Results 141 to 150 of about 28,620 (235)

Influence of CYP2C19 genotypes on clopidogrel treatment

, 2020
In last years, there has been a trend that stroke and heart attack are no longer exclusively diseases of the elderly, but are quite common in younger people.
Melnik, V. A., Liudkevych, H. P., Sukhan, D. S., Orlenko, V. S., Solovei, O. S.   +4 more
core  

Linkage disequilibrium between the CYP2C19*2,*17 and CYP2C9*1 alleles and impact of VKORC1, CYP2C9, CYP2C19 gene polymorphisms and gene-gene interactions on warfarin therapy.

, 2017
Warfarin therapy is complicated by its large inter-individual and intra-individual variability. Both genetic and non-genetic factors can affect warfarin therapy.
Khalighi, Bahar, Mirabbasi, Seyedabbas, Khalighi, Koroush, MD, MS, Cheng, Gang, Wu, Yin, Fan, Wuqiang   +5 more
core   +1 more source

CYP2C19 Loss-of-Function is an Associated Risk Factor for Premature Coronary Artery Disease: A Case–Control Study

Wenhao Chen,1 Yuanliang Liu,2 Xunwei Deng,3 Bin Li,1 Hao Wang,1 Guoliang Wei,1 Kehui Chen,1 Shen Wang1 1Center for Cardiovascular Diseases, Meizhou People’s Hospital, Meizhou, People’s Republic of China; 2Department of Computer Tomography, Meizhou People’
Liu Y, Chen K, Wang S, Chen W, Li B, Wang H, Wei G, Deng X   +7 more
core  

CYP2C19 and ABCB1 gene polymorphisms are differently distributed according to ethnicity in the Brazilian general population.

, 2011
Background: Recent studies have reported the clinical importance of CYP2C19 and ABCB1 polymorphisms in an individualized approach to clopidogrel treatment.
Santos, Diogo B. G., Soares, Renata A. G., Nicolau, José Carlos, Pereira, Alexandre da Costa, Santos, Paulo Caleb Júnior de Lima, Nascimento, Raimundo Marques, Mill, José Geraldo, Coelho, George Luiz Lins Machado, Krieger, José Eduardo   +8 more
core  

Association Between CYP2C19 Genotype and P2Y12 Reaction Units in Patients Receiving Clopidogrel After Acute Ischemic Stroke: A Prospective, Observational Study. [PDF]

Pharmacotherapy
Stone RM, Smith A, Gunter S, Weko AT, Gottschalk C, Lee C, Ramsey A, Weatherspoon MP, Worrall BB.   +8 more
europepmc   +1 more source

Implementation of Rapid CYP2C19 Genotyping to Guide Antiplatelet Therapy for Secondary Prevention of Ischemic Stroke and Transient Ischemic Attack. [PDF]

Clin Pharmacol Ther
Smith DM, Ramos Ramos P, Ashena S, Barnes J, Barnett AC, Barrow VL, Beyene RA, Broussard J, Chahine J, Deogan S, Gooden RA, Dawson E, Dawson K, Goff N, Hsia AW, McAlduff J, Moriarty K, Reuter J, San Juan VP, Somani S, Syed NP, Tsang PC, Woodward A, Zaveri DJ, Zeck JC, Stemer A, Swain SM.   +26 more
europepmc   +1 more source

Association of CYP2C19 genetic polymorphisms with dyslipidemia and ischemic cerebrovascular disease in the mongolian population: A case-control study. [PDF]

Medicine (Baltimore)
Hu G, Zhang J, Shi R, Yu J, Wang S, Hu B, Bao P, Wang Y.   +7 more
europepmc   +1 more source

The pharmacokinetics and pharmacogenomics of voriconazole in pediatric Saudi patients: advancing toward precision medicine. [PDF]

Front Pharmacol
Albassam A, Alharbi A, Al Anizi H, Almuzzaini B, Alhussaini W, Aldahri A, Kurdi A, Alawdah L, Awwad S, Almuhisen S, Alsultan A, Aljeraisy M.   +11 more
europepmc   +1 more source

CYP2C19 in ACS Patients

Journal of the American College of Cardiology, 2016
Sibbing, Dirk, Gross, Lisa, Massberg, Steffen   +2 more
openaire   +1 more source

From Frequencies to Priorities: Interethnic Distribution of Pharmacogenetic Phenotypes as a Basis for Prioritizing Preemptive Testing in Russia's Multiethnic Population. [PDF]

Genes (Basel)
Mirzaev KB, Abdullaev SP, Tuchkova SN, Turaev FK, Selivanova LV, Fedorinov DS, Sychev DA.   +6 more
europepmc   +1 more source