Results 151 to 160 of about 13,799 (198)
IBD risk locus rs1077773 enhances aryl hydrocarbon receptor activity and modulates immune cell function in vitro. [PDF]
Inflamm ResKing AC +4 more
europepmc +1 more source
Detection and Potency Classification of Pre- and Pro-Haptens Using the SENS-IS Assay: The Role of Metabolically Competent Reconstructed Skin. [PDF]
ToxicsCottrez F +5 more
europepmc +1 more source
Long-term health outcomes and comorbidities in cytochrome P450 oxidoreductase (POR) deficiency: a scoping review of evidence and knowledge gaps. [PDF]
Endocr ConnectKouri C, Thirukkumar A, Flück CE.
europepmc +1 more source
Immunohistochemical Localization of Cytochrome P450 CYP1B1 in Breast Cancer With Monoclonal Antibodies Specific for CYP1B1 [PDF]
Journal of Histochemistry and Cytochemistry, 1999 Cytochrome P450 CYP1B1 is a recently identified member of the CYP1 P450 family. We have shown that this P450 displays increased expression in several types of human cancer, indicating that CYP1B1 is a potential tumor biomarker.
Morag C E McFadyen +2 more
exaly +4 more sources
Some of the next articles are maybe not open access.
Related searches:
Related searches:
Quinazoline Derivatives as Selective CYP1B1 Inhibitors
European Journal of Medicinal Chemistry, 2017CYP1B1 is implicated to have a role in the development of breast, ovarian, renal, skin and lung carcinomas. It has been suggested that identification of potent and specific CYP1B1 inhibitors can lead to a novel treatment of cancer. Flavonoids have a compact rigid skeleton which fit precisely within the binding cavity of CYP1B1.
Sandip B Bharate +2 more
exaly +3 more sources
New Perspectives of CYP1B1 Inhibitors in the Light of Molecular Studies
Processes, 2021 Human cytochrome P450 1B1 (CYP1B1) is an extrahepatic heme-containing monooxygenase. CYP1B1 contributes to the oxidative metabolism of xenobiotics, drugs, and endogenous substrates like melatonin, fatty acids, steroid hormones, and retinoids, which are ...
Zbigniew Dutkiewicz, Renata Mikstacka
exaly +2 more sources
European Journal of Epidemiology, 2010
Cytochrome P450 1B1 (CYP1B1) is involved in the activation of a broad spectrum of procarcinogens. An association of the Cyp1B1 Leu432Val polymorphism with cancer as well as an impact on the enzyme activity has been described. To study gene-environmental interactions we investigated the quantitative Cyp1B1 mRNA expression in smokers (N = 102) and non ...
Joachim Schneider
exaly +3 more sources
Cytochrome P450 1B1 (CYP1B1) is involved in the activation of a broad spectrum of procarcinogens. An association of the Cyp1B1 Leu432Val polymorphism with cancer as well as an impact on the enzyme activity has been described. To study gene-environmental interactions we investigated the quantitative Cyp1B1 mRNA expression in smokers (N = 102) and non ...
Joachim Schneider
exaly +3 more sources
Cytochrome P450 CYP1B1 Activity in Renal Cell Carcinoma [PDF]
British Journal of Cancer, 2004 Renal cell carcinoma (RCC) is the most common malignancy of the kidney and has a poor prognosis due to its late presentation and resistance to current anticancer drugs.
Morag C E McFadyen +2 more
exaly +2 more sources
Annual Review of Pharmacology and Toxicology, 2008
Glaucoma is a leading cause of blindness, estimated to affect 60 million people by 2010, and represents a heterogeneous group of neurodegenerative disease. The two major types of glaucoma include primary open-angle glaucoma (POAG) and primary congenital glaucoma (PCG).
Vasilis, Vasiliou, Frank J, Gonzalez
openaire +2 more sources
Glaucoma is a leading cause of blindness, estimated to affect 60 million people by 2010, and represents a heterogeneous group of neurodegenerative disease. The two major types of glaucoma include primary open-angle glaucoma (POAG) and primary congenital glaucoma (PCG).
Vasilis, Vasiliou, Frank J, Gonzalez
openaire +2 more sources