [PDF]
PLoS ONE, 2014 A variety of biological pro-health activities have been reported for mangiferin and hesperidin, two major phenolic compounds of Honeybush (Cyclopia sp.) tea extracts.
Rafal Bartoszewski +7 more
doaj +1 more source