Results 41 to 50 of about 2,971 (159)

Clinical Significance of Serum Cytokeratin 19 Fragment in the Prediction of Chemotherapy Efficacy and Prognosis in Patients with Advanced Non-small Cell Lung Cancer

open access: yesChinese Journal of Lung Cancer, 2010
Background and objective RECIST (Response Evaluation Criteria in Solid Tumors) criteria could not be used to detect viable tumor tissue and is not an accurate tool for evaluation of objective response (OR) in non-small cell lung cancer (NSCLC) patients ...
Chong'an XU   +3 more
doaj  

Development and Validation of a Predictive Nomogram for Diagnosing Colorectal Cancer Based on Immune‐Nutritional Score

open access: yesCancer Medicine, Volume 15, Issue 6, June 2026.
ABSTRACT Background Early diagnosis of colorectal cancer (CRC) can significantly improve prognosis, but currently there is a lack of simple and effective screening methods in clinical practice. Methods This single‐center retrospective study included patients with CRC and benign colorectal polyps (BCP) diagnosed at our hospital between December 2020 and
Xiaofan Liu   +8 more
wiley   +1 more source

Clinical characteristics, treatment response, and survival outcomes in melanoma patients with cavity carcinomatosis: A retrospective analysis

open access: yesInternational Journal of Cancer, Volume 158, Issue 9, Page 2418-2428, 1 May 2026.
What's new? Cavity carcinomatosis, a late manifestation of cancer, fuels tumor formation throughout a large area, most commonly the peritoneal and pleural cavities. The condition also can lead to resistance to otherwise effective treatment strategies.
Zhongqiao Lin   +6 more
wiley   +1 more source

Association of Serum Levels of Fibroblast Growth Factor Receptor-3 and Cytokeratin-19 with Invasive and Non-invasive Bladder Cancer in a Sample of the Iraqi Population

open access: yesThe Iraqi Journal of Medical Sciences
Background    Bladder cancer (BC) is the tenth most prevalent cancer worldwide. The fibroblast growth factor receptor 3 (FGFR3) controls essential signaling pathways that govern several cellular processes, including proliferation and migration ...
Hasan N. Smeasm   +2 more
doaj   +1 more source

Clinical Significance of Serum Assay of CYFRA21-1 in Primary Lung Cancer.

open access: yesHaigan, 1995
原発性肺癌における新しい腫瘍マーカーであるサイトケラチン19フラグメント (CYFRA21-1) の臨床的意義を検討するため原発性肺癌患者52例と他の肺疾患患者38例, 健常者22例について血清CYFRA21-1を測定し, 他の腫瘍マ-カー (CEA, SCC, NSE) と比較検討した.cut-off値を3.5ng/mlとすると原発性肺癌における陽性率は65%, 他の肺疾患における偽陽性率は8%であった.組織型別では, 扁平上皮癌で88.9%と最も高い陽性率を示し, 腺癌でも61.5%の陽性率を示した.免疫組織学的検討では扁平上皮癌において細胞質内で均一に強陽性に染色された.臨床病期別検討では, 1期50%, II期50%, IIIA期40%, IIIB期71%, IV期72 ...
Horiguchi, Takahiko   +9 more
openaire   +2 more sources

The Diagnostic and Prognostic Value of the Combination of Tumor M2-Pyruvate Kinase, Carcinoembryonic Antigen, and Cytokeratin 19 Fragment in Non-Small Cell Lung Cancer

open access: yesTechnology in Cancer Research & Treatment
Objective: Finding biomarkers related to non-small cell lung cancer (NSCLC) is helpful for the diagnosis and precise treatment of lung cancer. The relationship between serum tumor M2-pyruvate kinase (TuM2-PK), carcinoembryonic antigen (CEA), and ...
Li Li MD   +5 more
doaj   +1 more source

Cytopathologic Features of Metastatic Malignant Mesothelioma With SMARCB1 (INI‐1) Deficient Diagnosed by Ultrasound‐Guided Fine‐Needle Aspiration: A Case Report

open access: yesDiagnostic Cytopathology, Volume 54, Issue 4, Page E87-E92, April 2026.
ABSTRACT Malignant mesothelioma (MM) is a rare yet aggressive neoplasm that arises from mesothelial cells lining the thoracic and abdominal cavities, the pericardium, and the tunica testis. Characterized by rapid progression, high invasiveness, and a poor prognosis, MM poses significant clinical challenges. SMARCB1, also referred to as INI‐1, hSNF5, or
Jun Yang   +4 more
wiley   +1 more source

Case of Gastric Signet Ring Cell Carcinoma With Pulmonary Lymphangitic Carcinomatosis as the Initial Manifestation Diagnosed by Computed Tomography‐Guided Percutaneous Lung Biopsy

open access: yesRespirology Case Reports, Volume 14, Issue 4, April 2026.
We report a case of gastric signet ring cell carcinoma with pulmonary lymphangitic carcinomatosis as the initial manifestation without gastrointestinal symptoms confirmed by CT‐guided percutaneous lung biopsy, with the aim of providing insights into diagnostic methods and differential diagnosis of similar cases.
Ping Li   +3 more
wiley   +1 more source

Acute Intestinal Obstruction Caused by Dual‐Component Metastasis From Combined Small Cell Lung Cancer: A Rare Case and Literature Review

open access: yesClinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT This case report describes a 75‐year‐old male patient who was admitted due to acute intestinal obstruction. The patient had a history of small cell lung cancer. Emergency surgery pathology confirmed the presence of primary composite small cell lung cancer with rare independent dual component metastasis: The colonic lesion was metastatic poorly
Wei Jiang, Xiaohui Zhou, Xizhang Zhu
wiley   +1 more source

Serum CYFRA21–1 and SCC-Ag levels in women during pregnancy and their diagnostic value for cervical cancer

open access: yesCancer Treatment and Research Communications
Objectives: The incidence of cervical cancer increases every year during pregnancy. Cervical cytology in pregnant women has a unique morphology and liquid-based cytology methods are prone to cause false positives. The aim of this study was to investigate
Qianlan Zhang   +6 more
doaj   +1 more source

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