Results 51 to 60 of about 29,991,050 (179)

Human biomarker navigator

open access: yesiMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li   +29 more
wiley   +1 more source

Pragmatic Screening for Sarcopenia in Non‐Small Cell Lung Cancer: Development and Internal Validation of a Prospective Risk Model Integrating T12 CT Indices and Routine Clinical Variables

open access: yesCancer Medicine, Volume 15, Issue 10, October 2026.
ABSTRACT Background Sarcopenia or low muscle mass is common in non‐small cell lung cancer and predicts poorer outcomes, but its assessment typically relies on CT‐based skeletal muscle index at the L3 vertebral level. Standard chest CTs often omit the L3 level, leaving many patients without a straightforward muscle mass measure, so sarcopenia frequently
Zhuorui You   +10 more
wiley   +1 more source

Painless Biosensing for Non‐Invasive Health Monitoring: Advances, Platforms and Future Directions

open access: yesElectrochemical Science Advances, Volume 6, Issue 5, October 2026.
ABSTRACT Non‐invasive biosensing has expanded blood‐based diagnostics into a growing set of accessible peripheral biofluids, yet most existing reviews remain confined to sweat, tears, saliva and urine, and treat the underlying literature descriptively rather than critically.
Ayub Alam   +10 more
wiley   +1 more source

Clinical Significance of Serum Cytokeratin 19 Fragment in the Prediction of Chemotherapy Efficacy and Prognosis in Patients with Advanced Non-small Cell Lung Cancer

open access: yesChinese Journal of Lung Cancer, 2010
Background and objective RECIST (Response Evaluation Criteria in Solid Tumors) criteria could not be used to detect viable tumor tissue and is not an accurate tool for evaluation of objective response (OR) in non-small cell lung cancer (NSCLC) patients ...
Chong'an XU   +3 more
doaj  

Evaluation of serum CEA, CYFRA21-1 and CA125 for the early detection of colorectal cancer using longitudinal preclinical samples [PDF]

open access: yes, 2015
Blood-borne biomarkers for early detection of colorectal cancer (CRC) could markedly increase screening uptake. The aim of this study was to evaluate serum carcinoembryonic antigen (CEA), CYFRA21-1 and CA125 for the early detection of CRC in an ...
J F Timms   +19 more
core   +1 more source

PD‐L1 Tumour‐Cell/Immune‐Cell Phenotype, Early Nodal Status and Serum Biomarkers in Locally Advanced Head and Neck Squamous Cell Carcinoma Receiving Neoadjuvant Therapy: A Retrospective Cohort Study With Exploratory Survival Analysis

open access: yesCancer Medicine, Volume 15, Issue 9, September 2026.
ABSTRACT PD‐L1 tumour‐cell (TC) and immune‐cell (IC) expression are scored separately in head and neck squamous cell carcinoma (HNSCC) but are often collapsed into a combined positive score, potentially obscuring distinct patterns. In this retrospective, single‐centre cohort of 61 patients with locally advanced, hypopharynx‐predominant HNSCC receiving ...
Ningning Wang, Zehui Yun, Fangli Cao
wiley   +1 more source

Real‐World Prognostic Analysis of Clinical Characteristics in Extensive‐Stage Small Cell Lung Cancer: A Nomogram for Survival Prediction in Patients Receiving First‐Line Immunochemotherapy With Serplulimab

open access: yesCancer Medicine, Volume 15, Issue 8, August 2026.
Among 239 patients reviewed, 109 patients with extensive‐stage small‐cell lung cancer receiving first‐line serplulimab‐based immunochemotherapy were included. A nomogram incorporating liver metastasis, maintenance therapy, albumin, and neutrophil‐to‐lymphocyte ratio predicted overall survival and significantly stratified patients into three risk groups
Ying Zhu   +6 more
wiley   +1 more source

Too Old for Surgery? A Case Report of an Octogenarian Patient With Locally Advanced Lung Cancer Achieving Long‐Term Survival via Bilobectomy Followed by Adjuvant Targeted Therapy

open access: yesCancer Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background An increasing number of octogenarian patients are being diagnosed with lung cancer, but they are less likely to receive surgery because of fragility. As a result, the optimal management of lung cancer in octogenarians remains unclear.
Han‐Yu Deng   +3 more
wiley   +1 more source

The important role of circulating CYFRA21-1 in metastasis diagnosis and prognostic value compared with carcinoembryonic antigen and neuron-specific enolase in lung cancer patients

open access: yes, 2017
Background The roles of carcinoembryonic antigen (CEA), cytokeratin 19 fragments (CYFRA21-1) and neuron-specific enolase (NSE) in metastases occurrence and poor diagnosis in specific histological classifications of lung cancer need ...
Zhao, Shuang   +27 more
core   +1 more source

Association of Serum Levels of Fibroblast Growth Factor Receptor-3 and Cytokeratin-19 with Invasive and Non-invasive Bladder Cancer in a Sample of the Iraqi Population

open access: yesThe Iraqi Journal of Medical Sciences
Background    Bladder cancer (BC) is the tenth most prevalent cancer worldwide. The fibroblast growth factor receptor 3 (FGFR3) controls essential signaling pathways that govern several cellular processes, including proliferation and migration ...
Hasan N. Smeasm   +2 more
doaj   +1 more source

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