Results 51 to 60 of about 2,971 (159)

腹腔镜结直肠癌根治术患者血清CYFRA21-1、CA724水平变化与复发转移的关系

Zhongguo shiyan zhenduanxue, 2021
目的探讨腹腔镜结直肠癌根治术患者血清细胞角蛋白19片段抗原(CYFRA21-1)、糖类抗原724(CA724)水平变化与复发转移的关系。方法选取2017年1月至2019年1月重庆市巴南区人民医院腹腔镜结直肠癌根治术患者120例,同期选取体检健康人员120例,所有人员均采用放射免疫法检测血清CYFRA21-1、CA724水平,分析血清CYFRA21-1、CA724水平变化与结直肠癌根治术后复发转移的关系。结果结直肠癌根治术患者血清CYFRA21-1、CA724水平明显高于健康人员 ...
汤红, 雷秀兵, 柴秀丽
doaj  

An Extracellular Vesicle Protein‐Based Machine Learning Framework for Early Detection of Oesophageal Squamous Cell Carcinoma: A Multicentre, Prospective Study

Journal of Extracellular Vesicles, Volume 15, Issue 3, March 2026.
ABSTRACT Early detection of oesophageal squamous cell carcinoma (ESCC) is critical for improving survival, yet current screening is hampered by the lack of effective, non‐invasive methods. Here, we developed and prospectively validated an extracellular vesicle (EV) protein‐based blood test for the preclinical detection of ESCC.
Yu Wang, Shan Xing, Ya‐Xian Wu, Ning Xue, Pei‐Min Chen, Run‐Xian Jin, Yi‐Wei Xu, Ming‐Fang Ji, Yu‐Hui Peng, Yuan‐Tao Liu, Li‐Na Chen, Meng Wu, Zi‐Ying Jiang, Shang‐Hang Xie, Yi‐Ling Luo, Biao Zhang, Xin‐Yuan Ou, Qi Huang, Bo‐Yu Tian, Li Ling, Su‐Mei Cao, Wan‐Li Liu, Mu‐Sheng Zeng, Qian Zhong   +23 more
wiley   +1 more source

CYFRA21-1和CEA对Ⅲ期非小细胞肺癌患者的临床预后意义

Zhongguo shiyan zhenduanxue, 2007
目的探讨CYFRA21-1和CEA对Ⅲ期非小细胞肺癌患者的临床预后意义。方法采用化学发光法检测62例Ⅲ期非小细胞肺癌患者放疗前与放疗结束时血清标本中CYFRA21-1和CEA的含量,临床随访6-24月。结果Ⅲ期非小细胞肺癌患者放疗结束时血清中CYFRA21-1和CEA的水平显著低于放疗前;放疗前血清中CYFRA21-1和CEA升高患者组的2年生存率与正常组2年生存率差异均无显著性意义;放疗结束时CYFRA21-1和CEA的水平正常组的两年生存率明显高于升高组;放疗结束时CYFRA21 ...
邓湘, 修霞, 谭爱国
doaj  

Early Cancer Detection: What's Going on and What's Next

MedComm, Volume 7, Issue 3, March 2026.
Multicancer early detection (MCED) platforms have emerged as a promising strategy for the safe and effective early detection of multiple cancer types, with the potential to reduce metastatic burden and improve clinical outcomes, particularly for aggressive malignancies that lack effective population‐level screening.
Emma Di Carlo
wiley   +1 more source

Elevated Squamous Cell Carcinoma Antigen, Cytokeratin 19 Fragment, and Carcinoembryonic Antigen Levels in Diabetic Nephropathy

International Journal of Endocrinology, 2017
Objective. We aimed to explore whether squamous cell carcinoma antigen (SCC), cytokeratin 19 fragment (Cyfra21-1), neuron-specific enolase (NSE), and carcinoembryonic antigen (CEA) are elevated in diabetic nephropathy (DN) and the association between ...
Jianzhong Chen, Feng Tao, Bin Zhang, Qingguang Chen, Yan Qiu, Qian Luo, Yanna Gen, Jiali Meng, Jue Zhang, Hao Lu   +9 more
doaj   +1 more source

Diagnosis of bone metastasis in patients with non-small cell lung cancer by combined detection of CEA, CYFRA21-1, and ALP [PDF]

Vojnosanitetski Pregled
Background/Aim. Despite significant advances in the diagnosis and treatment of non-small cell lung cancer (NSCLC), the overall prognosis remains poor, especially when bone metastasis occurs with disease progression.
Ye Haiying, Zhang Qiaoli
doaj   +1 more source

Review of Existing Approaches and Potential Role of Pharmacometrics in the Interpretation of Prognostic Circulating Serum Biomarkers in Advanced NSCLC

Clinical and Translational Science, Volume 19, Issue 3, March 2026.
ABSTRACT Circulating serum biomarkers have prognostic value in patients with advanced NSCLC, yet their potential still remains underappreciated at present. This review discusses classical approaches of biomarker data analysis, highlighting gaps, and summarizing current methodologies to evaluate the relationship between serum biomarkers and clinical ...
Francis Williams Ojara, Yomna M. Nassar, Kimberly Geiger, Madele van Dyk, Stefan Holdenrieder, Markus Joerger, Charlotte Kloft   +6 more
wiley   +1 more source

Clinical Significance of Tumor Marker Detection in Patients 
with Advanced Squamous Cell Carcimoma of the Lung

Chinese Journal of Lung Cancer, 2016
Background and objective Due to it's concealment and no obvious symptoms, lung squamous carcimoma often has advanced disease when diagnosed. The aims of this study were to describe the characteristics of the disease, to evaluate the clinical importance ...
Ping LIANG, Junling LI
doaj   +1 more source

Digital Biomarkers for Precision Early Detection of Lung Cancer: Integrating AI‐Driven Multi‐Omics Into Clinical Pathways

Cancer Medicine, Volume 15, Issue 2, February 2026.
ABSTRACT Background Lung cancer remains the leading cause of cancer‐related mortality worldwide, highlighting the urgent need for earlier detection within real‐world screening and patient management pathways. Recent advances in multi‐omics technologies have created new opportunities for identifying biomarkers associated with early‐stage lung cancer ...
Fan Bu, Zhi‐Qiang Ling
wiley   +1 more source

Primary Mediastinal Malignant Melanoma Presenting With Pleural Effusion: A Case Report

Cancer Reports, Volume 9, Issue 2, February 2026.
ABSTRACT Background Primary mediastinal malignant melanoma (PMMM) presenting with pleural effusion as the initial manifestation is exceedingly rare, presenting significant diagnostic and therapeutic challenges. This article reports a case of PMMM that initially manifested as pleural effusion and includes a review of the relevant literature.
Minlian Nong, Weifeng Wei, Naijian Li, Yunxiang Zeng, Jinlin Wang   +4 more
wiley   +1 more source