Results 31 to 40 of about 2,971 (159)
Life, 2021 Radon is a major cause of lung cancer (LC) deaths among non-smokers worldwide. However, no serum biomarker for screening of LC risk in high residential radon (HRR) areas is available. Therefore, the aim of this study was to determine diagnostic values of
Narongchai Autsavapromporn +7 more
doaj +1 more source
CYFRA21-1 levels could be a biomarker for bladder cancer: a meta-analysis
Genetics and Molecular Research, 2015 The proteolytic region of cytokeratin-19, referred to as CYFRA21-1, is a soluble molecule present in the serum and other body fluids, and is considered a tumor marker in several neoplastic diseases. To examine whether urinary or serum samples containing CYFRA21-1 can be used as biomarkers for bladder cancer, we conducted a comprehensive meta-analysis ...
L I, Kuang +4 more
openaire +2 more sources
Mechanisms of the release of CYFRA21-1 in human lung cancer cell lines
Lung Cancer, 2000 The CYFRA 21-1 assay which detects cytokeratin 19 (CK19) fragment is widely used as a tumor marker for lung cancer. However, the reason why some lung cancer cell lines release CK19 fragment in culture supernatants and others do not, remains unclear. It was hypothesized that the release of CK19 fragment may be elucidated by the expression of mRNA for ...
K, Dohmoto +8 more
openaire +3 more sources
Cancer Medicine, Volume 15, Issue 8, August 2026.Among 239 patients reviewed, 109 patients with extensive‐stage small‐cell lung cancer receiving first‐line serplulimab‐based immunochemotherapy were included. A nomogram incorporating liver metastasis, maintenance therapy, albumin, and neutrophil‐to‐lymphocyte ratio predicted overall survival and significantly stratified patients into three risk groups
Ying Zhu +6 more
wiley +1 more source
Cancer Reports, Volume 9, Issue 8, August 2026.ABSTRACT Background An increasing number of octogenarian patients are being diagnosed with lung cancer, but they are less likely to receive surgery because of fragility. As a result, the optimal management of lung cancer in octogenarians remains unclear.
Han‐Yu Deng +3 more
wiley +1 more source
Molecular Genetics &Genomic Medicine, Volume 14, Issue 8, August 2026.The exploratory study examined whether Y chromosome haplogroups are potentially associated with ESCC in a male Chinese cohort. O2a1b and O1b1a showed nominal differences between patients and controls, but these signals were not robust after FDR correction. RNA‐seq suggested possible biological differences, which require validation in larger independent
Xueji Shi +7 more
wiley +1 more source
Advanced Sensor Research, Volume 5, Issue 7, July 2026.Breathomics is established as a non‐invasive diagnostic strategy by combining volatile organic compound biomarkers, nanomaterial‐based sensor arrays, and AI‐driven classification. Key diseases, sensing materials, and analytical challenges are critically compared, revealing how portable, data‐enabled breath platforms are moving toward clinically useful ...
Anesu Nyabadza +3 more
wiley +1 more source
Aggregate, Volume 7, Issue 7, July 2026.An AIEgen‐based immunotherapy paradigm that integrates rational photophysical engineering, high‐fidelity interrogation of immune–tumor interactions, and synergistic tumor immune microenvironment (TIME) remodeling is highlighted. Recent progress in molecular design, immune imaging, and combinational therapeutic strategies is summarized, together with ...
Xiangyu Tan +8 more
wiley +1 more source
Journal of Translational Medicine, 2012 Background The purpose of this study is to evaluate the predictive significance of preoperative serum level of cytokeratin 19 fragments (Cyfra21-1) and squamous cell carcinoma antigen (SCC-Ag) after complete resection in patients with stage II esophageal
Cao Xun +7 more
doaj +1 more source
Advanced Materials Technologies, Volume 11, Issue 12, 18 June 2026.ABSTRACT Electrochemical biosensors enable the accurate and timely detection of clinical biomarkers, improving healthcare and precision medicine. MXene nanosheets, a class of 2D transition metal carbides, nitrides, and carbonitrides, are promising materials for developing next‐generation electrochemical biosensors due to their unique physicochemical ...
Muhsin Ali +4 more
wiley +1 more source