Results 41 to 50 of about 21,238,241 (185)

Diagnostic Significance of Combining Telomerase Activity with CYFRA21-1 Level in Differentiating Malignant Pleural Effusion Caused by Lung Cancer from Benign Pleural Effusio

Chinese Journal of Lung Cancer, 2010
Background and objective Telomerase and CYFRA21-1 may be positively expressed in malignant pleural effusion, but the sensitivity and specificity of single tumor marker were low.
Hongmei LI, Junhua FU, Yuande XIU, Qinghua ZHOU   +3 more
doaj   +1 more source

Distinction of ALK fusion gene‐ and EGFR mutation‐positive lung cancer with tumor markers [PDF]

Thoracic Cancer
Background It is difficult to predict gene mutations individually based on clinical background alone. Tumor markers may help to predict each gene mutation.
Takahiro Akita, Ryo Ariyasu, Sho Kakuto, Keiki Miyadera, Ayu Kiritani, Ryosuke Tsugitomi, Yoshiaki Amino, Ken Uchibori, Satoru Kitazono, Noriko Yanagitani, Sadatomo Tasaka, Makoto Nishio   +11 more
doaj   +2 more sources

Highly sensitive detection of CYFRA21-1 with a SERS sensing platform based on the MBs enrichment strategy and antibody-DNA-mediated CHA amplification. [PDF]

Front Bioeng Biotechnol, 2023
Laryngeal carcinoma (LC) is the second most common malignant tumor of the head and neck. Due to its insidious nature, most patients have developed to the middle and late stages by the time they are diagnosed, missing the best treatment period.
Bao X, Wang S, Liu X, Li G.
europepmc   +2 more sources

Identification of EGFR mutation status in male patients with non-small-cell lung cancer: role of ¹⁸F-FDG PET/CT and serum tumor markers CYFRA21-1 and SCC-Ag. [PDF]

EJNMMI Res, 2023
Background The high incidence of epidermal growth factor receptor (EGFR) mutations is usually found in female patients with lung adenocarcinoma who have never-smoked. However, reports concerning male patients are scarce. Thus, this study aimed to explore
Jiang M, Chen P, Guo X, Zhang X, Gao Q, Zhang J, Zhao G, Zheng J.   +7 more
europepmc   +2 more sources

Diagnostic Accuracy of CYFRA21-1 in the Differential Diagnosis of Pleural Effusions [PDF]

Anticancer Research, 2019
Approximately 20% of pleural effusions are associated with cancer; about 50% require invasive procedures to perform diagnosis. Determination of the concentration of soluble cytokeratin 19-fragments (CYFRA21-1) may help identify patients with malignant effusions. However, pathologies other than cancer can increase its concentration.
Jaume, Trapé, Francesc, Sant, Jesus, Montesinos, Anna, Arnau, Maria, Sala, Oscar, Bernadich, Esperanza, Martín, Damia, Perich, Joan, Lopez, Sandra, Ros, Enrique, Esteve-Valverde, Rafael, Pérez, Carolina, González-Fernández, Jordi, Aligue, Silvia, Catot, Montserrat, Domenech, Domingo, Ruiz, Mariona, Bonet, Rafael, Molina, Josep, Ordeig   +19 more
openaire   +2 more sources

Diagnostic utility of LDH, CA125 and CYFRA21-1 in tuberculosis pleural effusion

Medicina Clínica, 2022
The aim of this study was to assess the diagnostic value of several markers for tuberculosis pleural effusion (TPE) using the combined analysis of Lactate dehydrogenase (LDH), Carbohydrate antigen 125 (CA125), Cytokeratin-19 fragment (CYFRA21-1).From January to December in 2018, a total of 37 patients with pleural effusion (22 cases of transudative ...
Hongxia, Lin, Lei, Ni
openaire   +2 more sources

Increases in Serum CYFRA21-1 Concentration during Successful Treatment with Crizotinib [PDF]

American Journal of Case Reports, 2014
Increases in tumor marker concentrations usually suggest disease progression.We here describe on 3 patients with non-small cell lung cancer whose serum concentrations of CYFRA21-1 increased in spite of successful treatment with crizotinib. Discontinuation of crizotinib resulted in a rapid decrease in serum CYFRA21-1 concentrations in all cases.
Kanaji, Nobuhiro, Tadokoro, Akira, Watanabe, Naoki, Inoue, Takuya, Ishii, Tomoya, Dobashi, Hiroaki, Bandoh, Shuji   +6 more
openaire   +2 more sources

Test and Significance of CEA, NSE, CA125, CYFRA21-1 in Lung Cancer [PDF]

, 2017
目的 探讨CEA、NSE、CA125、CYFRA21-1在肺癌中的检测及意义.方法 回顾性分析2015年10月—2016年12月医院收治的肺部疾病患者166例,其中89例肺癌患者设为肺癌组,其余77例肺部良性病变患者设为肺部良性病变组.另选择35名健康志愿者作为健康对照组,电化学发光法检测3组血清中CEA、NSE、CA125、CYFRA21-1含量,分析单项及联合检测对肺癌的诊断价值.结果 肺癌组患者血清CEA、NSE、CA125、CYFRA21-1分别为（4.32±0.83）ng/mL、（11.54 ...
魏玲, 何正, 罗世翊, 何佳瑜
core   +1 more source

Antigen-Down PEC Immunosensor for CYFRA21‑1 Detection Based on Photocurrent Polarity Switching Strategy

, 2022
In this work, an antigen-down photoelectrochemical (PEC) immunosensor based on a signal polarity switching strategy for the detection of cytokeratin 19 fragment 21-1 (CYFRA21-1) was proposed.
Jinxiu Zhao (4507333), Xiang Ren (358465), Xiaodong Xue (582390), Huangxian Ju (392237), Jinhuan Zhang (740758), Hongmin Ma (625034), Qin Wei (1482154), Yizhen Du (12371752)   +7 more
core   +1 more source

Serum cyfra21-1 as a biomarker in patients with nonsmall cell lung cancer

Journal of Cancer Research and Therapeutics, 2014
The purpose of this retrospective study was to evaluate the clinical value of serum cytokeratin-19-fragment (cyfra21-1) as a biomarker in nonsmall cell lung cancer (NSCLC).Sixty-six patients with NSCLC and 48 cases with benign lung disease were retrospectively analyzed in the department of thoracic surgery in our hospital.
Hongjie, Zhao, Xuejun, Shi, Jinbo, Liu, Zhengang, Chen, Guangshun, Wang   +4 more
openaire   +2 more sources