Results 61 to 70 of about 2,971 (159)

Integrating Clinical Features, Laboratory Biomarkers and Computed Tomography for the Discrimination of Non‐Small Cell Lung Cancer and Benign Pulmonary Diseases: A Clinical Prediction Model

Journal of Clinical Laboratory Analysis, Volume 40, Issue 4, February 2026.
This study developed and validated a clinical prediction model to differentiate non‐small cell lung cancer (NSCLC) from benign pulmonary diseases using clinical features, laboratory biomarkers, and CT features. The model achieved an AUC‐ROC of 0.95 in the training set and 0.82 in the validation set, demonstrating reliable diagnostic performance and ...
Jie Zhang, Shui Liu, Mingjian Bai, Fucun Ma, Guowei Liang, Bing Wang   +5 more
wiley   +1 more source

Distinction of ALK fusion gene‐ and EGFR mutation‐positive lung cancer with tumor markers

Thoracic Cancer
Background It is difficult to predict gene mutations individually based on clinical background alone. Tumor markers may help to predict each gene mutation.
Takahiro Akita, Ryo Ariyasu, Sho Kakuto, Keiki Miyadera, Ayu Kiritani, Ryosuke Tsugitomi, Yoshiaki Amino, Ken Uchibori, Satoru Kitazono, Noriko Yanagitani, Sadatomo Tasaka, Makoto Nishio   +11 more
doaj   +1 more source

Avaliação dos valores sérico e pleural dos marcadores tumorais CEA, CYFRA21-1 e CA 15-3 em portadores de derrame pleural Evaluation of serum and pleural levels of the tumor markers CEA, CYFRA21-1 and CA 15-3 in patients with pleural effusion

Jornal Brasileiro de Pneumologia, 2007
OBJETIVO: Dosar os marcadores tumorais antígeno carcinoembrionário (CEA), fragmento da citoqueratina 19 (CYFRA21-1) e antígeno glicosídico associado a tumor 15-3 (CA 15-3) em sangue e líquido pleural de portadores de derrames pleurais benignos e malignos,
Isabella Coimbra Wagner, Murilo José de Barros Guimarães, Lilian Karine Neves da Silva, Francisco Montenegro de Melo, Maria Tereza Cartaxo Muniz   +4 more
doaj   +1 more source

CD81 promotes proliferation and predicts survival in lung squamous cell carcinoma

Clinical and Translational Medicine, Volume 16, Issue 4, April 2026.
Ryu Kanzaki, Steven Reid, Paulina Bolivar, Sara Larsson, Yasushi Shintani, Kristian Pietras   +5 more
wiley   +1 more source

Non‐Destructively Quantifying the Whole‐Course Growth and Drug‐Response of PDOs by an Automatic Microfluidic System Utilizing Chemiluminescence Detection

Advanced Science, Volume 13, Issue 2, 9 January 2026.
The detection of secreted biomarkers enables molecular variations monitoring of organoid status. In this study, the non‐destructive quantification for the whole‐course growth and drug‐response of PDOs is first realized using a multifunctional microfluidic chip‐based system(ASMO) that integrates culturing, drug incubation, and biomarker detection ...
Yu Zhang, Daoyun Wang, Zhicheng Huang, Nan Zhang, Zhina Wang, Xin Wu, Anlan Zhang, Runzhi Yang, Tong Li, Zhibo Zheng, Yuxiao Lin, Naixin Liang, Zewen Wei   +12 more
wiley   +1 more source

评价CYFRA21-1、NSE和CEA对非小细胞肺癌的诊断价值

Zhongguo shiyan zhenduanxue, 2009
目的评价血清CYFRA21-1、NSE和CEA对非小细胞肺癌（NSCLC）辅助诊断的价值。方法检测178例NSCLC患者,98例良性肺疾病（BLD）患者和166例健康人血清中CYFRA21-1、NSE和CEA的浓度,CEA采用微粒子酶联免疫化学发光法,NSE和CYFRA21-1采用电化学发光法。结果三项血清肿瘤标志物（TM）在NSCLC中水平显著高于健康人和BLD患者。以健康人为对照组,特异性95%时,cut off值分别为CYFRA21-1 2.23μg/L,CEA 3.98μg/L,NSE20 ...
程黎明, 邓玲艳, 管青
doaj  

血清CYFRA21-1、NSE联合检测对肺癌诊断的临床意义

Zhongguo shiyan zhenduanxue, 2008
目的探讨血清CYFRA21-1与NSE联合检测对肺癌的诊断价值。方法应用电化学发光免疫分析技术测定77例肺癌患者、22例肺部良性疾病患者和120例健康对照组血清CYFRA21-1、NSE的水平。结果肺癌患者血清CYFRA21-1、NSE水平明显高于肺部良性疾病组和健康对照组 ...
李兴华, 付艳, 赵云芳
doaj  

Ocular Metastasis in Elderly Male Bladder Cancer Patients: Potential Risk Factors

American Journal of Men's Health, 2020
Bladder cancer is a common type of tumor among elderly male population; it causes intraocular metastasis (IOM). The study investigated the differences between elderly male bladder cancer patients with and without IOM, and identified risk factors for IOM.
Qian-Hui Xu, Qing Yuan, Yu-Qing Zhang, Biao Li, You-Lan Min, Qian-Min Ge, Rong-Bin Liang, Yi Shao   +7 more
doaj   +1 more source

Serum CYFRA 21-1 in Egyptian women with breast cancer

Alexandria Journal of Medicine, 2017
Introduction: Cytokeratin fragment 21.1 (CYFRA 21.1) assay detects a serum fragment of cytokeratin 19 (CK19) and is employed in the diagnosis and management of lung cancer, particularly of squamous cell histotype.
Samia A. Ebied, Wafaa M.E. Abdel-Rehim, Sanaa A. El-Benhawy, Mona A. El-Gawish, Mohamed A.A. Hassan, Islam I. El-Settawy   +5 more
doaj   +1 more source

血清miRNA-21与肿瘤标志物CEA、CYFRA21-1、NSE对早期非小细胞肺癌的诊断价值

Zhongguo shiyan zhenduanxue, 2017
目的探讨miRNA-21与CEA、CYFRA21-1、NSE对早期非小细胞肺癌（non-small cell lung cancer,NSCLC）的诊断价值。方法以50例NSCLC患者作为病例组、60例健康人为对照组,检测所有研究对象的血清癌胚抗原（CEA）、细胞角蛋白片段21-1（CYFRA21-1）、神经元特异性烯醇化酶（NSE）及miRNA-21（miR-21）水平。结果病例组血清CEA、NSE、CYFRA21-1、miR-21水平均显著高于对照组 ...
季禹乔, 孙明忠, 朱晖, 唐庆国, 王文才, 王进, 张灵芝, 吴芹芹   +7 more
doaj