Results 101 to 110 of about 13,799 (198)

Altered expression of ECM proteins in Cyp1b1-/- LSEC.

open access: yes, 2018
Western blot analysis of ECM proteins in the conditioned medium (CM) and cell lysates from LSEC was performed. (A) The levels of SPARC, Tenascin-C, TSP2, and Osteopontin were below the level of detection.
Juliana Falero-Perez (5905103)   +5 more
core   +1 more source

Activation of the Wnt/β-catenin/CYP1B1 pathway alleviates oxidative stress and protects the blood-brain barrier under cerebral ischemia/reperfusion conditions

open access: yesNeural Regeneration Research
Accumulating evidence suggests that oxidative stress and the Wnt/β-catenin pathway participate in stroke-induced disruption of the blood-brain barrier. However, the potential links between them following ischemic stroke remain largely unknown.
Xingyong Chen   +6 more
doaj   +1 more source

Implications of CYP1B1 in the treatment and prognosis of breast cancer

open access: yesBeni-Suef University Journal of Basic and Applied Sciences
Background Cytochrome P450 1B1 (CYP1B1) enzyme plays an important metabolic role, especially in the metabolism of xenobiotics, endogenous substances, and procarcinogens. It may be involved in tumor initiation and progression.
Maria Carolina Stipp   +4 more
doaj   +1 more source

Loss of fenestrations and decreased VEGF production in Cyp1b1-/- LSEC.

open access: yes, 2018
(A) Cyp1b1+/+ and Cyp1b1-/- LSEC of early passage were examined under the electron microscopy (×17600) for fenestrations. Clusters of fenestrations were found aligned in the peripheries of Cyp1b1+/+ LSEC with the expected size of 50–200 nm in diameter ...
Juliana Falero-Perez (5905103)   +5 more
core   +1 more source

Identification and validation of the important role of tryptophan-related gene CYP1B1 in the development and progression of sepsis.

open access: yesPLoS ONE
BackgroundTryptophan metabolism is involved in the progression and immune response of multiple diseases. However, the function of tryptophan metabolism in the immune characteristics of sepsis still needs to be elucidated.MethodsWe collected the datasets ...
Li-Hong Chen   +4 more
doaj   +1 more source

Characterization of the Mouse Cyp1B1 Gene [PDF]

open access: yesJournal of Biological Chemistry, 1998
Leying Zhang   +3 more
openaire   +1 more source

Mutation Screening of the CYP1B1 Gene Reveals Novel and Recurrent Pathogenic Variants in Pakistani Primary Congenital Glaucoma Patients

open access: yesJLUMHS
OBJECTIVE: To identify the pathogenic alleles in primary congenital glaucoma patients for early cure of the disease   METHODOLOGY:  A cross-sectional descriptive study was carried out after approval from the ethical committee of SIOVS from December 2022
Waqas Ali Surhio   +4 more
doaj   +1 more source

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