Results 71 to 80 of about 3,930 (204)

Non‐Destructively Quantifying the Whole‐Course Growth and Drug‐Response of PDOs by an Automatic Microfluidic System Utilizing Chemiluminescence Detection

open access: yesAdvanced Science, Volume 13, Issue 2, 9 January 2026.
The detection of secreted biomarkers enables molecular variations monitoring of organoid status. In this study, the non‐destructive quantification for the whole‐course growth and drug‐response of PDOs is first realized using a multifunctional microfluidic chip‐based system(ASMO) that integrates culturing, drug incubation, and biomarker detection ...
Yu Zhang   +12 more
wiley   +1 more source

CYFRA21-1和CEA对Ⅲ期非小细胞肺癌患者的临床预后意义

open access: yesZhongguo shiyan zhenduanxue, 2007
目的探讨CYFRA21-1和CEA对Ⅲ期非小细胞肺癌患者的临床预后意义。方法采用化学发光法检测62例Ⅲ期非小细胞肺癌患者放疗前与放疗结束时血清标本中CYFRA21-1和CEA的含量,临床随访6-24月。结果Ⅲ期非小细胞肺癌患者放疗结束时血清中CYFRA21-1和CEA的水平显著低于放疗前;放疗前血清中CYFRA21-1和CEA升高患者组的2年生存率与正常组2年生存率差异均无显著性意义;放疗结束时CYFRA21-1和CEA的水平正常组的两年生存率明显高于升高组;放疗结束时CYFRA21 ...
邓湘, 修霞, 谭爱国
doaj  

Serum CYFRA21–1 and SCC-Ag levels in women during pregnancy and their diagnostic value for cervical cancer

open access: yesCancer Treatment and Research Communications
Objectives: The incidence of cervical cancer increases every year during pregnancy. Cervical cytology in pregnant women has a unique morphology and liquid-based cytology methods are prone to cause false positives. The aim of this study was to investigate
Qianlan Zhang   +6 more
doaj   +1 more source

Diagnosis of bone metastasis in patients with non-small cell lung cancer by combined detection of CEA, CYFRA21-1, and ALP [PDF]

open access: yesVojnosanitetski Pregled
Background/Aim. Despite significant advances in the diagnosis and treatment of non-small cell lung cancer (NSCLC), the overall prognosis remains poor, especially when bone metastasis occurs with disease progression.
Ye Haiying, Zhang Qiaoli
doaj   +1 more source

Cyfra 21-1 as a serum tumor marker for follow up of patients with laryngeal and hypopharyngeal squamous cell carcinoma [PDF]

open access: yes, 2009
AIM: To evaluate the importance and potential of Cyfra21-1 as a tumor marker (TM) for follow-up of patients with squamous cell carcinoma (SCC) in laryngeal and hypopharyngeal cancer.
Al-Shagahin, Hani
core   +1 more source

Significance of Serum Tumor Markers in Esophageal and Gastric Cancers: A Systematic Literature Review

open access: yesAnnals of Gastroenterological Surgery, Volume 10, Issue 1, Page 54-66, January 2026.
The utility of serum tumor markers in esophageal squamous cell carcinoma and gastric cancer were evaluated by systematic review and meta‐analysis. In addition, the position of each marker, strategies for improving their accuracy in the future, and new markers are also described.
Yasunori Matsumoto   +2 more
wiley   +1 more source

Clean Colorectum at Diagnostic Colonoscopy:Subsequent Detection of Extracolonic Malignancies by Plasma Protein Biomarkers? [PDF]

open access: yes, 2018
Introduction: Most of the subjects undergoing diagnostic colonoscopy do not have neoplastic bowel lesions. Potentially, some of the symptoms may therefore be caused by extracolonic malignancy, and subjects with persisting symptoms may need subsequent ...
Christensen, Ib J   +14 more
core   +1 more source

Aggregation‐induced emission luminogens in in vitro diagnostics: Advancing biomarker detection in body fluids

open access: yesInterdisciplinary Medicine, Volume 4, Issue 1, January 2026.
This review systematically summarizes recent advances in aggregation‐induced emission (AIE) materials for in vitro diagnostics (IVD). It highlights probe design strategies—categorizing them into direct‐responsive, indirect‐responsive, and nano‐immunoprobes—and their applications in detecting a wide range of biomarkers across diverse body fluids ...
Qi Liu   +5 more
wiley   +1 more source

Nanotechnology‐Enhanced Approaches for Early Cancer Diagnosis

open access: yesNano Select, Volume 7, Issue 1, January 2026.
Conventional MRI and PET provide limited sensitivity and contrast for precise brain lesion detection. In contrast, radiolabeled nanoparticlebased PET imaging enables enhanced signal specificity and sensitivity. By integrating multifunctional nanoprobes, this platform improves multimodal imaging performance, allowing more accurate visualization of ...
Jongmoo Lee   +5 more
wiley   +1 more source

Clinical Significance of Tumor Marker Detection in Patients 
with Advanced Squamous Cell Carcimoma of the Lung

open access: yesChinese Journal of Lung Cancer, 2016
Background and objective Due to it's concealment and no obvious symptoms, lung squamous carcimoma often has advanced disease when diagnosed. The aims of this study were to describe the characteristics of the disease, to evaluate the clinical importance ...
Ping LIANG, Junling LI
doaj   +1 more source

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