Results 131 to 140 of about 1,270 (196)
Drug repurposing screens reveal FDA approved drugs active against SARS-Cov-2
, 2020 Dittmar M +9 more
europepmc +1 more source
Group I pharmaceuticals of IARC and associated cancer risks: systematic review and meta-analysis. [PDF]
Sci RepLim W +8 more
europepmc +1 more source
Pathogenicity of <i>Tolypocladium</i> spp. Against <i>Plutella xylostella</i>: Effects on Immune Enzyme Activities and Gene Expression Profile. [PDF]
InsectsCai N +6 more
europepmc +1 more source
Folia Microbiologica, 1995 This review presents the progress and some aspects achieved during recent years with cyclosporin sources, chemistry, biological activities, side effects, biosynthesis and metabolism. Although incomplete the results indicate future research trends and some white spots to be studied in the near future to afford unique insights into cell biology and to ...
Z. Řeháček
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Features of spatial structures of cyclosporins D, E and G revealed by NMR and MD simulations
Journal of Molecular Liquids, 2021 Cyclosporins D, E and G were characterised by NMR spectroscopy, and backbone flexibility was studied by molecular dynamics simulation. Structures of the molecules were characterised by nuclear Overhauser effect spectroscopy, which revealed that the ...
I A Khodov
exaly +1 more source
Cyclosporins: immunosuppressive drugs with anti-HIV-1 activity
Trends in Molecular Medicine, 1995 Cyclosporin A was introduced into clinical use in the late 1970s to reduce graft rejection after organ transplantation. This drug, a cyclic undecapeptide metabolite of the fungus Tolypocladium inflatum, interferes with lymphokine biosynthesis, hence its ...
Markus Thali
exaly +2 more sources
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Southern Medical Journal, 1986
Cyclosporine is a fungal metabolite increasingly used as an immunosuppressive agent in organ transplantation. It provides immunosuppression primarily through reversible inhibition of T-lymphocytes, without myelotoxicity. Cyclosporine appears to inhibit primary activation of helper cells and to decrease the production of lymphokines by these cells ...
S E, Thomas, D S, Gordon
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Cyclosporine is a fungal metabolite increasingly used as an immunosuppressive agent in organ transplantation. It provides immunosuppression primarily through reversible inhibition of T-lymphocytes, without myelotoxicity. Cyclosporine appears to inhibit primary activation of helper cells and to decrease the production of lymphokines by these cells ...
S E, Thomas, D S, Gordon
openaire +2 more sources
Journal of the American Academy of Dermatology, 1986
Cyclosporin A is a new immunosuppressive agent that selectively affects T helper cells without suppressing the bone marrow. Cyclosporin A has been used primarily to prevent rejection in organ transplantation and acute graft-versus-host disease. Studies suggest that it may be of benefit in psoriasis, pemphigus vulgaris, bullous pemphigoid, Behçet's ...
E H, Page, D M, Wexler, L C, Guenther
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Cyclosporin A is a new immunosuppressive agent that selectively affects T helper cells without suppressing the bone marrow. Cyclosporin A has been used primarily to prevent rejection in organ transplantation and acute graft-versus-host disease. Studies suggest that it may be of benefit in psoriasis, pemphigus vulgaris, bullous pemphigoid, Behçet's ...
E H, Page, D M, Wexler, L C, Guenther
openaire +2 more sources
Drug Intelligence & Clinical Pharmacy, 1985
Cyclosporine is an immunosuppressant used to prevent the rejection of transplanted kidneys, hearts, and livers. Cyclosporine suppresses T-lymphocyte function without causing myelosuppression, and its pharmacokinetics are highly variable. Compared with conventional immunosuppressive drug therapy, both patient and graft survival improved in patients ...
R J, Ptachcinski +2 more
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Cyclosporine is an immunosuppressant used to prevent the rejection of transplanted kidneys, hearts, and livers. Cyclosporine suppresses T-lymphocyte function without causing myelosuppression, and its pharmacokinetics are highly variable. Compared with conventional immunosuppressive drug therapy, both patient and graft survival improved in patients ...
R J, Ptachcinski +2 more
openaire +2 more sources