Results 81 to 90 of about 3,930 (204)

Prognostic Role of Serum Cytokeratin-19 Fragment (CYFRA 21-1) in Patients with Hepatocellular Carcinoma [PDF]

, 2020
Keratin 19 (K19) is a cancer stem cell marker expressed by a subpopulation of hepatocellular carcinoma (HCC), associated with tumor aggressiveness. We evaluated the prognostic value of serum K19 fragment (CYFRA 21-1), in comparison or in combination with
Abate, Maria Lorena, Bugianesi, Elisabetta, Carucci, Patrizia, Caviglia, Gian Paolo, Ciruolo, Michela, Gaia, Silvia, Olivero, Antonella, Ribaldone, Davide Giuseppe, Risso, Alessandra, Rolle, Emanuela, Rosso, Chiara, Saracco, Giorgio Maria, Tandoi, Francesco   +12 more
core   +1 more source

Facile Scalable Assembly of Uniform and Layered Plasmonic Hotspots by Force‐Assisted Capillary‐Mediated Colloidal Transfer

Small, Volume 22, Issue 1, 2 January 2026.
This study presents a facile method to fabricate focal volume‐comparable and uniform 3D architectures of plasmonic hotspots by devising force‐assisted, capillary‐mediated stacking of colloidal metal nanoparticles for ultrasensitive molecular detections.
Ju A. La, Keumrai Whang, Hyunjoo Lee, Inhyeok Hwang, Youngjae Kim, Byeong Hyeon Choi, Hyungduk Ko, Hyun Koo Kim, Dan Dongeun Huh, Dongchoul Kim, Taewook Kang   +10 more
wiley   +1 more source

Distinction of ALK fusion gene‐ and EGFR mutation‐positive lung cancer with tumor markers

Thoracic Cancer
Background It is difficult to predict gene mutations individually based on clinical background alone. Tumor markers may help to predict each gene mutation.
Takahiro Akita, Ryo Ariyasu, Sho Kakuto, Keiki Miyadera, Ayu Kiritani, Ryosuke Tsugitomi, Yoshiaki Amino, Ken Uchibori, Satoru Kitazono, Noriko Yanagitani, Sadatomo Tasaka, Makoto Nishio   +11 more
doaj   +1 more source

SMARCA4‐Deficient Undifferentiated Thoracic Tumor: Clinical Features and Prognosis of a Case Series and Literature Review

The Clinical Respiratory Journal, Volume 20, Issue 1, January 2026.
Our manuscript presents detailed presentations of case series of thoracic SMARCA4‐UT, and we report a unique case of diaphragmatic metastases and, interestingly, the occurrence of brain metastasis in one patient, which is a rare phenomenon in SMARCA4‐UT.
Fangzhen Shan, Shuntao Liang, Youwen Zhang, Wei Wu, Guangxia Yang, Mei Yan, Xuemei Zhang, Yumao Miao, Linlin Liu, Jingjing Cai, Zhitao Shi, Bangdong Liu, Nannan Zhang   +12 more
wiley   +1 more source

Predictive Factors and Nomogram for Malignant Pulmonary Nodules (≤ 1 cm)

Canadian Respiratory Journal, Volume 2026, Issue 1, 2026.
Introduction Models for predicting malignancy in pulmonary nodules ≤ 10 mm are lacking. This study aimed to identify predictive factors and develop a risk model for such nodules. Methods A retrospective cohort study analyzed 298 patients with pulmonary nodules ≤ 1 cm.
Zhenxin Cao, Ying Zhu, Pierachille Santus   +2 more
wiley   +1 more source

评价CYFRA21-1、NSE和CEA对非小细胞肺癌的诊断价值

Zhongguo shiyan zhenduanxue, 2009
目的评价血清CYFRA21-1、NSE和CEA对非小细胞肺癌（NSCLC）辅助诊断的价值。方法检测178例NSCLC患者,98例良性肺疾病（BLD）患者和166例健康人血清中CYFRA21-1、NSE和CEA的浓度,CEA采用微粒子酶联免疫化学发光法,NSE和CYFRA21-1采用电化学发光法。结果三项血清肿瘤标志物（TM）在NSCLC中水平显著高于健康人和BLD患者。以健康人为对照组,特异性95%时,cut off值分别为CYFRA21-1 2.23μg/L,CEA 3.98μg/L,NSE20 ...
程黎明, 邓玲艳, 管青
doaj  

Multiomics Biomarkers for Differential Diagnosis of Pleural Effusion: Integration of Proteomic Markers and Single‐Cell Transcriptomics

Human Mutation, Volume 2026, Issue 1, 2026.
Background Differential diagnosis of pleural effusion remains challenging despite medical thoracoscopy (MT). We investigated whether integrating proteomic biomarkers with single‐cell transcriptomics and genomic mutation profiling could improve diagnostic accuracy and reveal mechanistic insights.
Zhengyou Zhang, Shaowei Zhan, Ying Tang, Zhougui Ling, Jinyan Wu, Dong Rui, Xiaomou Wei, Moyu Ming, Hao Chi   +8 more
wiley   +1 more source

血清CYFRA21-1、NSE联合检测对肺癌诊断的临床意义

Zhongguo shiyan zhenduanxue, 2008
目的探讨血清CYFRA21-1与NSE联合检测对肺癌的诊断价值。方法应用电化学发光免疫分析技术测定77例肺癌患者、22例肺部良性疾病患者和120例健康对照组血清CYFRA21-1、NSE的水平。结果肺癌患者血清CYFRA21-1、NSE水平明显高于肺部良性疾病组和健康对照组 ...
李兴华, 付艳, 赵云芳
doaj  

Ocular Metastasis in Elderly Male Bladder Cancer Patients: Potential Risk Factors

American Journal of Men's Health, 2020
Bladder cancer is a common type of tumor among elderly male population; it causes intraocular metastasis (IOM). The study investigated the differences between elderly male bladder cancer patients with and without IOM, and identified risk factors for IOM.
Qian-Hui Xu, Qing Yuan, Yu-Qing Zhang, Biao Li, You-Lan Min, Qian-Min Ge, Rong-Bin Liang, Yi Shao   +7 more
doaj   +1 more source

细胞角蛋白19片段抗原21-1含量化学发光微粒子定量免疫检测方法的建立 [PDF]

, 2018
目的建立细胞角蛋白19片段抗原21-1(cytokeratin 19 fragment 21-1,CYFRA21-1,简称CY21-1)含量的化学发光微粒子免疫检测方法(chemiluminescent microparticle immunoassay,CMIA)。方法原核表达制备重组CY21-1(r CY21-1),用其免疫BALB/c小鼠后,收集小鼠脾脏细胞,常规杂交瘤技术与Sp2/0进行融合,制备CY21-1单抗。间接ELISA法筛选可稳定分泌CY21-1抗体的杂交瘤细胞,分别标记微性磁珠 ...
刘江武, 王英雪, 翁祖星, 葛胜祥, 郭小怡, 陈毅歆   +5 more
core   +1 more source