Results 21 to 30 of about 204,688 (384)
Angiotensin type-2 (AT-2)-receptor activation reduces renal fibrosis in cyclosporine nephropathy: evidence for blood-pressure independent effect [PDF]
, 2016 Compound 21 (C21), selective agonist of AT2 receptors, shows antinflammatory effects in hypertension and nephroprotection in diabetes. The aim of this study was to evaluate the effects of C21 in cyclosporine nephropathy, which is characterized mainly by ...
Carletti, R +5 more
core +1 more source
Cyclosporine augments hepatic regenerative response in rats [PDF]
, 1990 A number of mechanisms participate in the hepatic injury that occurs during and following liver transplantation. A normal allograft regenerative response is probably essential for a successful transplant outcome. In this study, the effect of cyclosporine,
Dindzans, V +6 more
core +1 more source
Is Cyclosporine Ototoxic? [PDF]
Frontiers in Neurology, 2020 Cyclosporine was discovered in 1970, it was isolated from the fungus Tolypocladium inflatum in Switzerland (1). Soon after, an immunosuppressive property was suggested, and by 1978, it was used for the first time in human kidney transplantation to treat organ rejection post-transplant (2).
openaire +5 more sources
Renal Glycosuria without Hyperglycemia in Cyclosporine-Treated Rats
Kidney Research and Clinical Practice, 2012 The pathogenesis of post-transplant diabetes mellitus is thought to be partly related to the direct toxic effect of cyclosporine on pancreatic β-cells and the resultant decrease in insulin synthesis and secretion.
Chang Hwa Lee +3 more
doaj +1 more source
Canine liver transplantation under nva cyclosporine versus cyclosporine [PDF]
, 1986 The immunosuppressive qualities and other features of a new cyclosporine (CsA) analogue, Nva 2-cyclosporine (Nva 2-CsA) were examined using canine orthotopic liver allografts.
DeWolf, A +6 more
core +1 more source
The use of FK-506 for small intestine llotransplantation: Inhibition of acute rejection and prevention of fatal graft-versus-host disease [PDF]
, 1990 Small intestine allotransplantation in humans is not yet feasible due to the failure of the current methods of immunosuppression. FK-506, a powerful new immunosuppressive agent that is synergistic with cyclosporine, allows long-term survival of ...
Banner, B +7 more
core +1 more source
Oral administration of ginseng ameliorates cyclosporine-induced pancreatic injury in an experimental mouse model. [PDF]
PLoS ONE, 2013 BACKGROUND: This study was performed to investigate whether ginseng has a protective effect in an experimental mouse model of cyclosporine-induced pancreatic injury.
Sun Woo Lim +8 more
doaj +1 more source
Hepatology, EarlyView., 2022 In this study of the gut mucosal microbiota in primary sclerosing cholangitis (PSC), we found consistent microbiota features associated with PSC and recurrent PSC, PSC with inflammatory bowel disease and a persistent gut dysbiosis after liver transplantation Abstract Background and Aims Several characteristic features of the fecal microbiota have been ...
Mikal Jacob Hole +12 more
wiley +1 more source
Vasospasm is a significant factor in cyclosporine-induced neurotoxicity: Case report
BMC Neurology, 2010 Background The aetiology of central nervous system lesions observed in cerebral cyclosporine neurotoxicity remains controversial. Case presentation We report a 48-year-old woman with a non-severe aplastic anaemia who presented with stroke-like episodes ...
Span Lambert FR +4 more
doaj +1 more source
Biochemistry and Biophysics Reports, 2020 Background and aims: A relationship between treatment outcomes and intestinal microbiota in patients with inflammatory bowel diseases has been demonstrated. Cyclosporine treatment leads to rapid improvement in severe ulcerative colitis.
Shinji Ota +14 more
doaj +1 more source