Results 51 to 60 of about 141,357 (291)

The Effect of Systemic Methotrexate and Cyclosporine Combination Therapy inPsoriasis Vulgaris Patients in Bandung, Indonesia

Berkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology), 2021
Background: Methotrexate (MTX) and cyclosporine have been used as effective systemic mono-therapy for psoriasis. Several factors are considered to switch monotherapy to combination therapy because monotherapy is no longer effective and has higher side ...
Oki Suwarsa, Fatima Aulia Khairani, Syawalika Ulya Isneny, Erda Avriyanti, Hartati Purbo Dharmadji, Miranti Pangastuti, Endang Sutedja, Hendra Gunawan   +7 more
doaj   +1 more source

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

Advanced NanoBiomed Research, EarlyView.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari, Yunhui Min, Eun‐Ju Ko, Doyoung Kwon, Rehan Khan, Young‐Ok Son   +5 more
wiley   +1 more source

Cyclosporine-induced alopecia:a case report, FDA adverse event reporting system analysis and literature assessment

Frontiers in Pharmacology
Cyclosporine is a potent immunosuppressive drug for various immune-mediated diseases in children. Cyclosporine’s expected therapeutic effect also carries a wide range of side effects.
Ying Wang, Ying Wang, Youhong Wang, Youhong Wang, Ping Xu, Ping Xu   +5 more
doaj   +1 more source

Cyclosporine nephrotoxicity

Cleveland Clinic Journal of Medicine, 1989
Cyclosporine is a potent and useful immunosuppressive agent used primarily in conjunction with solid organ transplantation. The most serious adverse reaction that limits its use is nephrotoxicity due to effects on the renal vasculature, glomeruli, and tubular function. These effects result in a variety of clinical syndromes.
openaire   +2 more sources

Serious Infections in Offspring Exposed to Tumor Necrosis Factor Inhibitors During Pregnancy: Comparison of Timing During Pregnancy and Placental Transfer Ability

Arthritis &Rheumatology, EarlyView.
Objective We evaluated serious infection risk in offspring exposed to tumor necrosis factor inhibitors (TNFi) in utero, separated by TNFi timing and placental transfer ability. Methods Using MarketScan (2011–2021), we identified offspring born to mothers with chronic inflammatory diseases.
Leah K. Flatman, Sasha Bernatsky, Yvan St‐Pierre, Marie‐Eve Beauchamp, Isabelle Malhamé, Anick Bérard, Évelyne Vinet   +6 more
wiley   +1 more source

Interleukin‐18 Levels Are Associated With Disease Course in Patients With Still Disease Treated With Interleukin‐1 Inhibitors

Arthritis &Rheumatology, EarlyView.
Objective To evaluate the prognostic utility of circulating interleukin‐18 (IL‐18) levels in predicting disease activity, macrophage activation syndrome (MAS), and disease course in patients with Still disease (SD) receiving first‐line IL‐1 inhibitors (IL‐1i).
Matteo Trevisan, Manuela Pardeo, Ivan Caiello, Claudia Bracaglia, Arianna De Matteis, Valentina Matteo, Elena Loricchio, Fabrizio De Benedetti, Giusi Prencipe   +8 more
wiley   +1 more source

Radioprotective Effect of Selenium and Gamma Rays on Cyclosporine-Immunosuppressed Wistar Rats

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2017
Introduction: Cyclosporine is known as an immunosuppressive drug. Selenium has antioxidant characteristics. This study investigated the synergistic effects of radiation therapy emitted from Gamma rays with the protective effect of selenium after ...
Kourosh Bamdad, Zainab Safar, Mehrosadat Alavi   +2 more
doaj  

Mechanisms of hypertension during and after orthotopic liver transplantation in children [PDF]

, 1989
The aim of this study was to assess the hormonal alterations that may mediate the systemic hypertension that develops in patients during the perioperative period of orthotopic liver transplantation.
Akerstedt, Andrews, Ann Thompson, Arroyo, Bantle, Bantle, Baxter, Baylis, Bellet, Bernardi, Better, Bland, Bomzon, Bonjour, Borland, Busuttil, Cappuccio, Carlos Esquivel, Chrymko, Clement de Clety, Curtis, D. Ryan Cook, Demetrius Ellis, Epstein, Eskay, Filep, Floras, Gaillard, Gardner, Gartner, Gentile, Gerr, Glantz, Graystone, Henriksen, Hiatt, Januszewicz, Kimura, Kohno, Lau, Ledsome, Leslie, Loughran, Lustig, Mason, Minuk, Moss, Murrey, Nakai, Nicholls, Oaks, Ogawa, Palestine, Papadakis, Powell-Jackson, Ring-Larsen, Ring-Larsen, Rosanto, Salazar, Schacter, Seino, Shapiro, Skorecki, Starzl, Stephen Lawless, Task Force on Blood Pressure Control in Children, Thomas Starzl, Thompson, Vacanti, Voorhees, Weidle, Weidmann, Williams   +72 more
core   +1 more source

Efficacy and Safety of Subcutaneous Anifrolumab in Systemic Lupus Erythematosus: A Randomized, Phase 3 Study

Arthritis &Rheumatology, EarlyView.
Objective The multinational, phase 3, double‐blind, placebo‐controlled TULIP‐SC trial evaluated the efficacy and safety of subcutaneous anifrolumab in adults who have moderate to severe systemic lupus erythematosus (SLE) activity, despite receiving standard therapy. Methods Adults with SLE received subcutaneous anifrolumab 120 mg or placebo once weekly
Susan Manzi, Ian N. Bruce, Eric F. Morand, Richard Furie, Yoshiya Tanaka, Kenneth C. Kalunian, Anca Askanase, Patricia Puzio, Emon Khan, Jenny Wissmar, Michael Song, Catharina Lindholm, for the TULIP‐SC investigators   +12 more
wiley   +1 more source

Impact of Early Antimalarial Adherence on Future Acute Care Utilization and Cost Among Patients With Rheumatoid Arthritis and Systemic Lupus Erythematosus: A Population‐Based Study

Arthritis &Rheumatology, EarlyView.
Objective To assess the association between early antimalarial adherence and future acute care utilization and cost in a population‐based cohort of incident rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). Methods All patients with incident RA/SLE and new antimalarial use in British Columbia, Canada, between January 1997 and March 2022
Md Rashedul Hoque, Diane Lacaille, J. Antonio Aviña‐Zubieta, Mary A. De Vera, Yi Qian, Lawrence McCandless, John M. Esdaile, Hui Xie   +7 more
wiley   +1 more source