Results 81 to 90 of about 3,841 (191)
Predictive Factors and Nomogram for Malignant Pulmonary Nodules (≤ 1 cm)
Canadian Respiratory Journal, Volume 2026, Issue 1, 2026.Introduction Models for predicting malignancy in pulmonary nodules ≤ 10 mm are lacking. This study aimed to identify predictive factors and develop a risk model for such nodules. Methods A retrospective cohort study analyzed 298 patients with pulmonary nodules ≤ 1 cm.
Zhenxin Cao +2 more
wiley +1 more source
Prognostic Role of Serum Cytokeratin-19 Fragment (CYFRA 21-1) in Patients with Hepatocellular Carcinoma [PDF]
, 2020 Keratin 19 (K19) is a cancer stem cell marker expressed by a subpopulation of hepatocellular carcinoma (HCC), associated with tumor aggressiveness. We evaluated the prognostic value of serum K19 fragment (CYFRA 21-1), in comparison or in combination with
Abate, Maria Lorena +12 more
core +1 more source
A Case Report of Short‐Term Metastasis After Surgery for Mammary Paget's Disease
Clinical Case Reports, Volume 13, Issue 12, December 2025.ABSTRACT Mammary Paget's disease (MPD) with ductal carcinoma in situ (DCIS) pathology can metastasize rapidly. HER2‐positive status likely drives aggression, warranting early postoperative systemic imaging and close surveillance. Anti‐HER2 agents require proactive toxicity management.
Chao Wang +6 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2008 目的探讨血清CYFRA21-1与NSE联合检测对肺癌的诊断价值。方法应用电化学发光免疫分析技术测定77例肺癌患者、22例肺部良性疾病患者和120例健康对照组血清CYFRA21-1、NSE的水平。结果肺癌患者血清CYFRA21-1、NSE水平明显高于肺部良性疾病组和健康对照组 ...
李兴华, 付艳, 赵云芳
doaj
Plasma next generation sequencing and droplet digital-qPCR-based quantification of circulating cell-free RNA for noninvasive early detection of cancer [PDF]
, 2020 Early detection of cancer holds high promise for reducing cancer-related mortality. Detection of circulating tumor-specific nucleic acids holds promise, but sensitivity and specificity issues remain with current technology.
Hegedüs, B. +3 more
core +1 more source
Cancer Reports, Volume 8, Issue 12, December 2025.ABSTRACT Background Epidermal growth factor receptor (EGFR) mutations are detected in approximately 40%–50% of patients with lung adenocarcinoma in Asian populations and in around 10% of patients in Western populations. Among these, the EGFR L861R mutation is uncommon and undetectable using conventional polymerase chain reaction methods.
Kei Kagawa +9 more
wiley +1 more source
评价CYFRA21-1、NSE和CEA对非小细胞肺癌的诊断价值
Zhongguo shiyan zhenduanxue, 2009 目的评价血清CYFRA21-1、NSE和CEA对非小细胞肺癌（NSCLC）辅助诊断的价值。方法检测178例NSCLC患者,98例良性肺疾病（BLD）患者和166例健康人血清中CYFRA21-1、NSE和CEA的浓度,CEA采用微粒子酶联免疫化学发光法,NSE和CYFRA21-1采用电化学发光法。结果三项血清肿瘤标志物（TM）在NSCLC中水平显著高于健康人和BLD患者。以健康人为对照组,特异性95%时,cut off值分别为CYFRA21-1 2.23μg/L,CEA 3.98μg/L,NSE20 ...
程黎明, 邓玲艳, 管青
doaj
细胞角蛋白19片段抗原21-1含量化学发光微粒子定量免疫检测方法的建立 [PDF]
, 2018 目的建立细胞角蛋白19片段抗原21-1(cytokeratin 19 fragment 21-1,CYFRA21-1,简称CY21-1)含量的化学发光微粒子免疫检测方法(chemiluminescent microparticle immunoassay,CMIA)。方法原核表达制备重组CY21-1(r CY21-1),用其免疫BALB/c小鼠后,收集小鼠脾脏细胞,常规杂交瘤技术与Sp2/0进行融合,制备CY21-1单抗。间接ELISA法筛选可稳定分泌CY21-1抗体的杂交瘤细胞,分别标记微性磁珠 ...
刘江武 +5 more
core +1 more source
Ocular Metastasis in Elderly Male Bladder Cancer Patients: Potential Risk Factors
American Journal of Men's Health, 2020 Bladder cancer is a common type of tumor among elderly male population; it causes intraocular metastasis (IOM). The study investigated the differences between elderly male bladder cancer patients with and without IOM, and identified risk factors for IOM.
Qian-Hui Xu +7 more
doaj +1 more source
Bioimaging and Bio-Sensing Techniques for Lung Cancer Detection [PDF]
, 2017 Early cancer detection and suitable treatment improve the 5-year survival rates of lung cancer significantly. Many cancer diagnostic approaches have been investigated, including mammography, magnetic resonance imaging, ultrasound, computerized tomography,
Wang, Lulu, Xu, Jinzhang
core +2 more sources