Results 61 to 70 of about 92,418 (213)

Cyclosporine A-nanoparticles enhance the therapeutic benefit of adipose tissue- derived stem cell transplantation in a swine myocardial infarction model

, 2013
Qiaoxiang Yin,1 Zhiyong Pei,2 Heng Wang,3 Yusheng Zhao4 1Department of Geriatric Cardiology, Chinese General Hospital of the Air Force, 2Department of Geriatric Cardiology, Beijing Military General Hospital, 3Department of Neurology, Chinese General ...
Yin QX, Pei ZY, Wang H, Zhao YS
core  

Cyclosporine-A induced cytotoxicity within HepG2 cells by inhibiting PXR mediated CYP3A4/CYP3A5/MRP2 pathway

Cyclosporine-A (CsA) is currently used to treat immune rejection after organ transplantation as a commonly used immunosuppressant. Liver injury is one of the most common adverse effects of CsA, whose precise mechanism has not been fully elucidated ...
Fan Zhou (196667), Huawen Xin (12301343), Weiliang Li (2606203), Shenglan Shang (12208562), Ling Tong (632992), Yan Zhao (58882), Airong Yu (65167), Mengchen Yu (17727573)   +7 more
core   +1 more source

The Pharmacokinetic Profile of Freeze-dried Cyclosporine A-Eudragit S100 Nanoparticle Formulation in Dogs

Nano Biomedicine and Engineering, 2011
The pharmacokinetic profile of freeze-dried cyclosporine A-Eudragit S100 nanoparticles (CyA-S100-NP)was studied with a random two-way crossover study in dogs.
Yang Liu, Zhigang Fang, Yagen Chen, Jiankang Zhang, Xuenong Zhang, Qiang Hong   +5 more
doaj   +1 more source

Cyclosporine nephrotoxicity

Cleveland Clinic Journal of Medicine, 1989
Cyclosporine is a potent and useful immunosuppressive agent used primarily in conjunction with solid organ transplantation. The most serious adverse reaction that limits its use is nephrotoxicity due to effects on the renal vasculature, glomeruli, and tubular function. These effects result in a variety of clinical syndromes.
openaire   +2 more sources

Effectiveness of a combination of cyclosporine A, suplatast tosilate and prednisolone on periodic oscillating hypereosinophilia

, 2011
Shinsaku Imashuku1, Ikuyo Ueda2, Tohru Inaba3 1Divisions of Pediatrics and Hematology, Takasago-seibu Hospital, Takasago, Japan; 2Department of Pediatrics, Kyoto Prefectural University of Medicine, Kyoto, Japan; 3Department of Infection Control and ...
Ueda I, Imashuku S, Inaba T
core  

Evaluation of the Efficacy of Topical Tacrolimus and Intraperitoneal Cyclosporine as a Treatment Method for Acute Rejection In vivo Model of Skin Allotransplantation

Turkish Journal of Plastic Surgery
Aims: Skin allotransplantation often results in graft rejection, necessitating the use of immunosuppressants. Tacrolimus (Tac) and cyclosporine A (CsA) are two commonly used immunosuppressants in this context.
Dilgam Mammadov, Kamuran Zeynep Sevim Aytuğ, Nedim Polat   +2 more
doaj   +1 more source

Antioxidant supplementation enhances erythrocyte antioxidant status and attenuates cyclosporine-induced vascular dysfunction

, 2006
The aim of this study was to determine the effects of dietary antioxidant supplementation with a-tocopherol and a-lipoic acid on cyclosporine induced alterations to erythrocyte and plasma redox balance, and cyclosporine-induced endothelial and smooth ...
Lexis, Louise., Lexis, L. A., Coombes, J. S., Andrew Fenning (9795698), Fassett, Robert., J.S. Coombes, Fenning, A., Fenning, Andrew., Coombes, Jeff., L Brown (9865289), L. Brown, Fassett, R. G., L.A. Lexis, L Lexis (9890348), A. Fenning, Brown, L., Brown, Lindsay., R.G. Fassett, R Fassett (9890351), J Coombes (9859394)   +19 more
core   +1 more source

Neuroprotective effects of cyclosporine A and GluR2 AMPA receptors against excitotoxicity in FVB/N and C57BL/6 mice

, 2015
Glutamate (Glu) is an important excitatory neurotransmitter in the brain. It\ud binds to ionotropic Glu receptors located in the postsynaptic membrane and allows\ud calcium into the cell. Abnormally high levels of Glu can induce excitotoxicity (seizure),\
Chin-Curtis, Alena
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Neoral: A Microemulsion Cyclosporine

, 1996
Cyclosporine (Sandimmune), introduced in the 1980s, improved patient and graft survival rates primarily by decreasing the frequency and severity of early, acute rejection.
David I Min
core   +1 more source

Prolonged cyclosporine treatment of severe or recalcitrant psoriasis: descriptive study in a series of 20 patients

, 2012
Background: Although long-term cyclosporine administration may induce toxic effects, it may be the only option for the treatment of severe psoriasis.
GIARI, Silvia, Bertoldi A. M., VIRGILI, Anna, BORGHI, Alessandro, MANTOVANI, Lucia, CORAZZA, Monica   +5 more
core   +1 more source