Case Report: Severe SIADH and QTc prolongation induced by escitalopram-quetiapine interaction in a CYP2C19 intermediate metabolizer at therapeutic doses. [PDF]
Jiang Z +6 more
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Self-Reported Pharmacogenetic Medication Use in the Our Future Health Cohort. [PDF]
Dixon P +4 more
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An Exploratory, Retrospective Study of the CYPRI Score for Pharmacogenetic Testing Among Mental Health Patients. [PDF]
Comtesse SM +3 more
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Exploring the roles of cytochrome P450 enzymes and their inhibitors in cancers and non-neoplastic human diseases. [PDF]
Lee H, Kwon YJ, Chun YJ.
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Association of Clopidogrel Genetic Polymorphism With Efficacy and Safety for Ischemic Stroke or Transient Ischemic Attack: A Systematic Review and Updated Meta-Analysis. [PDF]
Park H +8 more
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Unraveling enantioselective metabolism: Human cytochrome P450s in arachidonic acid biotransformation. [PDF]
Isse FA, El-Sherbeni AA, El-Kadi AOS.
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Revisiting the Proton Pump Inhibitor-Clopidogrel Conundrum: Do PPIs Truly Worsen Cardiovascular Outcomes? [PDF]
Bavishi C, Hirai T.
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Confounding Effect of Hepatic Carboxylesterase 1 (CES1) Variability on Clopidogrel Oxidation. [PDF]
Subash S +8 more
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Correction to "Genotype-Specific Safety and Pharmacokinetics of Cannabidiol in Healthy Volunteers". [PDF]
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CYP2C19 gene polymorphism in Ningxia
Pharmacological Reports, 2023Poor metabolizer (PM) status of CYP2C19 can be a predisposing factor for developing gastric cancer in H. pylori-infected patients. It is unclear whether PM status of CYP2C19 can also be a potential factor for H.pylori infection in healthy people.We used high-throughput sequencing to detect single nucleotide polymorphisms (SNPs) at just three loci ...
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