Results 101 to 110 of about 141,357 (291)

Buccal Mucosa as Substrate for Direct Immunofluorescence Should Be Included Early in the Diagnostic Work Up of Ocular Mucous Membrane Pemphigoid

JEADV Clinical Practice, EarlyView.
ABSTRACT Background In ocular mucous membrane pemphigoid (MMP) direct immunofluorescence (DIF) represents the gold standard for definitive diagnosis. However, up to 50% of ocular MMP cases do not meet the immunopathological criteria. In addition, the risk of exacerbating conjunctival cicatrization makes ocular biopsy technically difficult to obtain ...
Andrea Gabusi, Michelangelo La Placa, Davide Bartolomeo Gissi, Federica Filippi, Camilla Loi, Cosimo Misciali, Federico Bardazzi   +6 more
wiley   +1 more source

Assessing the Effect of Adalimumab in Granuloma Annulare: A Case Series and Literature Review

JEADV Clinical Practice, EarlyView.
ABSTRACT Granuloma annulare (GA) is a benign granulomatous skin disorder for which standardized treatment guidelines are lacking due to limited evidence. Adalimumab, a TNF‐α inhibitor, shows promise as a therapeutic option due to its potential to disrupt GA granulomas.
Adriana Caixinha Valorenzos, Line Kibsgaard, Trine Bertelsen   +2 more
wiley   +1 more source

A comparative analysis of drug-induced kidney injury adverse reactions between cyclosporine and tacrolimus based on the FAERS database

BMC Immunology
Background This study utilizes the FDA Adverse Event Reporting System (FAERS) database to compare the adverse reaction signals of cyclosporine and tacrolimus, two widely used immunosuppressants, in relation to drug-induced kidney injury. The findings aim
Min Xu, Shanggang Xu, Xueliang Yi
doaj   +1 more source

Curing Hepatitis C in Liver Transplant Recipients Is Associated with Changes in Immunosuppressant Use. [PDF]

, 2016
Background and aimsAll-oral interferon-free antivirals are highly effective in treating recurrent hepatitis C (HCV) infection in liver transplant (LT) recipients.
Bau, Sherona, Busuttil, Ronald W, Choi, Gina, Durazo, Francisco, El Kabany, Mohammed, Elashoff, David, Farid, Alexander, Grotts, Jonathan, Han, Steven, Jamal, Naadir, Jimenez, Melissa, Rheem, Justin, Saab, Sammy   +12 more
core   +2 more sources

Clinical Efficacy and Safety of Topical Roflumilast in Psoriasis: An Updated Systematic Review and Meta‐Analysis of Randomized Controlled Trials

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Traditional first‐line topical treatments for plaque psoriasis, particularly corticosteroids and vitamin D analogs, frequently have only limited efficacy for long‐term use, and present difficulties with safety and adherence. Objectives In this systematic review and meta‐analysis of randomized controlled trials (RCTs), we assessed ...
Aimal A. Khattak, Ahmed Javed, Ummi Aiman Rahman, Rumaisa Riaz, Zeeshan Imtiaz, Hassan A. Mirza, Farman U. Khan, Muhid Khattak, Fatima Javid, Abdul Moiz Khan, Adeline L. Roy, Bibek Shrestha   +11 more
wiley   +1 more source

CASE STUDY OF USING THE DOMESTIC ANALOGUE OF CYCLOSPORINE A

Педиатрическая фармакология, 2010
The article illustrates results of an important trial for the Russian pharmaceutical industry, an assessment of the efficacy and safety of domestic immunosuppressive medication Cyclosporine A. A comparative analysis was made of pharmacokinetics, hepato-,
V.A. Goryainov, M.M. Kaabak, N.N. Babenko, N.T. Vorob'eva, L.A. Shishlo, M.M. Morozova, T.Yu. Cheprasova   +6 more
doaj   +2 more sources

Efficacy of Lebrikizumab in Patients With Severe Atopic Dermatitis Who Would be Eligible for Treatment Based on the South Korean Reimbursement Criteria

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Lebrikizumab is approved to treat patients with moderate‐to‐severe atopic dermatitis (AD). Objectives This study evaluated the 16‐week efficacy outcomes of lebrikizumab in adults and adolescents with severe AD in ADvocate trials who would be eligible for treatment based on South Korean reimbursement‐like criteria. Methods This was a
Chong Hyun Won, Chun Wook Park, Jiyoung Ahn, Joo Yeon Ko, Sang Hyun Cho, Yang Won Lee, Joo Hee Lee, Khai Jing Ng, Min Young Hong, Jinglin Zhong, Martin Dossenbach, Sang Wook Son   +11 more
wiley   +1 more source

Early and late outcomes after heart transplantation in a low-volume transplant centre [PDF]

, 2012
Early (one year) and late (15 year) outcomes after heart transplantation in Malta were evaluated by means of a retrospective analysis of mortality and morbidity, derived from the transplant database.
Manche, Alexander
core  

Cutaneous Squamous Cell Carcinoma Amongst Solid Organ Transplant Recipients: A Systematic Review of Molecular Alterations

JEADV Clinical Practice, EarlyView.
ABSTRACT Background As solid organ transplantation becomes more prevalent, more patients are living on long‐term immunosuppression, greatly increasing the risk of cutaneous squamous cell carcinoma (cSCC). Although significant improvements have been achieved in the treatment of cSCC, further studies are needed to identify the specific protein expression
William Murray, Robin Caird, Michael O'Connor, Ciara Drumm, Emma O'Hora, Franklin Crossen, Aoife Lally, Aurelie Fabre, Roisin Dolan   +8 more
wiley   +1 more source

The Effect of Cyclosporine and Tacrolimus Systemic Therapy on Gingival Overgrowth in Renal Transplant Patients Aged Between 18-70 Years in Erbil City-Iraq

Erbil Dental Journal
Background: Gingival overgrowth has been linked to systemic therapy with Cyclosporine and Tacrolimus in Renal transplanted cases. Aim: The prevalence and characteristics of gingival overgrowth and periodontal treatment will be examined in patients ...
Aveen A. Jalal
doaj   +1 more source