Results 211 to 220 of about 35,596 (239)

The impact of <i>CYP2C9</i>, <i>VKORC1</i>, and <i>CYP4F2</i> polymorphisms on warfarin dose requirement in Saudi patients. [PDF]

Front Pharmacol
Jokhab S, AlRasheed MM, Bakheet D, AlMomen A, AlAboud N, Kamali F.   +5 more
europepmc   +1 more source

Evaluation of drug-drug interaction potentials between JP-1366 and celecoxib using physiologically based pharmacokinetic modeling. [PDF]

Transl Clin Pharmacol
Choi SC, Kim J, Lim HS.
europepmc   +1 more source

Analysis of CYP2C9 promotor variations and possible links to the CYP2C9 2 and CYP2C9 3 exon variants.

, 2018
Schubert, C., Cubic, I., Kirchheiner, Julia, Brockmoeller, Juergen, Roots, Ivar   +4 more
openaire   +1 more source

Pharmacological Management of Oral and Esophageal Candidiasis: A Clinical Pharmacotherapy Perspective. [PDF]

J Clin Med
Hirai T, Nashi M.
europepmc   +1 more source

Distinct Interactions of Cannabinol and Its Cytochrome P450-Generated Metabolites with Receptors and Sensory Neurons. [PDF]

J Med Chem
Kundu D, Franchini L, Hasdemir HS, Lloyd E, Maturano J, Rabl K, Denissiouk AN, Schumacher M, Sarlah D, Hellman J, Tajkhorshid E, Orlandi C, Das A.   +12 more
europepmc   +1 more source

Investigation of the <i>ABCB1</i> Gene Polymorphism and Food Effects on the Avatrombopag Pharmacokinetics in Chinese Individuals: A Population Pharmacokinetic/Pharmacodynamic Analysis. [PDF]

Pharmaceuticals (Basel)
Liu X, Chen L, Ju G, Li C, Liu B, Fei Y, Wang X, Gao Y, He Q, Zhu X, Ouyang D.   +10 more
europepmc   +1 more source

Factors affecting CYP2C9-mediated metabolism

, 2019
openaire   +2 more sources

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CATALYTIC ROLES OF CYP2C9 AND ITS VARIANTS (CYP2C9*2 AND CYP2C9*3) IN LORNOXICAM 5′-HYDROXYLATION

Drug Metabolism and Disposition, 2004
The effects of allelic variants of CYP2C9 (CYP2C9*2 and CYP2C9*3) on lornoxicam 5'-hydroxylation were studied using the corresponding variant protein expressed in baculovirus-infected insect cells and human liver microsomes of known genotypes of CYP2C9.
Izumi, Iida, Atsunori, Miyata, Masayuki, Arai, Mitsuyo, Hirota, Masayuki, Akimoto, Shohei, Higuchi, Kaoru, Kobayashi, Kan, Chiba   +7 more
openaire   +2 more sources

An identification and functional evaluation of a novel CYP2C9 variant CYP2C9*62

Chemico-Biological Interactions, 2020
Warfarin is the most commonly used anticoagulant in the clinical treatment of thromboembolic diseases. The dose of warfarin varies significantly within populations, and the dose is closely related to the genetic polymorphisms of the CYP2C9 and VKORC1 genes.
Hao, Chen, Da-Peng, Dai, Shan, Zhou, Jian, Liu, Shuang-Hu, Wang, Hua-Lan, Wu, Quan, Zhou, Pei-Wu, Geng, Jia, Chong, You, Lü, Jian-Ping, Cai, Jie-Fu, Yang   +11 more
openaire   +2 more sources