Results 151 to 160 of about 28,372 (298)
FeIII‐Mediated Synthesis of Azaspirodienones via Ipso‐Radical Cyclization of Ugi–4CR Adducts
European Journal of Organic Chemistry, Volume 29, Issue 39, 22 October 2026.An efficient two‐step protocol for the synthesis of azaspirodienones via Fe‐mediated ipso‐radical cyclization of Ugi adducts has been developed. This methodology provides rapid access to these privileged spirocyclic architectures under mild conditions, offering a practical and versatile approach to generating structurally complex molecules with ...
Silvia J. Becerra–Anaya +2 more
wiley +1 more source
Angewandte Chemie, Volume 138, Issue 42, 12 October 2026.The use of 1,1,3,3‐tetramethyldisiloxane (TMDSO) and potassium tert‐butoxide enables direct alkylation of weakly acidic carbon–hydrogen bonds with alkyl halides. Experimental and computational studies support the formation of a substrate‐associated hydride‐like base, providing a single‐step alternative to the classical deprotonation and electrophile ...
Piers St. Onge +4 more
wiley +2 more sources
Angewandte Chemie, Volume 138, Issue 42, 12 October 2026.Electrocatalytic polarity inversion of azlactones unlocks their coupling with electron‐rich reaction partners. Triarylamine‐mediated oxidation of the azlactone enolate generates an electrophilic radical intermediate that undergoes selective C4 functionalization with diverse SOMOphiles.
Paula Rodríguez +6 more
wiley +2 more sources
Highly efficient construction of angular polycycles
Nature CommunicationsAngular tricyclic and polycyclic skeletons feature typical cores in an intriguing type of natural products. We herein report the Lewis acids-catalyzed dearomative (3 + 2) cycloadditions of donor-acceptor cyclopropanes with benzene ring, by which ...
Yi Sun +3 more
doaj +1 more source
New reactions of 1-seleno-1-vinyl cyclopropanes
, 1981 1-lithio-1-vinyl-cyclopropanes and cyclobutanones are obtained in high yield from the readily available title ...
Halazy, S., Krief, A.
core
Angewandte Chemie, Volume 138, Issue 41, 5 October 2026.1,2‐Aryl migration involving in situ‐generated alkyl iodine(III) species proceeds through a previously unrecognized 1,2‐C/I(III) dyotropic rearrangement. Migratory aryl fluorination, acetoxylation, and alkoxylation of 2‐alkyl‐2‐aryl‐3‐iodopropanoates provide α‐heterofunctionalized products, accompanied by aryl migration from the α‐ to the β‐position ...
Chen‐Xu Liu +3 more
wiley +2 more sources
ChemSusChem, Volume 19, Issue 19, 14 October 2026.Simple calcium bis(amido) compounds are exceptionally potent hydrophosphination catalysts in DMSO solution. At ambient temperature or under irradiation, this catalyst successfully engages all manner of unsaturated substrates with primary and secondary phosphines with more than 100 examples of high conversion.
Moniruzzaman Moniruzzaman, Rory Waterman
wiley +1 more source
CHIMIA, 1996 Butyllithium requires activation in order to become capable of abstracting a proton from weakly acidic hydrocarbons like cyclopropanes, simple olefins, or arenes.
Florence Mongin +2 more
doaj
The Expanding Role of Diazirines in Synthetic Methodology
European Journal of Organic Chemistry, Volume 29, Issue 38, 13 October 2026.Beyond their established role in photoaffinity labeling, diazirines have emerged as versatile reagents in synthetic chemistry. This review highlights their dual reactivity as carbene and nitrogen‐transfer precursors, showcasing mechanistic insights and diverse applications in cyclopropanations, cycloadditions, skeletal editing, amination, heterocycle ...
Viktor Savic +3 more
wiley +1 more source