Results 1 to 10 of about 719 (182)

Gut mucosal immune responses and protective efficacy of oral yeast Cyprinid herpesvirus 2 (CyHV-2) vaccine in Carassius auratus gibelio [PDF]

Frontiers in Immunology, 2022
Cyprinid herpesvirus 2 (CyHV-2) causes herpesviral hematopoietic necrosis (HVHN) disease outbreaks in farmed Cyprinid fish, which leads to serious economic losses worldwide.
Yong Zhou, Zhen Xu
exaly   +9 more sources

Susceptibility of Goldfish to Cyprinid Herpesvirus 2 (CyHV-2) SH01 Isolated from Cultured Crucian Carp [PDF]

Viruses, 2021
Cyprinid herpesvirus 2 (CyHV-2), a member of the Alloherpesviridae family belonging to the genus Cyprinivirus, is a fatal contagious aquatic pathogen that affects goldfish (Carassius auratus) and crucian carp (Carassius carassius).
Liqun Lu, Hao Wang
exaly   +7 more sources

The identification of viral ribonucleotide reductase encoded by ORF23 and ORF141 genes and effect on CyHV-2 replication [PDF]

Frontiers in Microbiology, 2023
IntroductionRibonucleotide reductase (RR) is essential for the replication of the double-stranded DNA virus CyHV-2 due to its ability to catalyze the conversion of ribonucleotides to deoxyribonucleotides, and is a potential target for the development of ...
Wenjie Cheng, Wenjie Cheng, Wenjie Cheng, Qikang Chen, Qikang Chen, Qikang Chen, Yilin Ren, Yilin Ren, Yilin Ren, Ye Zhang, Ye Zhang, Ye Zhang, Ye Zhang, Liqun Lu, Liqun Lu, Liqun Lu, Liqun Lu, Lang Gui, Lang Gui, Lang Gui, Lang Gui, Dan Xu, Dan Xu, Dan Xu, Dan Xu   +24 more
doaj   +4 more sources

Screening and identification of cyprinid herpesvirus 2 (CyHV-2) ORF55-interacting proteins by phage display [PDF]

Virology Journal, 2023
Background Cyprinid herpesvirus 2 (CyHV-2) is a pathogenic fish virus belonging to family Alloherpesviridae. The CyHV-2 gene encoding thymidine kinase (TK) is an important virulence-associated factor.
Min Qian, Simin Xiao, Yapeng Yang, Fei Yu, Jinxuan Wen, Liqun Lu, Hao Wang   +6 more
doaj   +4 more sources

Complete Genome and Molecular Characterization of a New Cyprinid Herpesvirus 2 (CyHV-2) SH-01 Strain Isolated from Cultured Crucian Carp [PDF]

Viruses, 2022
Cyprinid herpesvirus 2 (CyHV-2) is a causative factor of herpesviral hematopoietic necrosis (HVHN) in farmed crucian carp (Carassius carassius) and goldfish (Carassius auratus). In this study, we analyzed the genomic characteristics of a new strain, CyHV-
Jia Yang, Jinxuan Wen, Simin Xiao, Chang Wei, Fei Yu, Patarida Roengjit, Liqun Lu, Hao Wang   +7 more
doaj   +4 more sources

Alterations of Plasma Biochemical and Immunological Parameters and Spatiotemporal Expression of TLR2 and TLR9 in Gibel Carp (Carassius auratus gibelio) after CyHV-2 Infection [PDF]

Pathogens, 2023
Cyprinid herpesvirus II (CyHV-2), a highly contagious pathogen of gibel carp (Carassius auratus gibelio), causes herpesviral hematopoietic necrosis disease (HVHND) and enormous financial losses.
Jinwei Gao, Yiwen Hu, Min Xie, Hao Wu, Jiayu Wu, Bingwen Xi, Rui Song, Dongsheng Ou   +7 more
doaj   +4 more sources

Establishment and characterization of fantail goldfish fin (FtGF) cell line from goldfish, Carassius auratus for in vitro propagation of Cyprinid herpes virus-2 (CyHV-2) [PDF]

PeerJ, 2020
Background Herpesviral hematopoietic necrosis disease, caused by cyprinid herpesvirus-2 (CyHV-2), is responsible for massive mortalities in the aquaculture of goldfish, Carassius auratus.
Arathi Dharmaratnam, Raj Kumar, Basheer Saidmuhammed Valaparambil, Neeraj Sood, Pravata Kumar Pradhan, Sweta Das, T. Raja Swaminathan   +6 more
doaj   +5 more sources

Incidence of Carassius auratus Gibelio Gill Hemorrhagic Disease Caused by CyHV-2 Infection Can Be Reduced by Vaccination with Polyhedra Incorporating Antigens [PDF]

Vaccines, 2021
Encapsulation of antigens within protein microcrystals (polyhedra) is a promising approach for the stable delivery of vaccines. In this study, a vaccine was encapsulated into polyhedra against cyprinid herpesvirus II (CyHV-2).
Tingting Zhang, Yuchao Gu, Xiaohan Liu, Rui Yuan, Yang Zhou, Yaping Dai, Ping Fang, Yongjie Feng, Guangli Cao, Hui Chen, Renyu Xue, Xiaolong Hu, Chengliang Gong   +12 more
doaj   +5 more sources

The Combination of Molecular Adjuvant CCL35.2 and DNA Vaccine Significantly Enhances the Immune Protection of Carassius auratus gibelio against CyHV-2 Infection [PDF]

Vaccines, 2020
Cyprinid herpesvirus 2 (CyHV-2) infection results in huge economic losses in gibel carp (Carassius auratus gibelio) industry. In this study, we first constructed recombinant plasmids pcORF25 and pcCCL35.2 as DNA vaccine and molecular adjuvant against ...
Xingchen Huo, Chengjian Fan, Taoshan Ai, Jianguo Su   +3 more
doaj   +5 more sources

Immune gene expression in cyprinid herpesvirus-2 (CyHV-2)-sensitized peripheral blood leukocytes (PBLs) co-cultured with CyHV-2-infected goldfish fin cell line. [PDF]

Aquac Int, 2021
Goldfish is one of the preferred ornamental fish which is highly susceptible to cyprinid herpesvirus-2 (CyHV-2) infection. The present study aimed to analyse immune gene expression in a co-culture of CyHV-2-sensitized goldfish peripheral blood leukocytes (PBLs) with CyHV-2-infected fantail goldfish fin cell lines (FtGF).
Das S, Dharmaratnam A, Ravi C, Kumar R, Swaminathan TR.   +4 more
europepmc   +4 more sources