Results 71 to 80 of about 21,746 (290)

Methyl on the Bridge: 2‐Methyl Propellane as Precursor for 1,3‐Substituted 2‐Methylated Bicyclo[1.1.1]Pentanes

Chemistry – A European Journal, EarlyView.
The synthesis of 2‐methyl propellane and its conversion to various 1,2‐ and 1,2,3‐di‐ and trisubstituted bicyclopentanes is reported. Abstract Bicyclo[1.1.1]pentanes (BCPs) have emerged as isosteric replacements for mono‐ and para‐substituted benzene rings in medicinal and materials applications, involving substitution at the BCP bridgehead (1,3 ...
Sean R. Verschaeve, Mariana Gomes Manso, Tibo Van Eeckhoorn, Mark E. Light, Bruno Linclau   +4 more
wiley   +1 more source

Synthesis of a novel chemotype via sequential metal-catalyzed cycloisomerizations

Beilstein Journal of Organic Chemistry, 2012
Sequential cycloisomerizations of diynyl o-benzaldehyde substrates to access novel polycyclic cyclopropanes are reported. The reaction sequence involves initial Cu(I)-mediated cycloisomerization/nucleophilic addition to an isochromene followed by ...
Bo Leng, Stephanie Chichetti, Shun Su, Aaron B. Beeler, John A. Porco Jr.   +4 more
doaj   +1 more source

Zinc-Catalyzed Cyclopropenation of Alkynes via 2-Furylcarbenoids [PDF]

, 2014
Financial support from MINECO of Spain (CTQ2012- 20517-C02-01) is gratefully ...
González Rodríguez, María José, López García, Luis Ángel, Vicente Arroyo, Rubén   +2 more
core   +1 more source

SmI2/Sm‐Induced Reductive Silacyclization of Alkene/Diene Derivatives Using Dichlorosilanes or 1,2‐Dichlorodisilanes via Reductive Radical‐Polar Crossover

Chemistry – A European Journal, EarlyView.
A SmI2/Sm‐mediated silacyclization unlocks a concise route to 4–7‐membered silacycles from simple unsaturated substrates and dichlorosilanes/disilanes. The complementary functions of samarium reductants trigger a reductive radical–polar crossover, offering a versatile strategy for constructing multiple Si─C bonds efficiently.
Zhengwei Chen, Daigo Kondo, Tsutomu Mizota, Leo Onishi, Huiying Mu, Koji Miki, Akiya Ogawa, Kouichi Ohe   +7 more
wiley   +1 more source

Novel Sulfonium Reagents for the Modular Synthesis of Spiro[2.3]Hexanes and Heteroatom‐Containing Analogues: Synthesis, Application, and Evaluation as Bioisosteres

Angewandte Chemie, Volume 138, Issue 5, 28 January 2026.
Strained spirocyclic spiro[2.3]hexane and its heteroatom‐containing derivatives, including previously underrepresented 5‐oxa‐1‐azaspiro[2.3]hexanes and 1,5‐diazaspiro[2.3]hexanes, were synthesized via a modular approach of insertion of cyclobutane‐, oxetane‐, and azetidine‐containing sulfonium reagents into alkenes, carbonyls and imines.
Philipp Natho, Annarita Vicenti, Fabrizio Mastrolorito, Francesca De Franco, Lee Walsh‐Benn, Marco Colella, Ernesto Mesto, Emanuela Schingaro, Orazio Nicolotti, Antimo Gioiello, Renzo Luisi   +10 more
wiley   +2 more sources

P450-catalyzed asymmetric cyclopropanation of electron-deficient olefins under aerobic conditions [PDF]

, 2014
A variant of P450 from Bacillus megaterium five mutations away from wild type is a highly active catalyst for cyclopropanation of a variety of acrylamide and acrylate olefins with ethyl diazoacetate (EDA).
Arnold, Frances H., Kitto, Rebekah Z., Renata, Hans, Wang, Z. Jane   +3 more
core   +2 more sources

Charge State Influence on Stability and Isomerism in Dehydrogenated PAHs: Insights from Anthracene, Acridine, and Phenazine

ChemPhysChem, Volume 26, Issue 6, March 15, 2025.
The ionization of anthracene, acridine, and phenazine has been explored, along with the removal of one and two hydrogen atoms, to provide valuable information for astrochemists and to understand the behavior of the resulting structures and their electronic reorganization. Abstract In this study, we systematically explored the stability and isomerism of
Khaldia Zghida, Farouk Hamza Reguig, Manuel Alcamí, Al Mokhtar Lamsabhi   +3 more
wiley   +1 more source

Synthesis of novel β-aminocyclobutanecarboxylic acid derivatives by a solvent-free aza-Michael addition and subsequent ring closure [PDF]

, 2011
Novel beta-aminocyclobutanecarboxylic acid derivatives were prepared via a sequential solvent-free aza-Michael addition of benzophenone imine across 3-halopropylidenemalonates and base-induced ring closure.
Aitken, Appella, Brannock, Caine, Choudhary, Declerck, Fernandes, Fernandes, Fernandes, Frackenpohl, Fülöp, Fülöp, Gademann, Gauzy, Gauzy, Gellman, Gorrea, Hall, Imanzadeh, Izquierdo, Kiss, Krapcho, Kuhl, Lehnert, Liu, Mangelinckx, Mangelinckx, Mangelinckx, Mangelinckx, Martinek, Martín-Vilà, Mittendorf, Norbert De Kimpe, Oki, Palko, Rúa, Seebach, Seebach, Su, Sulmon, Sven Mangelinckx, Tamara Meiresonne, Torres, Trabocchi, White   +44 more
core   +1 more source

Characteristics of fungicide resistance in Asian soybean rust (Phakopsora pachyrhizi) in Paraguay for 2022–2023: insights from genetic mutations and molecular dynamics simulations

Pest Management Science, EarlyView.
Phakopsora pachyrhizi in Paraguay showed diverse resistance to DMI, SDHI, and QoI fungicides at both regional and intra‐field levels, likely driven by target mutation genes. Abstract BACKGROUND Phakopsora pachyrhizi, the causative agent of Asian soybean rust, poses a major threat to soybean production in South America. The rising incidence of fungicide
Ryusuke Hagihara, Ryo Okada, Takuya Hayashi, Hideaki Tateishi, Wilfrido Morel, Naoki Yamanaka   +5 more
wiley   +1 more source

Synthesis of organic liquid crystals containing selectively fluorinated cyclopropanes

Beilstein Journal of Organic Chemistry, 2020
This paper describes the synthesis of a series of organic liquid crystals (LCs) containing selectively fluorinated cyclopropanes at their termini. The syntheses used difluorocarbene additions to olefin precursors, an approach which proved straightforward
Zeguo Fang, Nawaf Al-Maharik, Peer Kirsch, Matthias Bremer, Alexandra M. Z. Slawin, David O’Hagan   +5 more
doaj   +1 more source