Results 11 to 20 of about 2,872 (213)

Cyclopia

Saudi Medical Journal, 2003
True cyclopia is a rare anomaly in which the organogenetic development of the 2 separate eyes is suppressed. We report a fetus with an association of cyclopia with other anomalies. The possible mechanism of the histogenesis is discussed, together with a review of the relevant literature.
Fahri, Yilmaz, Nihal, Kilinc
openaire   +3 more sources

Cyclopia with proboscis: A rare congenital anomaly

Clinical Case Reports, 2021
Cyclopia with a proboscis, a rare congenital anomaly, and a severe form of holoprosencephaly occur as a result of incomplete separation of prosencephalon into two halves of hemispheres during organogenesis.
Asma Kunwar, Bibek Man Shrestha, Suraj Shrestha, Pooja Paudyal, Suniti Rawal   +4 more
doaj   +2 more sources

Comprehensive Phenolic Profiling of Cyclopia genistoides (L.) Vent. by LC-DAD-MS and -MS/MS Reveals Novel Xanthone and Benzophenone Constituents

Molecules, 2014
A high-performance liquid chromatographic (HPLC) method coupled with diode-array detection (DAD) was optimized for the qualitative analysis of aqueous extracts of Cyclopia genistoides.
Theresa Beelders, Dalene de Beer, Maria A. Stander, Elizabeth Joubert   +3 more
doaj   +3 more sources

A Rare Case Report on Holoprosencephaly With Cyclopia: Jimma University Medical Center, Ethiopia. [PDF]

Case Rep Obstet Gynecol
Background Holoprosencephaly is a congenital brain malformation resulting from incomplete division of the forebrain (prosencephalon) into two hemispheres during early embryonic development, typically during the 4th–6th week of gestation. Cyclopia is a rare and fatal form of holoprosencephaly characterized by severe craniofacial abnormalities resulting ...
Debela DT, Disasa FA, Girma A, Seto SJ.
europepmc   +2 more sources

Ophthalmologic Findings in an Induced Model of Holoprosencephaly in Zebrafish. [PDF]

J Comp Neurol
We used a zebrafish (Danio rerio) model to variably induce bmp4 during embryonic development. We show ophthalmologic phenotypes of variable severity depending on the length and onset of bmp4 inductions. We find phenotypes like ocular hypotelorism, synophthalmia, cyclopia, and anophthalmia, which are described to be part of the HPE spectrum.
Bulk J, Kyrychenko V, Heermann S.
europepmc   +2 more sources

The Sensory and Physicochemical Properties of Honeybush Tea Depend on the Brewing Water: A Preliminary Study. [PDF]

J Food Sci
ABSTRACT This study investigated how different water types affected honeybush (Cyclopia species) tea quality. Water types, varying in physicochemical properties, were used to brew tea from three honeybush species: C. intermedia, C. subternata, and C. genistoides (n = 6/species).
van Schoor H, Moelich E, von Pressentin du Preez B, Human C, de Beer D, Joubert E.   +5 more
europepmc   +2 more sources

First Case Report of Agnathia-Otocephaly Complex Reported in Niger. [PDF]

Clin Case Rep
ABSTRACT Agnathia–otocephaly complex (AOC) is an extremely rare congenital malformation resulting from a disorder of the first branchial arch. In the past, this condition was considered lethal. However, milder variants of the isolated type of AOC have been reported as non‐lethal.
Diaouga HS, Dogbe YZKO, Garba RM, Nayama M.   +3 more
europepmc   +2 more sources

Severe Holoprosencephaly With Arhinencephaly in A Liveborn Neonate: A Case Report. [PDF]

Clin Case Rep
Physical examination revealed a‐hypotelorism, b‐arhinia, and c‐cleft lip and palate. ABSTRACT Holoprosencephaly (HPE) is a rare congenital brain malformation resulting from incomplete separation of the cerebral hemispheres. It has an estimated prevalence of 1 in 10,000 live births.
Kebbeh SK, Nawfal HI.
europepmc   +2 more sources

Interactions between the bone morphogenetic protein and the planar cell polarity pathways lead to distinctive ethanol-induced facial defects. [PDF]

Alcohol Clin Exp Res (Hoboken)
Gene–ethanol interactions lie at the heart of FASD. However, the relationship between ethanol‐sensitive genes and the timing and duration of exposure is not well‐understood. Using morphometric and multivariate analyses in zebrafish, vangl2 and gpc4 mutants are ethanol‐sensitive from 10 to 24 h postfertilization, not before or after, leading to facial ...
Gray R, Lloyd A, Lovely CB.
europepmc   +2 more sources

Sonographic diagnosis of fetal eye anomalies and their association with syndromal diseases: A retrospective multicenter analysis of 264 cases. [PDF]

Acta Obstet Gynecol Scand
Finding ocular abnormalities in fetal scans should lead to an exhaustive exploration of the fetus. Including evaluation of the fetal eye in standard first and second‐trimester ultrasound protocols should be assessed. Abstract Introduction This study aims to systematically describe eye malformations and correlate these with extraocular findings.
Jiménez Cruz J, Böckenhoff P, Tascón Padrón L, Emrich N, Kosian P, Strizek B, Berg C, Weber E, Gembruch U, Geipel A.   +9 more
europepmc   +2 more sources