Results 161 to 170 of about 45,621 (284)
CYP2C19*2 polymorphism and clopidogrel resistance [PDF]
Archivos de cardiolog�a de M�xico (English ed. Internet), 2021 Beuy, Joob, Viroj, Wiwanitkit
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Clinical Pharmacology &Therapeutics, Volume 119, Issue 1, Page 241-254, January 2026.Overview of the implemented pharmacogenomics (PGx) process in clinical routine at the Robert Bosch Hospital: from patient enrollment via the hospital information system, DNA detection using a customized TaqMan OpenArray panel and qPCR for CNV assessment, to clinical translation of genotyping results into PGx guideline‐based recommendations using a ...
Roman Tremmel +13 more
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Food Safety and Health, Volume 4, Issue 1, Page 220-232, January 2026.Vanillin showed moderate sedative and modulatory synergistic activities on diazepam in thiopental sodium‐induced sleeping mice. These effects are implicated with GABAergic intervention. ABSTRACT Insomnia is a common sleep disorder affecting approximately 10% of adults.
Salehin Sheikh +8 more
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Food Science &Nutrition, Volume 14, Issue 1, January 2026.In U87 cells, meranzin hydrate showed cytotoxicity (MIC = 50 μM) and anti‐invasion activity (IC50 = 33.12 μM) but had no inhibitory effect on colony formation. It also suppressed the cancer stem cell property of sphere formation (IC50 = 21.43 μM). In silico analysis indicated that meranzin hydrate may downregulate the protein expression of ALDH1A1 and ...
Shi‐Ying Huang +10 more
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Omega-3 Polyunsaturated Fatty Acids in Treatment of Patients with Coronary Heart Disease and Type 2 Diabetes Mellitus [PDF]
, 2012 Increased platelet aggregation is one of the major risk factors for cardiovascular events. However, recent studies have demonstrated the inhibition of platelet aggregation by omega-3 PUFAs.
Aisulu T. Mussagalieva, MD, PhD +1 more
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The Journal of Clinical Pharmacology, Volume 66, Issue 1, January 2026.Abstract Miricorilant is a novel selective glucocorticoid receptor (GR) modulator with mixed agonist/antagonist effects at the GR and modest antagonism at the mineralocorticoid receptor that is being developed for the treatment of metabolic dysfunction‐associated steatohepatitis.
Hazel J. Hunt +3 more
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Trombocita aggregáció gátló kezelés hatékonyságának genetikai és metodikai aspektusai koronária intervención átesett betegek körében [PDF]
, 2011 Coronary artery disease (CAD) is known to be a very heterogeneous disease of multifactorial origin affecting millions world-wide and being the top leading cause of death among the middle-aged population.
Rideg Orsolya
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Pharmacogenomics and Personalized Medicine, 2020 Benjamin Q Duong,1 Meghan J Arwood,2 J Kevin Hicks,3 Amber L Beitelshees,4 Francesco Franchi,5 John T Houder,2 Nita A Limdi,6 Kelsey J Cook,7,8 Aniwaa Owusu Obeng,9 Natasha Petry,10 Sony Tuteja,11 Amanda R Elsey,2 Larisa H Cavallari,2 Kristin Wiisanen2 ...
Duong BQ +13 more
doaj
A Rational Approach to Pharmacotherapy in Pregnancy
The Journal of Clinical Pharmacology, Volume 66, Issue 1, January 2026.Abstract Most pregnant individuals are exposed to at least one medication, whether prescription or over the counter, during pregnancy. Despite the ubiquity of medication use in pregnancy, there remains no standardized framework to guide clinicians in selecting the most appropriate pharmacotherapy that balances maternal needs with fetal safety. This gap
Gregory W. Kirschen +2 more
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Биомедицина, 2013 Individual variation in the response to drug therapy has been mainly attributed to the genetic polymorphism of cytochrome P 450 isoenzymes. We examined 40 patients with CHD, who received clopidogrel and 146 healthy volunteers. CYP2C19*2, CYP2C19*3, CYP2C19*17 carriage was determined by a polymerase chain reaction.
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