Results 101 to 110 of about 21,746 (290)

Concise Synthesis of (+)-allo-Kainic Acid via MgI2-Mediated Tandem Aziridine Ring Opening-Formal [3+2] Cycloaddition [PDF]

, 2013
3-Methyl vinyl aziridine undergoes a mild MgI2-promoted S(N)2' ring opening and concomitant cyclization with fumarate Michael acceptors to give trisubstituted pyrrolidines. The process is efficient and highly diastereoselective. This methodology has been
Aggarwal, Varinder K., Arena, Giada, Chen, Chia-Chun, Leonori, Daniele   +3 more
core   +1 more source

Competitive Cationic Pathways and the Asymmetric Synthesis of 1,2-Disubstituted Cyclopropanes: Insight into the Cyclopropylcarbinyl Cation

, 2022
Bruce J. Melancon
openalex   +1 more source

Quantifying the Electrophilicity of 9(10H)‐Phenanthrenone‐ and 1‐Acenaphthenone‐Derived α, β‐Unsaturated Ketones

Journal of Physical Organic Chemistry, Volume 39, Issue 2, February 2026.
The electrophilicities (Mayr E) of the α, β‐unsaturated ketones A and B were determined by kinetic studies of their reactions with carbanions (reference nucleophiles) in DMSO at 20°C. The different reactivities of A and B were rationalized by DFT calculations.
Christoph Gross, Jan Brossette, Luc Schellmann, Peter Mayer, Hendrik Zipse, Armin R. Ofial   +5 more
wiley   +1 more source

Inactivation of the Burkholderia Toxin Malleicyprol by Enzymatic Cyclopropanol Ring Opening

Angewandte Chemie, Volume 138, Issue 2, 9 January 2026.
Burkholderia pseudomallei and Burkholderia mallei are dangerous pathogens that cause severe diseases with high mortality rates. Their virulence relies in part on malleicyprols, potent toxins containing a highly reactive cyclopropanol group. In this study, we identify BurK, a heme‐dependent oxidoreductase that neutralizes malleicyprols by enzymatically ...
Jonas Fiedler, Ingrid Richter, Katharina Dornblut, Alicia Scharf, Christian Hertweck   +4 more
wiley   +2 more sources

Oxetanes: Recent Advances in Synthesis, Reactivity and Medicinal Chemistry [PDF]

, 2016
The 4-membered oxetane ring has been increasingly exploited for its behaviors, i.e. influence on physicochemical properties as a stable motif in medicinal chemistry, and propensity to undergo ring opening reactions as a synthetic intermediate.
Bull, JA, Croft, RA, Davis, OA, Doran, R, Morgan, KF   +4 more
core   +1 more source

Thiophenderivate als vielseitige Vorstufen für die Synthese von (Hetero)aromaten und Naturstoffen

Angewandte Chemie, Volume 138, Issue 5, 28 January 2026.
Verborgen, aber leistungsstark: Thiophene und ihre gesättigten Analoga haben sich als vielseitige C4‐Bausteine erwiesen, die sich effektiv in der Naturstoffsynthese sowie beim Aufbau funktionalisierter (Hetero)aromaten einsetzen lassen. Dieser Minireview soll einen Überblick über Strategien zur Anwendung dieser schwefelhaltigen heterozyklischen ...
Anna Keimer, Franz‐Lucas Haut
wiley   +1 more source

Bifunctional Aziridines from Photochemically Generated FSO2NH2 for SuFEx Diversification of Alkenes

Angewandte Chemie, Volume 138, Issue 2, 9 January 2026.
Photochemically generated FSO2NH2 serves as a safe, practical nitrene precursor for Rh‐catalyzed aziridination of alkenes, granting access to previously inaccessible fluorosulfonyl aziridines. These bifunctional electrophiles merge aziridine ring strain with SuFEx reactivity to provide a modular platform toward aliphatic sulfamoyl fluoride derivatives ...
Avinash Choudhury, Varun Prabhakar, Zakary B. Newman, Quentin Michaudel   +3 more
wiley   +2 more sources

Manganese(III) Acetate-mediated Oxidative Cyclization of a-Methylstyrene and trans-Stilbene with b-Ketosulfones

Molecules, 2013
A convenient microwave irradiation protocol was utilized for the synthesis of b-ketosulfones 1–5 in good yields. These sulfones reacted with alkenes through a radical oxidative cyclization mediated by Mn(OAc)3.
Patrice Vanelle, Clémence Tabelé, Christophe Curti, Ahlem Bouhlel   +3 more
doaj   +1 more source

Diazo Compounds and Phenyliodonium Ylides in Inter- and Intramolecular Cyclopropanations Catalyzed by Dirhodium(II). Synthesis and Chiral Resolution by GC versus HPLC [PDF]

, 2018
Summary.: The dirhodium(II)-catalyzed intermolecular cyclopropanation of a set of olefins with either diazo free phenyliodonium ylides or diazo compounds afforded cyclopropanes derived from Meldrum's acid, dimethyl malonate, (silanoxyvinyl)diazoacetates,
Aboul-Enein, Hassan Y., Ghanem, Ashraf, Lacrampe, Fabienne, Schurig, Volker   +3 more
core  

Evaluating the thermal vinylcyclopropane rearrangement (VCPR) as a practical method for the synthesis of difluorinated cyclopentenes : experimental and computational studies of rearrangement stereospecificity [PDF]

, 2014
Vinyl cyclopropane rearrangement (VCPR) has been utilised to synthesise a difluorinated cyclopentene stereospecifically and under mild thermal conditions.
Adam, Anderl, Antony, Audouard, Bakalova, Baldwin, Baldwin, Baldwin, Barth, Becke, Benson, Bowry, Brahms, Bremer, Buttle, Csuk, Danheiser, Davidson, Dolbier, Dolbier, Dolbier, Doubleday, Ellis, Erbes, Eusterwiemann, Fedoryński, Goldschmidt, Grimme, Gritsch, Harrington, Houk, Hudlicky, Itoh, Jiao, Kobayashi, Kobayashi, Kyne, Lee, Lewis, Li, Loncharich, Mase, Maskill, Miles, Mitsch, Morikawa, Mulzer, Munemori, Nendel, Neureiter, Newcomb, Newcomb, ONeal, Overberger, Percy, Roth, Schlag, Seyferth, Seyferth, Shibuya, Smart, Tian, Tian, Vatèle, Vogel, Wang, Wang, Wellington, Willcott, Willcott, Yang, Yudin, Zeiger, Zhao, Zhao, Zhao, Zuo   +76 more
core   +1 more source