Results 11 to 20 of about 24,424,343 (169)

Gut mucosal immune responses and protective efficacy of oral yeast Cyprinid herpesvirus 2 (CyHV-2) vaccine in Carassius auratus gibelio [PDF]

Frontiers in Immunology, 2022
Cyprinid herpesvirus 2 (CyHV-2) causes herpesviral hematopoietic necrosis (HVHN) disease outbreaks in farmed Cyprinid fish, which leads to serious economic losses worldwide.
Zhao-Ran Dong, Qing-Jiang Mu, Wei-Guang Kong, Da-Cheng Qin, Yong Zhou, Xin-You Wang, Gao-Feng Cheng, Yang-Zhi Luo, Tao-Shan Ai, Zhen Xu, Zhen Xu   +10 more
doaj   +5 more sources

Incidence of Carassius auratus Gibelio Gill Hemorrhagic Disease Caused by CyHV-2 Infection Can Be Reduced by Vaccination with Polyhedra Incorporating Antigens [PDF]

Vaccines, 2021
Encapsulation of antigens within protein microcrystals (polyhedra) is a promising approach for the stable delivery of vaccines. In this study, a vaccine was encapsulated into polyhedra against cyprinid herpesvirus II (CyHV-2).
Tingting Zhang, Yuchao Gu, Xiaohan Liu, Rui Yuan, Yang Zhou, Yaping Dai, Ping Fang, Yongjie Feng, Guangli Cao, Hui Chen, Renyu Xue, Xiaolong Hu, Chengliang Gong   +12 more
doaj   +5 more sources

Analysis of MHC class II-bound CyHV-2 peptides in Carassius gibelio using mass spectrometry [PDF]

Journal of Virology
Class II major histocompatibility complexes (MHC-II) are a highly polymorphic and multigenic family of molecules that present exogenous peptides to CD4+ helper T cells, thereby activating the host adaptive immune system.
Chen Xu, Fangxing Yu, Jiajia Ye, Mingyang Xue, Zhenyu Huang, Nan Jiang, Yan Meng, Yuding Fan, Weiguang Kong, Ya Zheng, Yong Zhou   +10 more
doaj   +4 more sources

Emergence and persistence of Cyvirus cyprinidallo 2 (CyHV-2) in Prussian carp in Serbian lakes

Aquaculture
Between 2018 and 2021, significant die-offs of Prussian carp (Carassius gibelio) occurred in five lakes in eastern, central and northern Serbia. In all cases, Cyvirus cyprinidallo 2, formerly named Cyprinid herpesvirus 2 (CyHV-2) infection was suspected, based on initial diagnostic observations.
Ksenija Nesic, Vladimir Radosavljevic, Jelena Maksimovic Zoric   +2 more
exaly   +4 more sources

Immune gene expression in cyprinid herpesvirus-2 (CyHV-2)–sensitized peripheral blood leukocytes (PBLs) co-cultured with CyHV-2-infected goldfish fin cell line [PDF]

Aquaculture International, 2021
Goldfish is one of the preferred ornamental fish which is highly susceptible to cyprinid herpesvirus-2 (CyHV-2) infection. The present study aimed to analyse immune gene expression in a co-culture of CyHV-2-sensitized goldfish peripheral blood leukocytes (PBLs) with CyHV-2-infected fantail goldfish fin cell lines (FtGF).
Sweta Das, Arathi Dharmaratnam, Charan Ravi, Raj Kumar, Thangaraj Raja Swaminathan   +4 more
openaire   +3 more sources

Cyprinid herpesvirus‐2 (CyHV‐2): a comprehensive review [PDF]

Reviews in Aquaculture, 2020
AbstractCyprinid herpesvirus‐2 (CyHV‐2) is a linear double‐stranded DNA virus in the genus Cyprinivirus of family Alloherpesviridae. The virus is known to be highly pathogenic to ornamental goldfish (Carassius auratus), crucian carp (C. carassius) and Gibel carp (C. auratus gibelio), and also to the hybrids of goldfish and other carps.
Raja Swaminathan Thangaraj, Sundar Raj Nithianantham, Arathi Dharmaratnam, Raj Kumar, Pravata Kumar Pradhan, Sumithra Thangalazhy Gopakumar, Neeraj Sood   +6 more
openaire   +4 more sources

Establishment and characterization of fantail goldfish fin (FtGF) cell line from goldfish, Carassius auratus for in vitro propagation of Cyprinid herpes virus-2 (CyHV-2) [PDF]

PeerJ, 2020
Background Herpesviral hematopoietic necrosis disease, caused by cyprinid herpesvirus-2 (CyHV-2), is responsible for massive mortalities in the aquaculture of goldfish, Carassius auratus.
Arathi Dharmaratnam, Raj Kumar, Basheer Saidmuhammed Valaparambil, Neeraj Sood, Pravata Kumar Pradhan, Sweta Das, T. Raja Swaminathan   +6 more
doaj   +3 more sources

Generation and Characterization of ORF55/ORF57-Deleted Recombinant Cyprinid herpesvirus 2 Mutants with Chimeric Capsid Protein Gene of Grouper Nervous Necrosis Virus [PDF]

Vaccines, 2023
Cyprinid herpesvirus 2 (CyHV-2) is a pathogen that causes significant losses to the global aquaculture industry due to mass mortality in crucian carp and goldfish. This study demonstrates that the ORF55/ORF57 deletion mutants CyHV-2-Δ55-CP and CyHV-2-Δ57-
Zizhao Feng, Wenjie Cheng, Mingyang Ma, Chenwei Yu, Ye Zhang, Liqun Lu, Hao Wang, Lang Gui, Dan Xu, Chuanfu Dong   +9 more
doaj   +2 more sources

Evaluation of Cyprinid Herpesvirus 2 Latency and Reactivation in Carassius gibel

Microorganisms, 2020
Cyprinid herpesvirus 2 (CyHV-2, species Cyprinid herpesvirus 2) causes severe mortality in ornamental goldfish, crucian carp (Carassius auratus), and gibel carp (Carassius gibelio).
Wenjun Chai, Lin Qi, Yujun Zhang, Mingming Hong, Ling Jin, Lijuan Li, Junfa Yuan   +6 more
doaj   +2 more sources

CRISPR‐Enhanced RAA‐SHERLOCK Assay for Point‐of‐Care Detection of Cyprinid Herpesvirus‐3: Development, Validation and Clinical Application [PDF]

Journal of Fish Diseases, Volume 49, Issue 4, April 2026.
ABSTRACT Koi herpesvirus disease (KHVD), caused by Cyprinid herpesvirus‐3 (CyHV‐3), poses a significant threat to global aquaculture due to its high mortality rates and economic impact. Current diagnostic methods, such as PCR, are limited by equipment dependency and procedural complexity, hindering point‐of‐care (POC) applications.
Hatem Soliman, Naveed Akram, Mona Saleh
wiley   +2 more sources