Results 21 to 30 of about 2,971 (159)

Diagnostic value analysis of combined detection of Trx, CYFRA21-1 and SCCA in lung cancer. [PDF]

Oncol Lett, 2019
The expression levels of thioredoxin (Trx), cytokeratin fragment 21-1 (CYFRA21-1) and serum squamous cell carcinoma antigen (SCCA) in patients with lung cancer and the diagnostic value of combined detection were investigated. Sixty-five patients with lung cancer in Weihai Municipal Hospital from January 2014 to June 2017 were retrospectively selected ...
Qu T, Zhang J, Xu N, Liu B, Li M, Liu A, Li A, Tang H.   +7 more
europepmc   +4 more sources

Usefulness of Circulating CYFRA21-1 in Patients as a Biomarker in Patients Taking Sorafenib or Lenvatinib for Unresectable Hepatocellular Carcinoma

Reports, 2021
Background: This study investigated the impact of serum cytokeratin 19 fragment (CYFRA21-1) level on the clinical outcomes of patients with unresectable hepatocellular carcinoma (HCC) treated with sorafenib (SOR) or lenvatinib (LEN).
Hitomi Takada, Leona Osawa, Yasuyuki Komiyama, Ryoh Kato, Natsuko Nakakuki, Masaru Muraoka, Yuichiro Suzuki, Akihisa Tatsumi, Mitsuaki Sato, Ei Takahashi, Shinichi Takano, Mitsuharu Fukasawa, Tatsuya Yamaguchi, Taisuke Inoue, Shinya Maekawa, Nobuyuki Enomoto   +15 more
doaj   +1 more source

Diagnostic Accuracy of CYFRA21-1 in the Differential Diagnosis of Pleural Effusions [PDF]

Anticancer Research, 2019
Approximately 20% of pleural effusions are associated with cancer; about 50% require invasive procedures to perform diagnosis. Determination of the concentration of soluble cytokeratin 19-fragments (CYFRA21-1) may help identify patients with malignant effusions. However, pathologies other than cancer can increase its concentration.
Jaume, Trapé, Francesc, Sant, Jesus, Montesinos, Anna, Arnau, Maria, Sala, Oscar, Bernadich, Esperanza, Martín, Damia, Perich, Joan, Lopez, Sandra, Ros, Enrique, Esteve-Valverde, Rafael, Pérez, Carolina, González-Fernández, Jordi, Aligue, Silvia, Catot, Montserrat, Domenech, Domingo, Ruiz, Mariona, Bonet, Rafael, Molina, Josep, Ordeig   +19 more
openaire   +2 more sources

Increases in Serum CYFRA21-1 Concentration during Successful Treatment with Crizotinib [PDF]

American Journal of Case Reports, 2014
Increases in tumor marker concentrations usually suggest disease progression.We here describe on 3 patients with non-small cell lung cancer whose serum concentrations of CYFRA21-1 increased in spite of successful treatment with crizotinib. Discontinuation of crizotinib resulted in a rapid decrease in serum CYFRA21-1 concentrations in all cases.
Kanaji, Nobuhiro, Tadokoro, Akira, Watanabe, Naoki, Inoue, Takuya, Ishii, Tomoya, Dobashi, Hiroaki, Bandoh, Shuji   +6 more
openaire   +2 more sources

Variations in Serum CEA and CYFRA21-1 Levels Before and After Surgery Facilitate Prognosis of Non-small Cell Lung Cancer Patients

Chinese Journal of Lung Cancer, 2015
Background and objective Serum carcinoembryonic antigen (CEA) and the soluble fragment of cytokeratin 19 (CYFRA21-1) are important tumor markers (TMs) in the preoperative examination of patients with non-small cell lung cancer (NSCLC).
Xinchun DUAN, Yong CUI, Min GONG, Feng TIAN, Guan SHI, Bingqun WU, Mingliang LIU, Jiayun GUO, Yuanyuan KONG   +8 more
doaj   +1 more source

Fine-needle aspirates CYFRA 21-1 is a useful tumor marker for detecting axillary lymph node metastasis in breast cancer patients. [PDF]

PLoS ONE, 2013
INTRODUCTION: To assess whether the value of CYFRA21-1 in the aspirates of ultrasonography-guided fine-needle aspiration biopsy (US-FNAB) can contribute to improving the performances of US-FNAB in the diagnosis of axillary lymph node (LN) metastasis in ...
Jung Hyun Yoon, Kyung Hwa Han, Eun-Kyung Kim, Hee Jung Moon, Min Jung Kim, Young Joo Suh, Ji Soo Choi, Byeong-Woo Park   +7 more
doaj   +1 more source

Serum CYFRA21-1 is Correlated with the Efficacy of Epidermal Growth Factor Receptor-tyrosine Kinase Inhibitor in Non-small Cell Lung Cancer Patients Harboring EGFR Mutations

Chinese Journal of Lung Cancer, 2016
Background and objective Epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) are the standard first-line treatment regimen for EGFR mutated non-small cell lung cancer (NSCLC) patients. However, the efficacy of EGFR-TKIs widely varies.
Qunhui WANG, Hua ZHENG, Fanbin HU, Hongmei ZHANG, Ying HU, Jie LI, Tongmei ZHANG, Zan LIU, Baohua LU, Aimin HU, Baolan LI   +10 more
doaj   +1 more source

Serum cyfra21-1 as a biomarker in patients with nonsmall cell lung cancer

Journal of Cancer Research and Therapeutics, 2014
The purpose of this retrospective study was to evaluate the clinical value of serum cytokeratin-19-fragment (cyfra21-1) as a biomarker in nonsmall cell lung cancer (NSCLC).Sixty-six patients with NSCLC and 48 cases with benign lung disease were retrospectively analyzed in the department of thoracic surgery in our hospital.
Hongjie, Zhao, Xuejun, Shi, Jinbo, Liu, Zhengang, Chen, Guangshun, Wang   +4 more
openaire   +2 more sources

Predictive significance of CYFRA21-1, squamous cell carcinoma antigen and carcinoembryonic antigen for lymph node metastasis in patients with esophageal squamous cancer

The International Journal of Biological Markers, 2019
From January 2018 to May 2018, 108 patients with thoracic esophageal cancer underwent esophagectomy with two- to three-field lymph node dissection.
Xinyu Mei, Xiaodong Zhu, Lei Zuo, Hanran Wu, Mingfa Guo, Changqing Liu   +5 more
doaj   +1 more source

Serum CYFRA21-1 as an effective tumor biomarker for patients with nasopharyngeal carcinoma

Neoplasma, 2015
We investigated if the serum cytokeratin 19 fragment 21.1 (CYFRA21-1) level was elevated in nasopharyngeal carcinoma (NPC) and can function as a biomarker for detection and monitoring of NPC. Three hundred and one study subjects were divided into two groups: the NPC group (n=126) and healthy control group (n=175).
X M, Song, S Z, Wang, Z J, Wang, W J, Cao, J, L, F, Chen   +5 more
openaire   +3 more sources