Results 171 to 180 of about 19,211 (198)

Generation and Evaluation of a CYP2C9 Heteroactivation Pharmacophore

The Journal of Pharmacology and Experimental Therapeutics, 2003
Positive cooperativity (auto- and heteroactivation) of drug oxidation, a potential cause of drug interactions, is well established in vitro for cytochrome P450 (P450) 3A4 but to a much lesser extent for other drug-metabolizing P450 isoforms. Using a high throughput fluorescent-based CYP2C9 effector assay, we identified >30 heteroactivators from a set ...
Egnell, Ann Charlotte, Eriksson, Cecilia, Albertson, Nan, Houston, Brian, Boyer, Scott   +4 more
openaire   +2 more sources

???????????? ???????????????????????????? ?????????????????? ???????????????????????? ???????? CYP2C9 ?? ?????????????????? ??????????????????

2014
???????????????? ???????????? ???????????????????????????? ???????????????????? ?????????????????????? ?????????????????? 430?? > ?? ?? 1075?? > ?? ???????? ?????????????????? ??450 CYP2C9 ?? ?????????????? ?????????????????????? ?????????????????? ?? ?? ?????????????? ???????????????? ?????? ?????????????????? ??????????????????. ????????????????, ????
openaire   +1 more source

Functional impact of CYP2C9*5, CYP2C9*6, CYP2C9*8, and CYP2C9*11 in vivo among black Africans*1

Clinical Pharmacology & Therapeutics, 2004
openaire   +1 more source

Physiologically based pharmacokinetic (PBPK) modeling of flurbiprofen in different CYP2C9 genotypes

Archives of Pharmacal Research, 2022
Seok-Yong Lee, Chang-Ik Choi, Eui Hyun Jung   +2 more
exaly  

Effects of CYP2C9*3 and *13 alleles on the pharmacokinetics and pharmacodynamics of glipizide in healthy Korean subjects

Archives of Pharmacal Research, 2021
Jung-Woo Bae, Yun Jeong Lee, Choon-Gon Jang   +2 more
exaly  

Association of polymorphisms in the cytochrome P450 CYP2C9 with warfarin dose requirement and risk of bleeding complications

Lancet, The, 1999
Ann Daly, Guruprasad Aithal, Christopher P Day   +2 more
exaly  

Influence of CYP2C9 genotype on warfarin dose requirements—a systematic review and meta-analysis

European Journal of Clinical Pharmacology, 2008
Jonatan Lindh, Anders Rane, Rane Anders   +2 more
exaly  

Functional characterization of 32 CYP2C9 allelic variants

Pharmacogenomics Journal, 2013
Masahiro Hiratsuka, Noriyasu Hirasawa
exaly  

Comparative interaction analysis of CYP2C9, CYP2C9*2 and CYP2C9*3 proteins using molecular docking approach

2019
Yadav, Anamika, Katara, Pramod
openaire   +1 more source

Frequency of cytochrome P450 CYP2C9 variants in a Turkish population and functional relevance for phenytoin

British Journal of Clinical Pharmacology, 1999
Muradiye Nacak, Ivar Roots, C Sachse
exaly