Results 61 to 70 of about 3,930 (204)
Chinese Journal of Lung Cancer, 2010 Background and objective RECIST (Response Evaluation Criteria in Solid Tumors) criteria could not be used to detect viable tumor tissue and is not an accurate tool for evaluation of objective response (OR) in non-small cell lung cancer (NSCLC) patients ...
Chong'an XU +3 more
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Clinical and Translational Science, Volume 19, Issue 3, March 2026.ABSTRACT Circulating serum biomarkers have prognostic value in patients with advanced NSCLC, yet their potential still remains underappreciated at present. This review discusses classical approaches of biomarker data analysis, highlighting gaps, and summarizing current methodologies to evaluate the relationship between serum biomarkers and clinical ...
Francis Williams Ojara +6 more
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Cancer Medicine, Volume 15, Issue 2, February 2026.ABSTRACT Background Lung cancer remains the leading cause of cancer‐related mortality worldwide, highlighting the urgent need for earlier detection within real‐world screening and patient management pathways. Recent advances in multi‐omics technologies have created new opportunities for identifying biomarkers associated with early‐stage lung cancer ...
Fan Bu, Zhi‐Qiang Ling
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Test and Significance of CEA, NSE, CA125, CYFRA21-1 in Lung Cancer [PDF]
, 2017 目的 探讨CEA、NSE、CA125、CYFRA21-1在肺癌中的检测及意义.方法 回顾性分析2015年10月—2016年12月医院收治的肺部疾病患者166例,其中89例肺癌患者设为肺癌组,其余77例肺部良性病变患者设为肺部良性病变组.另选择35名健康志愿者作为健康对照组,电化学发光法检测3组血清中CEA、NSE、CA125、CYFRA21-1含量,分析单项及联合检测对肺癌的诊断价值.结果 肺癌组患者血清CEA、NSE、CA125、CYFRA21-1分别为（4.32±0.83）ng/mL、（11.54 ...
何佳瑜, 何正, 罗世翊, 魏玲
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Primary Mediastinal Malignant Melanoma Presenting With Pleural Effusion: A Case Report
Cancer Reports, Volume 9, Issue 2, February 2026.ABSTRACT Background Primary mediastinal malignant melanoma (PMMM) presenting with pleural effusion as the initial manifestation is exceedingly rare, presenting significant diagnostic and therapeutic challenges. This article reports a case of PMMM that initially manifested as pleural effusion and includes a review of the relevant literature.
Minlian Nong +4 more
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Technology in Cancer Research & TreatmentObjective: Finding biomarkers related to non-small cell lung cancer (NSCLC) is helpful for the diagnosis and precise treatment of lung cancer. The relationship between serum tumor M2-pyruvate kinase (TuM2-PK), carcinoembryonic antigen (CEA), and ...
Li Li MD +5 more
doaj +1 more source
腹腔镜结直肠癌根治术患者血清CYFRA21-1、CA724水平变化与复发转移的关系
Zhongguo shiyan zhenduanxue, 2021 目的探讨腹腔镜结直肠癌根治术患者血清细胞角蛋白19片段抗原(CYFRA21-1)、糖类抗原724(CA724)水平变化与复发转移的关系。方法选取2017年1月至2019年1月重庆市巴南区人民医院腹腔镜结直肠癌根治术患者120例,同期选取体检健康人员120例,所有人员均采用放射免疫法检测血清CYFRA21-1、CA724水平,分析血清CYFRA21-1、CA724水平变化与结直肠癌根治术后复发转移的关系。结果结直肠癌根治术患者血清CYFRA21-1、CA724水平明显高于健康人员 ...
汤红, 雷秀兵, 柴秀丽
doaj
Potential Diagnosis and Prognosis Value of Plasma MicroRNA-19a in Esophageal Cancer [PDF]
, 2015 背景：食管癌是发生于食管上皮组织的恶性肿瘤，具有高死亡率、高复发率和高转移率的特点。然而目前针对食管癌敏感的肿瘤标志物不多，且诊断效率较低，远远不能满足临床需求。MicroRNA是一类非编码RNA，可以稳定存在于人体血浆中并且易于检测。据报道，microRNA在诸多疾病状态下会出现表达异常，如食管癌、结直肠癌、肝癌等，这一发现极大地增加了血浆microRNA作为食管癌标志物的可能。在前期实验中，我们观察到microRNA-19a（miR-19a）在食管癌血浆标本中高表达，本文将重点探讨miR ...
白永颖
core
Journal of Clinical Laboratory Analysis, Volume 40, Issue 4, February 2026.This study developed and validated a clinical prediction model to differentiate non‐small cell lung cancer (NSCLC) from benign pulmonary diseases using clinical features, laboratory biomarkers, and CT features. The model achieved an AUC‐ROC of 0.95 in the training set and 0.82 in the validation set, demonstrating reliable diagnostic performance and ...
Jie Zhang +5 more
wiley +1 more source
CD81 promotes proliferation and predicts survival in lung squamous cell carcinoma
Clinical and Translational Medicine, Volume 16, Issue 4, April 2026.
Ryu Kanzaki +5 more
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