Results 61 to 70 of about 29,991,050 (179)
Clinical Significance of Serum Assay of CYFRA21-1 in Primary Lung Cancer.
Haigan, 1995 原発性肺癌における新しい腫瘍マーカーであるサイトケラチン19フラグメント (CYFRA21-1) の臨床的意義を検討するため原発性肺癌患者52例と他の肺疾患患者38例, 健常者22例について血清CYFRA21-1を測定し, 他の腫瘍マ-カー (CEA, SCC, NSE) と比較検討した.cut-off値を3.5ng/mlとすると原発性肺癌における陽性率は65%, 他の肺疾患における偽陽性率は8%であった.組織型別では, 扁平上皮癌で88.9%と最も高い陽性率を示し, 腺癌でも61.5%の陽性率を示した.免疫組織学的検討では扁平上皮癌において細胞質内で均一に強陽性に染色された.臨床病期別検討では, 1期50%, II期50%, IIIA期40%, IIIB期71%, IV期72 ...
Horiguchi, Takahiko +9 more
openaire +2 more sources
Molecular Genetics &Genomic Medicine, Volume 14, Issue 8, August 2026.The exploratory study examined whether Y chromosome haplogroups are potentially associated with ESCC in a male Chinese cohort. O2a1b and O1b1a showed nominal differences between patients and controls, but these signals were not robust after FDR correction. RNA‐seq suggested possible biological differences, which require validation in larger independent
Xueji Shi +7 more
wiley +1 more source
Advanced Sensor Research, Volume 5, Issue 7, July 2026.Breathomics is established as a non‐invasive diagnostic strategy by combining volatile organic compound biomarkers, nanomaterial‐based sensor arrays, and AI‐driven classification. Key diseases, sensing materials, and analytical challenges are critically compared, revealing how portable, data‐enabled breath platforms are moving toward clinically useful ...
Anesu Nyabadza +3 more
wiley +1 more source
Aggregate, Volume 7, Issue 7, July 2026.An AIEgen‐based immunotherapy paradigm that integrates rational photophysical engineering, high‐fidelity interrogation of immune–tumor interactions, and synergistic tumor immune microenvironment (TIME) remodeling is highlighted. Recent progress in molecular design, immune imaging, and combinational therapeutic strategies is summarized, together with ...
Xiangyu Tan +8 more
wiley +1 more source
Cancer Treatment and Research CommunicationsObjectives: The incidence of cervical cancer increases every year during pregnancy. Cervical cytology in pregnant women has a unique morphology and liquid-based cytology methods are prone to cause false positives. The aim of this study was to investigate
Qianlan Zhang +6 more
doaj +1 more source
腹腔镜结直肠癌根治术患者血清CYFRA21-1、CA724水平变化与复发转移的关系
Zhongguo shiyan zhenduanxue, 2021 目的探讨腹腔镜结直肠癌根治术患者血清细胞角蛋白19片段抗原(CYFRA21-1)、糖类抗原724(CA724)水平变化与复发转移的关系。方法选取2017年1月至2019年1月重庆市巴南区人民医院腹腔镜结直肠癌根治术患者120例,同期选取体检健康人员120例,所有人员均采用放射免疫法检测血清CYFRA21-1、CA724水平,分析血清CYFRA21-1、CA724水平变化与结直肠癌根治术后复发转移的关系。结果结直肠癌根治术患者血清CYFRA21-1、CA724水平明显高于健康人员 ...
汤红, 雷秀兵, 柴秀丽
doaj
Advanced Materials Technologies, Volume 11, Issue 12, 18 June 2026.ABSTRACT Electrochemical biosensors enable the accurate and timely detection of clinical biomarkers, improving healthcare and precision medicine. MXene nanosheets, a class of 2D transition metal carbides, nitrides, and carbonitrides, are promising materials for developing next‐generation electrochemical biosensors due to their unique physicochemical ...
Muhsin Ali +4 more
wiley +1 more source
CYFRA21-1和CEA对Ⅲ期非小细胞肺癌患者的临床预后意义
Zhongguo shiyan zhenduanxue, 2007 目的探讨CYFRA21-1和CEA对Ⅲ期非小细胞肺癌患者的临床预后意义。方法采用化学发光法检测62例Ⅲ期非小细胞肺癌患者放疗前与放疗结束时血清标本中CYFRA21-1和CEA的含量,临床随访6-24月。结果Ⅲ期非小细胞肺癌患者放疗结束时血清中CYFRA21-1和CEA的水平显著低于放疗前;放疗前血清中CYFRA21-1和CEA升高患者组的2年生存率与正常组2年生存率差异均无显著性意义;放疗结束时CYFRA21-1和CEA的水平正常组的两年生存率明显高于升高组;放疗结束时CYFRA21 ...
邓湘, 修霞, 谭爱国
doaj
Chinese Journal of Lung Cancer, 2016 Background and objective Due to it's concealment and no obvious symptoms, lung squamous carcimoma often has advanced disease when diagnosed. The aims of this study were to describe the characteristics of the disease, to evaluate the clinical importance ...
Ping LIANG, Junling LI
doaj +1 more source
, 2023 Laryngeal carcinoma (LC) is the second most common malignant tumor of the head and neck. Due to its insidious nature, most patients have developed to the middle and late stages by the time they are diagnosed, missing the best treatment period.
Xiaotao Bao +7 more
core +1 more source