Results 11 to 20 of about 5,138 (211)

Analysis of the Differentially Expressed Proteins and Metabolic Pathways of Honeybush (Cyclopia subternata) in Response to Water Deficit Stress [PDF]

Plants, 2023
Honeybush (Cyclopia spp.) is a rich source of antioxidant properties and phenolic compounds. Water availability plays a crucial role in plant metabolic processes, and it contributes to overall quality.
Mary-Jane S. Mahlare, Lizex Husselmann, Muinat N. Lewu, Cecilia Bester, Francis B. Lewu, Oluwafemi James Caleb   +5 more
doaj   +2 more sources

The Genus Cyclopia , Vent

Bothalia: African Biodiversity & Conservation, 1922
No abstract ...
Joan Hofmeyer, E. P. Phillips
doaj   +3 more sources

A Rare Case Report on Holoprosencephaly With Cyclopia: Jimma University Medical Center, Ethiopia. [PDF]

Case Rep Obstet Gynecol
Background Holoprosencephaly is a congenital brain malformation resulting from incomplete division of the forebrain (prosencephalon) into two hemispheres during early embryonic development, typically during the 4th–6th week of gestation. Cyclopia is a rare and fatal form of holoprosencephaly characterized by severe craniofacial abnormalities resulting ...
Debela DT, Disasa FA, Girma A, Seto SJ.
europepmc   +2 more sources

Ophthalmologic Findings in an Induced Model of Holoprosencephaly in Zebrafish. [PDF]

J Comp Neurol
We used a zebrafish (Danio rerio) model to variably induce bmp4 during embryonic development. We show ophthalmologic phenotypes of variable severity depending on the length and onset of bmp4 inductions. We find phenotypes like ocular hypotelorism, synophthalmia, cyclopia, and anophthalmia, which are described to be part of the HPE spectrum.
Bulk J, Kyrychenko V, Heermann S.
europepmc   +2 more sources

The Sensory and Physicochemical Properties of Honeybush Tea Depend on the Brewing Water: A Preliminary Study. [PDF]

J Food Sci
ABSTRACT This study investigated how different water types affected honeybush (Cyclopia species) tea quality. Water types, varying in physicochemical properties, were used to brew tea from three honeybush species: C. intermedia, C. subternata, and C. genistoides (n = 6/species).
van Schoor H, Moelich E, von Pressentin du Preez B, Human C, de Beer D, Joubert E.   +5 more
europepmc   +2 more sources

Interactions between the bone morphogenetic protein and the planar cell polarity pathways lead to distinctive ethanol-induced facial defects. [PDF]

Alcohol Clin Exp Res (Hoboken)
Gene–ethanol interactions lie at the heart of FASD. However, the relationship between ethanol‐sensitive genes and the timing and duration of exposure is not well‐understood. Using morphometric and multivariate analyses in zebrafish, vangl2 and gpc4 mutants are ethanol‐sensitive from 10 to 24 h postfertilization, not before or after, leading to facial ...
Gray R, Lloyd A, Lovely CB.
europepmc   +2 more sources

Sonographic diagnosis of fetal eye anomalies and their association with syndromal diseases: A retrospective multicenter analysis of 264 cases. [PDF]

Acta Obstet Gynecol Scand
Finding ocular abnormalities in fetal scans should lead to an exhaustive exploration of the fetus. Including evaluation of the fetal eye in standard first and second‐trimester ultrasound protocols should be assessed. Abstract Introduction This study aims to systematically describe eye malformations and correlate these with extraocular findings.
Jiménez Cruz J, Böckenhoff P, Tascón Padrón L, Emrich N, Kosian P, Strizek B, Berg C, Weber E, Gembruch U, Geipel A.   +9 more
europepmc   +2 more sources

Autophagy-induced cell death by aqueous and polyphenol-enriched extracts of honeybush (Cyclopia spp.) in liver and colon cancer cells. [PDF]

Food Sci Nutr
Aqueous extracts of honeybush have been found to decrease cell viability and hinder cell proliferation in HepG2 and HT‐29 cells. While they did not affect apoptosis, they induced autophagy in both cancer cell lines. Similarly, honeybush polyphenols, mangiferin, and hesperidin, when in pure form, also diminished cell viability and impeded cell ...
Samodien S, de Kock M, Joubert E, de Beer D, Kriel J, Gelderblom WCA, Lilly M.   +6 more
europepmc   +2 more sources

Microbial and functional diversity of Cyclopia intermedia rhizosphere microbiome revealed by analysis of shotgun metagenomics sequence data

Data in Brief, 2020
Cyclopia spp., commonly referred to as honeybush due to the honey scented flowers, are indigenous legumes mainly growing in the Cape Floristic Region of the Western Cape, South Africa. Dozens of species, including Cyclopia intermedia, C.
Ahmed Idris Hassen, Rian Pierneef, Z.H. Swanevelder, F.L. Bopape   +3 more
doaj   +1 more source

Cyclopia: A Rare Congenital Anomaly

Journal of Karnali Academy of Health Sciences, 2023
Cyclopia is the most extreme form of holoprosencephaly. It is characterized by the failure of the embryonic prosencephalon to properly divide the orbits of the eye into two cavities which results in babies with a single or partially divided eye in a ...
Uttara Gautam, Sandeep Shrestha, Rajan Phuyal   +2 more
doaj   +1 more source