Results 81 to 90 of about 13,799 (198)
Cell Death and Disease, 2022 Zinc finger proteins (ZNFs) have been demonstrated to participate extensively in breast cancer progression by functioning as transcription factors, but there are still a variety of ZNFs whose biological mechanisms remain unknown.
Ting Lei +12 more
doaj +1 more source
Ischemic Stroke and Traumatic Brain Injury: Epidemiology, Molecular Pathways, and Emerging Therapies
MedComm, Volume 7, Issue 10, October 2026.Schematic overview of secondary brain injury after ischemic stroke and traumatic brain injury. Both conditions trigger endothelial cell dysfunction, pericyte contraction, and upregulated AQP4 expression in astrocytic end‐feet, leading to blood–brain barrier disruption.
Mengzhao Feng +7 more
wiley +1 more source
Spontaneously arrested primary congenital glaucoma
Oman Journal of OphthalmologyThis case report explores a unique instance of primary congenital glaucoma (PCG), where the expected progression was unexpectedly halted without intervention.
Priyasha Goel +3 more
doaj +1 more source
Allergy, Volume 81, Issue 10, Page 3554-3567, October 2026.We exposed human nasal epithelial tissues to pollen from grasses grown under different climate treatments (temperature and CO2). Pollen weakened epithelial tight junctions and altered cytokine‐related gene expression, with similar protein‐level effects.
Tarleena Tossavainen +5 more
wiley +1 more source
Altered expression of integrins in Cyp1b1-/- LSEC.
, 2018 The expression of various integrins in LSEC was determined by FACS analysis as detailed in Methods. Cyp1b1-/- LSEC expressed increased levels of α3, α5β1, and αvβ3.
Juliana Falero-Perez (5905103) +5 more
core +1 more source
Expression profiles of CYP1A1 and CYP1B1 enzymes in Non-small Cell Lung Cancer of Turkish Patients
Сибирский онкологический журналBackground. The cytochrome P450 enzymes CYP1A1 and CYP1B1 are involved in the metabolism of carcinogens and have been linked to various cancers, including lung cancer, primarily through their overexpression in tumor tissues. Aim of study.
H. Bayram +7 more
doaj +1 more source
Chemical Biology &Drug Design, Volume 108, Issue 4, October 2026.Single‐cell and multi‐omics analyses identified THBS1+ macrophages as a terminally differentiated, hypoxia‐adaptive population driving coronary atherosclerosis through THBS1‐CD36 signaling with lymphatic endothelial cells. Targeting CD36 with SMS121 and leveraging a THBS1+ macrophage gene signature enabled therapeutic prediction and accurate risk ...
Jianpeng Li +4 more
wiley +1 more source
CYP1B1 enhances cell proliferation.
, 2016 (A) Relative cell viability determined by CCK assay subsequent to induction of CYP1B1 in MCF-7 cells following CYP1B1 overexpression. Data are representative of experiments in triplicate.
Hyoung-Seok Baek (3178263) +5 more
core +1 more source
Chemical Biology &Drug Design, Volume 108, Issue 4, October 2026.The long non‐coding RNA MALAT1 acts as a catalyst for non‐small cell lung cancer (NSCLC) progression by targeting METTL3, an interaction that precipitates the downregulation of the tumor suppressor INPP5B. ABSTRACT m6A modification regulates the functions of long non‐coding RNAs (lncRNAs) through diverse mechanisms.
Shuhong Tian +5 more
wiley +1 more source
CYP1B1-mediated Pathobiology of Primary Congenital Glaucoma
Journal of Current Glaucoma Practice, 2015 CYP1B1 is a dioxin-inducible enzyme belonging to the cytochrome P450 superfamily. It has been observed to be important in a variety of developmental processes including in utero development of ocular structures. Owing to its role in the developmental biology of eye, its dysfunction can lead to ocular developmental defects.
Faiq, Muneeb A +3 more
openaire +2 more sources