Results 191 to 200 of about 3,601 (247)

Electrochemical Investigation of DNA Interactions with Cyanobacterial Toxins: Cylindrospermopsin and Saxitoxin

ChemistrySelect
Anthropogenic eutrophication threatens freshwater sources used for agricultural irrigation and increases the occurrence risk of cyanotoxins, such as cylindrospermopsin (CYN) and saxitoxin (STX).
Ece Kesici‐Meco, Mete Yilmaz, Ece Unur‐Yilmaz   +2 more
semanticscholar   +1 more source

Genotoxicity investigation of a cyanobacterial toxin, cylindrospermopsin

Toxicon, 2002
Cylindrospermopsin (CYN), a potent cyanobacterial hepatotoxin produced by Cylindrospermopsis raciborskii and other cyanobacteria, is regularly found in water supplies in many parts of the world, and has been associated with the intoxication of humans and livestock.
Shen, X. Y., Lam, P. K. S., Shaw, G. R., Wickramasinghe, W.   +3 more
openaire   +5 more sources

Evaluation of harmful impact of low concentration cylindrospermopsin through zebrafish behavioral endpoints under multiple life stages.

Journal of Hazardous Materials
Cylindrospermopsin (CYN) is a toxic substance produced by cyanobacteria. It has attracted much attention due to its widespread global distribution, bioaccumulation and multi organ toxicity.
Minghui Fu, Yi-Ning Zhang, L. Luo, Ming-Lu Wu, Liyan Teng, Jiandong Mu, Guohua Xiao, Yan-Yang Xu, Jing Qiu, Tingting Chai, Yong-Zhong Qian, Guijie Hao, Xiyan Mu   +12 more
semanticscholar   +1 more source

Cylindrospermopsin exposure promotes redox unbalance and tissue damage in the liver of Poecilia reticulata, a neotropical fish species

Journal of Toxicology and Environmental Health, Part A, 2023
There is a growing concern regarding the adverse risks exposure to cylindrospermopsin (CYN) might exert on animals and humans. However, data regarding the toxicity of this cyanotoxin to neotropical fish species are scarce. Using the fish species Poecilia
S. M. T. de Sabóia-Morais, João Marcos de Lima Faria, Jéssica Custódio da Silva Rabelo, A. L. Hanusch, L. A. Mesquita, Raquel de Andrade Silva, J. D. de Oliveira, L. W. O. de Jesus   +7 more
semanticscholar   +1 more source

First occurrence of cylindrospermopsin in freshwater in France

Environmental Toxicology, 2008
AbstractEleven waterbodies in Western France dominated by cyanobacteria of the genera Aphanizomenon and Anabaena were analyzed in September 2006 for microcystins (MC) and cylindrospermopsin (CYN). CYN was detected for the first time in France in four of them in the presence of Aphanizomenon flos‐aquae and in the presence of Anabaena planctonica in the ...
Brient, Luc, Lengronne, Marion, Bormans, Myriam, Fastner, Jutta   +3 more
openaire   +4 more sources

Cytotoxicity Screening for the Cyanobacterial Toxin Cylindrospermopsin

Journal of Toxicology and Environmental Health, Part A, 2009
The cell lines C3A, HepG2, NCI-87, HCT-8, HuTu-80, Caco-2, and Vero were screened for sensitivity to the cyanobacterial toxin cylindrospermopsin (CYN), with the aim of determining the most sensitive cells to be used in cytotoxicity tests. Cell lines were chosen to be representative of the organs targeted by the toxin; liver, kidney, intestine, and were
Froscio, S., Fanok, S., Humpage, A.
openaire   +3 more sources

Biosynthesis of Cylindrospermopsin in Cyanobacteria: Characterization of CyrJ the Sulfotransferase

Journal of Natural Products, 2021
7-Deoxy-desulfo-cylindrospermopsin was purified at small-scale from the supernatant of a culture of the cyanobacterium Oscillatoria sp. PCC 10702. This metabolite was obtained in a pure form using a three-step chromatographic procedure, and its identity was confirmed by liquid chromatography-tandem mass spectrometry (LC-MS/MS).
Annick Méjean, Olivier Ploux
openaire   +2 more sources

Single and mixture effect of cyanobacterial metabolites, cylindrospermopsin, anabaenopeptin-A, microginin-FR1 and aeruginosin 98-A, on behaviour, food uptake, oxygen consumption and muscular F-actin degradation of Thamnocephalus platyurus.

Environmental Toxicology and Pharmacology
This study showed that single cyanobacterial metabolites had various effects on the tested parameters. Among them, only cylindrospermopsin was lethal to the animals; cylindrospermopsin was also the most potent inhibitor of the remaining parameters ...
M. Adamczuk, A. Bownik, B. Pawlik-Skowrońska   +2 more
semanticscholar   +1 more source

Interlaboratory comparison trial on cylindrospermopsin measurement

Analytical Biochemistry, 2004
The hepatotoxin cylindrospermopsin (CYN) is a potent inhibitor of protein synthesis in mammalian cells. It is produced by freshwater cyanobacterial blooms in countries such as Australia, the United States, Israel, Thailand, and Brazil. An interlaboratory comparison was organized as a first step to evaluate the measurement of CYN in lyophilized ...
Andrea, Törökné, Maria, Asztalos, Maria, Bánkiné, Heike, Bickel, Georg, Borbély, Shmuel, Carmeli, Geoffrey A, Codd, Jutta, Fastner, Qiong, Huang, Andrew, Humpage, James S, Metcalf, Erzsebet, Rábai, Assaf, Sukenik, Gyula, Surányi, Gabor, Vasas, Viktor, Weiszfeiler   +15 more
openaire   +2 more sources

Chronic cylindrospermopsin exposure impairs oocyte growth and maturation by stress-induced endocrine disruption and immune activation of NF-κB/TNF-α pathway in female zebrafish.

Comparative biochemistry and physiology. Toxicology & pharmacology : CBP
Cyanotoxins are one of the major threats to aquatic ecosystems due to their diverse toxic effects on aquatic organisms. Cylindrospermopsin is a globally reported freshwater cyanotoxin that exhibits hepatotoxic, cytotoxic, immunotoxic, and neurotoxic ...
Chayan Biswas, Madhuchhanda Adhikari, K. Pramanick   +2 more
semanticscholar   +1 more source