Results 11 to 20 of about 95,860 (291)
Cyclosporine related adverse events in aplastic anemia patients treated with immunosuppressive therapy [PDF]
Annals of HematologyBackground Few studies have focused on cyclosporine-related adverse events (AEs) in aplastic anemia (AA) patients undergoing immunosuppressive therapy and receive cyclosporine maintenance.
Lingxiao Xing +8 more
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Clinical efficacy of 0.05% cyclosporine nano-emulsion in the treatment of dry eye syndrome associated with meibomian gland dysfunction [PDF]
International Journal of Ophthalmology, 2022 AIM: To evaluate the clinical efficacy of topical 0.05% cyclosporine nano-emulsion in the treatment of dry eye syndrome (DES) with meibomian gland dysfunction (MGD).
Yeon Ji Jo, Ji Eun Lee, Jong Soo Lee
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Cyclosporine Nephrotoxicity [PDF]
Toxicologic Pathology, 1986 Cyclosporine (CSA) is a new immunosuppressant which has selectivity for the immune system and is without systemic side effects at therapeutic doses. In contrast to the cytotoxic class of immunosuppressants, no myelotoxic, teratogenic, mutagenic, or carcinogenic effects were observed.
B, Ryffel, M J, Mihatsch
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Crosstalk between Shh and TGF-β signaling in cyclosporine-enhanced cell proliferation in human gingival fibroblasts. [PDF]
PLoS ONE, 2013 BACKGROUND: Immunosuppressant cyclosporine-A induces gingival hyperplasia, which is characterized by increased fibroblast proliferation and overproduction of extracellular matrix components and regulated by transforming growth factor-beta (TGF-β).
Yi Chung, Earl Fu
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Cyclosporine Affects the Main Virulence Factors of Cryptococcus neoformans In Vitro
Journal of Fungi, 2023 This study aimed to investigate the effects of cyclosporine on the morphology, cell wall structure, and secretion characteristics of Cryptococcus neoformans.
Iara Bastos de Andrade +9 more
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Problems in pharmaceutical compounding of eye-drops with cyclosporine A [PDF]
Farmacja Polska, 2019 Cyclosporine A is very effective in treatment of many ophthalmic pathologies like immunological and inflammatory diseases of the cornea, conjunctive or uvea. It is also used to prevent corneal graft rejection and to treat dry eye syndrome.
Eliza Katarzyna Wolska +2 more
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Involvement of oxidative species in cyclosporine-mediated cholestasis
Frontiers in Pharmacology, 2022 Cyclosporine is an established medication for the prevention of transplant rejection. However, adverse consequences such as nephrotoxicity, hepatotoxicity, and cholestasis have been associated with prolonged usage. In cyclosporine-induced obstructive and
Bernard Nsengimana +4 more
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Clinics in Dermatology, 1989 Cyclosporine A (CsA) is a neutral lipophilic compound that was first isolated in the 1970s from the fungal species Tolypocladium inflatum gams. CsA is a cyclic polypeptide that consists of 11 amino acids and that has a molecular weight of 1202 daltons.1 It was found to have potent immunosuppressive properties and was initially used in the late 1970s to
Gupta, Aditya K. +7 more
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Breastfeeding by a mother taking cyclosporine for nephrotic syndrome
International Breastfeeding Journal, 2022 Background Cyclosporine is widely used for immunosuppressive treatment of various systematic and local autoimmune diseases. Breastfeeding is conventionally contraindicated when treating with cyclosporine due to its excretion into breast milk, which may ...
Ruizhe Li +3 more
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Renal Glycosuria without Hyperglycemia in Cyclosporine-Treated Rats
Kidney Research and Clinical Practice, 2012 The pathogenesis of post-transplant diabetes mellitus is thought to be partly related to the direct toxic effect of cyclosporine on pancreatic β-cells and the resultant decrease in insulin synthesis and secretion.
Chang Hwa Lee +3 more
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