Results 91 to 100 of about 17,328 (234)
SYNTHESIS, LSD1 INHIBITORY ACTIVITY, AND LSD1 BINDING MODEL OF OPTICALLY PURE LYSINE-PCPA CONJUGATES
Compounds that inhibit the catalytic function of lysine-specific demethylase 1 (LSD1) are interesting as therapeutic agents. Recently, we identified three lysine-phenylcyclopropylamine conjugates, NCD18, NCD25, and NCD41, which are potent LSD1 ...
Yukihiro Itoh +4 more
doaj +1 more source
[2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]methanol
The title compound, C19H16FNO, crystallizes with two independent molecules in the asymmetric unit. In the two molecules, the dihedral angles between the benzene and quinoline rings are 72.6 (5) and 76.2 (5)°, between the ...
Hongshun Sun, Hong Xu, Yu-Long Li
doaj +1 more source
Sulfur‐Directed Construction of Vinyl Cyclopropanes from 1,3‐Dienes
Sulfur takes control. A pending thioether acts as a molecular compass, directing carbene addition to the 1,3‐diene scaffold with exceptional regio‑ and diastereocontrol to forge sulfur‐substituted vinyl cyclopropanes (S‐VCPs) — molecular architectures inaccessible via conventional cyclopropanation strategies.
Anna Keimer +6 more
wiley +1 more source
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openaire +2 more sources
(Dicyclopropylmethylene)cyclopropane underwent efficient Bronsted acid catalyzed hydrations and hydroaminations with H2O and basic amines, respectively, occurring with conservation of all three cyclopropane rings.Fonds der Chemischen Industrie; EPSRC ...
Dmitry Yufit +7 more
core +1 more source
Emerging Trends in Organic Photoreactions Utilizing Disulfides
Disulfides are versatile, nontoxic alternatives to metal photocatalysts. This review explores their role as photoactivated thiyl‐radical precursors and bifunctional catalysts (HAT/electron shuttling) in diverse transformations. Strategies for electronic tuning and development into recyclable heterogeneous materials are highlighted for sustainable ...
Sunil Kumar +3 more
wiley +1 more source
Background Cyclopropane fatty acids (CPA) have been found in certain gymnosperms, Malvales, Litchi and other Sapindales. The presence of their unique strained ring structures confers physical and chemical properties characteristic of unsaturated fatty ...
Rawat Richa, Yu Xiao-Hong, Shanklin John
doaj +1 more source
Cyclic Olefin Copolymers as Versatile Materials for Advanced Engineering Applications
Cyclic olefin copolymers (COCs) are presented as highly versatile materials combining tunable synthesis, excellent optical properties, and mechanical robustness. Their potential spans microfluidics, bioengineering, and advanced electronics, while emerging self‐healing and sustainable solutions highlight future opportunities.
Giulia Fredi +3 more
wiley +1 more source
A high-resolution study of the rotational Raman spectra of cyclopropane and cyclopropane-d6 has yielded the values 0.66962 ± 0.00020 cm−1 and 0.46079 ± 0.00015 cm−1 for their ground-state rotational constants.
W. Jeremy Jones, B. P. Stoicheff
core +1 more source

